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Biomedical subjects

Y Moon

Publications and source records attributed to Y Moon.

23 records · Page 2Linked to original sources

Idiopathic parkinsonism with superimposed manganese exposure: utility of positron emission tomography.

It is difficult to distinguish manganism from idiopathic parkinsonism by clinical signs only. Case history and examination: A 48-year-old welder for over 10 years complained of masked face, right side (arm and leg) resting tremor, and bradykinesia for over one year. Magnetic resonance imaging (MRI) findings showed symmetrical high signal intensities in the globus pallidus on T1 weighted image. These intensities disappeared almost completely six months after cessation of exposure. 18F-6-fluorodopa (18F-dopa) positron emission tomography (PET) findings showed reduced 18F-dopa uptake in the left putamen, findings which appear in idiopathic parkinsonism. A PET study is necessary to distinguish manganism from idiopathic parkinsonism, especially in a working environment with elevated Mn concentrations, such as welding.

Diagnosis, Differential↗

Prostaglandin E and F concentration in the fimbria of the rabbit fallopian tube increases at the time of ovulation.

To see if the fimbrial concentrations of Prostaglandin E (PGE) and Prostaglandin F (PGF) change in the process of ovulation, these prostaglandins were measured in the fimbriae of one group of 18 doe rabbits using the specific radioimmunoassay; 13 rabbits were bred so as to induce ovulation and 5 rabbits were not bred. The PGE and PGF in the fimbriae of the 13 bred rabbits were 105.4 +/- 18.5 pg/mg of protein and 186 +/- 26.9 pg/mg protein, respectively. In the 5 control unbred animals, the fimbrial PGE and PGF concentrations were 39.6 +/- 5.9 pg/mg protein and 111 +/- 14.7 pg/mg protein, respectively (p less than 0.05). In an additional group of 8 rabbits (2 before ovulation and 6 after ovulation), it was found that the rise in the PGE and PGF concentration association with ovulation was maximal in fimbriae harvested immediately before ovulation (8 hours-8 hours 30 postcoitally) (p less than 0.001). These findings are consistent with the hypothesis that fimbrial PGE and PGF play a role in the process of ovum retrieval in the rabbit.

Animals↗