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Biomedical subjects

Y Miaux

Publications and source records attributed to Y Miaux.

46 records · Page 3Linked to original sources

Residual mediastinal mass in malignant lymphoma: value of magnetic resonance imaging and gallium scan.

Following treatment for mediastinal lymphoma, residual masses are defined as a mass greater than 2 cm observed on the CT scan in the absence of other evolutive signs of lymphoma. In this study, we examined 55 patients with residual mediastinal mass after optimal therapy, using gallium scan (37 cases) or magnetic resonance imaging (MRI, 44 cases). The group comprised 41 subjects with Hodgkin's disease and 14 with non Hodgkin's lymphoma, stages I and II (32 cases) and stages III and IV (23 cases); 35 subjects (64%) having bulky mediastinal involvement at diagnosis. A negative gallium scan or fibrotic signal on MRI was correlated with complete remission in 48 cases (87%). In seven of these 48 patients, MRI was not conclusive with a high signal of indeterminate tissue following radiotherapy, but four of the seven had fibrotic tissue on biopsy and none relapsed. Positive gallium scan was observed in six cases. In conclusion, we suggest performing a gallium scan at the end of induction chemotherapy and when it is negative, treatment may be continued without surgical biopsy or salvage therapy. MRI is of value when it shows fibrotic tissue but can be inconclusive.

Adolescent↗

MR imaging of breast hemangioma in female infants.

Breast hemangioma in female infants is a rare benign lesion, prone to spontaneous regression. But when the lesion regresses there is a risk of breast atrophy if the breast bud is included in or very close to the hemangioma. A trial of corticosteroid therapy could be proposed to prevent this risk, but one must be sure that the breast bud is included in or very close to the hemangioma before treatment. We studied 4 children with breast hemangioma to evaluate the ability of MR Imaging in the diagnosis of breast bud inclusion. 0.5 Tesla axial Spin Echo T2-weighted images (TR = 2000 ms; TE = 120 ms) clearly depicted interface between high signal appearance of hemangioma and hypo-intensity of the breast bud: in our four patients we were able to determine whether or not the hemangioma involved the breast bud. Our preliminary study seems to demonstrate that MR imaging is a valuable imaging technique to determine which patients could be eligible for a trial of corticosteroid therapy.

Breast Neoplasms↗

[Value of magnetic resonance imaging in the detection of intramedullary metastases of bronchial epidermoid carcinoma].

A 68 year old female presented with an intramedullary metastasis which was found to be caused by an epidermoid bronchial carcinoma. This type of metastasis is a rare complication and a diagnosis is difficult. The authors stress the importance of nuclear magnetic resonance as a non-aggressive diagnostic method which is very sensitive in detecting this type of pathology.

Aged↗

Imaging of choroid plexus infection by Stomatococcus mucilaginosus in neutropenic patients.

We report two neutropenic patients with Stomatococcus mucilaginosus meningitis and choroid plexus involvement on neuroimaging studies. CT and MR showed abnormal enlargement of the choroid plexus in one lateral ventricle and intense enhancement. In one patient there was edema in the periventricular white matter adjacent to the involved choroid plexus; in both patients there was enhancement of the ependyma.

Adolescent↗

Paraspinal arteriovenous fistula with perimedullary venous drainage.

A paravertebral presacral posttraumatic arteriovenous fistula drained through the ascending lumbar vein to the epidural plexuses and perimedullary veins. The patient did not have symptoms of myelopathy, only low-back pain and radicular hypoesthesia. The lesion was embolized with a large balloon and clinical symptoms disappeared.

Adolescent↗