HLA antibody formation was studied in 212 patients undergoing open-heart surgery on cardiopulmonary bypass in relation to the following variables: sex, obstetric history, transfusion history, quantity and nature of blood products transfused, type of oxygenator used, duration of bypass, and time of assay. Postoperative alloimmunization was seen in 33.6 percent of males and 64.3 percent of females. Previous pregnancy seemed to favor the development of antibody. No statistically significant correlation was noted between alloimmunization and the amount of blood products transfused. The best time for assay was day eight following surgery.

Adult↗

PubMedDate not supplied

[Williams-Beuren syndrome and renovascular arterial hypertension].

The Williams and Beuren's syndrome associates a particuliar facies, a mental debility, a supravalvular aortic stenosis, and frequent vascular anomalies of pulmonary artery as well as aorta and its branches. Relations between this syndrome and congenital idiopathic hypercalcemia seem now determined; the hypertension which has been frequently observed in this last case, seems more unusual in the case of Williams and Beuren's syndrome. The authors report a case about this syndrome in which the hypertension seemed linked to a stenosis of the left renal artery and which has been treated surgically. A year later the result is satisfactory but the evolutive potential of arterial lesions described in this syndrome does not necessory lead to a final recovery. Besides there are in this disease hypertensions which are relevant to an other etiology (more especially aortic hypoplasia) and stenosis of renal arteries without hypertension.

Adolescent↗

PubMedDate not supplied

[Bronchial tumor and paraneoplastic syndrome of antiduresis: a new case of Schwartz-Bartter's syndrome (author's transl)].

The autors reports about a new case of Schwartz-Bartter's syndrome. Its first clinical manifestations are primarily the neuro-psychiatric disorder and the arterial hypertension. These manifestations were attributed to an inappropriate secretion of antidiuretic hormon, in relation with a bronchial neoplasm (oat-cell carcinoma). The tumor was removed surgically; shortly after the operation the biological disorders disappeared completely. But they reappeared 5 months later, indicating recurrence (local and metastatic). This recurrence started to present clinical manifestation, 2 months later. After a brief historical approach, the authors suggested the aetiology, the diagnosis circumstances and the biological criteria of Schwartz-Bartter's syndrome. Then later, the precised the main principles of its management.

Bronchial Neoplasms↗