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Biomedical subjects

Y L Tong

Publications and source records attributed to Y L Tong.

5 recordsLinked to original sources

[Determination of tetramethylpyrazine and borneol in human plasma by GC-MSD].

A GC-MSD method for the determination of tetramethylpyrazine (TMP) and borneol in plasma is described. TMP and borneol were extracted with hexane-dichloromethane (10:1, V/V). Camphor was used as the internal standard. The average recoveries of TMP and borneol were 87.38% and 97.32% with relative standard deviation 1.90% to 6.21%, respectively. The method was successfully used to determine plasma borneol concentration following sublingual administration of 20 pills of Suxiao Jiuxin Wan to healthy volunteers (n = 10). The pharmacokinetic parameters have been listed in this paper.

Adult↗

Some distribution properties of the sample species-diversity indices and their applications.

In the area of ecological research the study of species diversity of a community or population seems to have been fully developed. However, the problem of how the distributions and expectations of the sample diversity indices are affected by the population diversity has received little attention. In this paper we show that if the diversities of the communities can be partially ordered through majorization as proposed by Solomon [1979, in Ecological Diversity in Theory and Practice, J. F. Grassle, G. P. Patil, W. K. Smith and C. Taillie (eds), 29-35, Fairland, Maryland: International Co-operative Publishing House], and if the sample sizes remain the same, then the sample diversity indices can be stochastically ordered when the samples are selected at random from the communities either with or without replacement. We also show that, when the sample size becomes large, the sample diversity indices are asymptotically normally distributed. These results can be applied for comparing the diversities of the communities on the basis of the samples, and they yield certain desirable monotonicity properties.

Animals↗

Some applications of inequalities for extreme order statistics to a genetic selection problem.

Two inequalities are derived for the extreme order statistics in a special case of unequally-correlated multivariate normal variables, and their implications in a genetic selection problem which was considered recently by Rawlings (1976, Biometrics 32, 875-887) and Hill (1976, Biometrics 32, 889-902; 1977, Biometrics 33, 703-712) are discussed. The inequalities establish a monotonicity property of the extreme order statistics as a function of the intraclass correlation, and they yield a chain of bounds when the family sizes are not all equal. Thus the inequalities extend the applicability of the results given by Rawlings and Hill to the more general case.

Animals↗

Parameter estimation in studying circadian rhythms.

In the model under consideration for the circadian rhythm study there are three unknown physiological parameters involved: the level, the amplitude and the phase. This paper concerns the estimation of the group level, group amplitude and group phase of a certain group of individuals based on their time series data. Special attention is paid to the amplitude and phase parameters, and solutions are obtained for both the small-sample and the large-sample cases.

Circadian Rhythm↗