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Biomedical subjects

Y M Shi

Publications and source records attributed to Y M Shi.

32 records · Page 2Linked to original sources

[Alterations of the sympathetic activity, plasma catecholamine content and pulmonary surfactant in neurogenic pulmonary edema in rats].

Neurogenic pulmonary edema (NPE) was induced by microinjection of kainic acid into bilateral preoptic area (POA) of the hypothalamus in rats. Sympathetic discharge of the left adrenal branch was recorded, plasma catecholamine (CA) was assayed and the physical properties of pulmonary surfactant (PS) of the lung lavage were measured. The results showed that some physical properties of PS were changed in NPE, i.e. maximal surface tension (gamma Max) decreased, minimum surface tension (gamma Min) increased, recruitment index (RI), stability index and area of hysteresis loop (H-area) decreased. After injection of kainic acid into POA, the sympathetic discharge increased by 22.8 +/- 7.20% and 32.2 +/- 8.0% respectively at 30 and 60 min after injection and paralleled by a marked elevation of plasma catecholamine (CA). The results showed that PS activity had decreased at an early stage of NPE and the change of the plasma CA level was parallel to that of sympathetic discharge. It is suggested that generation of NPE may be related to some disorder of the autonomic nervous system at the level of hypothalamus, increase of sympathetic discharge, elevation of plasma CA level and fall of PS activity.

Animals↗

The therapeutic efficacy of the choleretic mixture against the infantile hepatitis syndrome.

Observation was made on a control study of the therapeutic efficacy of the choleretic mixture in treating 35 cases of infantile hepatitis syndrome in comparison with that of the choleretic decoction. The ages, duration of the disease, severity of icterus and serum bilirubin level in both groups were comparable. The results showed that there was no significant difference in therapeutic efficacy between the two groups, however, the resolving time of skin icterus was faster in the choleretic mixture group than in the choleretic decoction group. The choleretic mixture was convenient, easy to store, and acceptable to infants for its small dosage, and no side effects, therefore, a desirable drug against infantile hepatitis syndrome.

Drugs, Chinese Herbal↗

Experiences in the clinical use of the medial genicular flap.

Four cases with defects at varying sites were reconstructed with the medial genicular flap. Three cases utilized free microvascular skin flaps based on the saphenous artery and one case a pedicled flap based on the same artery. All flaps survived well with satisfactory functional and cosmetic results. Regional anatomy is briefly reviewed, dissection of the flap is described in detail, and some special technical points are mentioned.

Adult↗