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Biomedical subjects

Y Matsukado

Publications and source records attributed to Y Matsukado.

At least 163 records · Page 9Linked to original sources

[Diagnosis of the chiasmal meningioma (author's transl)].

Not infrequently, it is difficult to differentiate the chiasmal meningioma from other suprasellar tumors, especially pituitary adenoma and craniopharyngioma. Authors examined 7 cases of chiasmal meningioma from neurological, endocrinological and neuroradiological points of view in comparison with the cases of pituitary adenoma and craniopharyngioma. As the results, the following features can be regarded as the differential characteristics of the chiasmal meningioma. 1) It was predominated in female of over 40 years of age. 2) Duration of the symptoms before admission was usually 2--3 years. 3) Disturbance of visual acuity and defect of visual field were initially unilateral in most of the cases, then extended to the other side when the disturbance of one eye had become severe. Visual field defect tended to be of irregular bitemporal hemianopsia with frequent involvement of peripheral nasal field. 4) Evidence of the endocrine disturbance were very scanty until the end stage. 5) Postero-superior elevation of A1 portion of the anterior cerebral artery in the tuberculum sellae meningioma was one of the pathognomonic features. 6) In the case of meningioma extending from tuberculum sellae to dorsum sellae or originated from dorsum sellae, PEG showed a finding of "capping on the dorsum sellae" and the tumor shadow over the posterior clinoid process took different feature from pituitary adenoma or craniopharyngioma.

Adenoma↗

Structures and development of the venous system in congenital malformations of the brain.

Cerebral venograms of 21 clinical cases of midline anomalies of the brain and of 80 human fetuses between 3 and 8 months old were examined. The diagnostic value of the venogram was fully proven, particularly for the midline cerebral anomalies, where deep cerebral structures and configuration of the tentorium cerebelli were not well visualized by other neuroradiologic maneuvers. Abnormal structures of the deep cerebral veins as well as the dural sinuses in these malformations were proved to retain the venous structures in the early fetal period. The time of formation of these malformations was also inferred from the viewpoint of the venous development. Study of the fetal venous system was found quite useful for embryologic analysis and classification of congenital malformations of the brain.

Brain↗

Intracranial extracerebral brain heterotopia. Case report.

The authors describe a case of intracranial heterotopic brain located on the medial one-third of the left sphenoid ridge, and enveloped in a huge cystic cavity. The heterotopic brain was resected successfully with satisfactory clinical results. The resected brain was 8 X 4 X 3 cm in diameter, of 7 or 8 months gestational age, and consisted of cerebrum, brain stem, and cerebellum. Anatomical and cytoarchitectural findings of the heterotopic brain are presented.

Brain↗

[Actinomycotic brain abscess -case report- (author's transl)].

Actinomycosis of the central nervous system is rare. There has been considerable discussion as to whether it can be primary, but several cases have been reported occasionally. Authors presented a case of cerebral actinomycosis involving primarily the right frontal lobe through an obsolete stick wound. Patient is a 18-year-old man and when he was 8 years of age, he received right frontal penetrating injury due to fall on wire about 3 mm in diameter. Wound had healed sustaining any abnormal effect to note. Eleven years later, he was admitted to our institution because seizure attack characterized by automatism, and plain skull X-ray showed intracranial frontal calcification. EEG, angiography, RI scan and CT scan were performed. At operation, a granuloma was found and total removal was performed. The histological examination showed actinomycotic brain absess. Patient was treated with antibiotics and he returned to the previous occupation. Primary actinomycosis of the central nervous system was discussed with previously reported cases in the literature.

Actinomycosis↗

[Familial multiple hemangioblastomas--report of two cases in a family (author's transl)].

The authors reported their experience with two cases in a kindred with multiple hemangioblastomas in the cerebellum, brain stem, and spinal cord associated with von Hippel's disease, von Recklinghausen's disease and some visceral changes. (The members of this kindred died of similar disease.) Two patients, a 42-year-old man and his 14-year-old niece, showed various neurological signs involving central nervous system. Furthermore the man had some café-au-lait spots in the skin, a papillomatous tumors in the tongue and a vascular tumor in the right kidney. Both also had von Hippel's disease. Neuroradiological study and operations demonstrated multiple hemangioblastomas in the cerebellum, medulla oblongata and the spinal cord in association with abnormal enlargements of the medulla and the spinal cord which suggested coexistence of the parenchymatous tumor, probably glioma, in them. All hemangioblastomas in the cerebellum of both patients were removed. The literature of the familial multiple hemangioblastomas was reviewed and the coexistence of Lindau's disease, von Recklinghausen's disease and glioma was discussed.

Adolescent↗

Classification of cervical spondylosis or disc protrusion by preoperative evoked spinal electrogram. Follow-up study.

The evoked spinal electrogram (SEG) was studied in 11 patients with cervical spondylotic myelopathy or disc protrusion. All the patients were severely handicapped before surgery. The evoked SEG was classified in three grades before and during surgery. Periodic follow-up studies were done at 18 to 35 months, with an average of 24 months. Four of six patients were normal or slightly abnormal SEG recordings showed satisfactory improvement of the disability; however, only one patient showed any improvement when the recording was moderately or severely abnormal. Location of the cord lesion and type of surgery were similar in all patients examined, and the difference was likely ascribed to the physiological change of the intramedullary structures. The evoked SEG provides some information relative to the surgical treatment of spondylotic myelopathy or disc protrusion with cord lesion.

Aged↗

[Clinicophysiological studies of orbicularis oculi reflex in brain stem diseases].

Orbicularis oculi reflex is consisted of two components; one is early reflex response (R1) which is 14.1 +/- 2.2 msec in latency, and the other is late reflex response (R2) that is 35.0 +/- 8.6 msec in latency (mean +/- 2SD). R1 is observed on the ipsilateral side of stimulation and R2 is visible bilaterally on ipsiand contralateral sides of stimulation. Clinically orbicularis oculi reflex can be recorded easily, however, its clinical and physiological significance has not been clearly solved. Orbicularis oculi reflex was tested on patients with the brain stem lesions of various kinds, and the factors influencing to the reflex pathways were examined, such as the site and the type of lesions, sleep, several anesthetics and the level of consciousness. Results obtained were as follows; 1) both R1 and R2 disappeared or prolonged in latencies by nuclear as well as peripheral facial nerve palsy, since the facial nerve was the final common pathway. 2) on cases of facial sensory disturbance R1 prolonged in latency with concomitant delay of R2 response. 3) both R1 and were attenuated as soon as the alpha rhythmicity of the EEG was disappeared. Administration of thiamylal also attenuated both the R1 and R2, however, ketamine (a dissociative anesthetic) enhanced the R1 in amplitude and suppressed R2. These findings indicated that the R1 and R2 were in some extent regulated from brain stem reticular formation and the orbicularis oculi reflex should be an useful diagnostic measure to detect imparied consciousness. 4) also the reflex should be used to know the extent of neoplastic process in the cerebellar hemisphere to the brain stem. 5) recovery curve of R1 from double shock stimuli (conditioned and test) indicated that this reflex was different from H wave of the spinal cord because of absent refractory period and shorter facilitatory period ranging between 40 to 60 msec.

Adolescent↗