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Biomedical subjects

Y L Chou

Publications and source records attributed to Y L Chou.

39 records · Page 3Linked to original sources

Physiological knock-knee in preschool children: prevalence, correlating factors, gait analysis, and clinical significance.

Physiological knock-knee (PKK) was categorized by measuring intermalleolar distance (IMD), a clinically simple method, to evaluate the prevalence and correlating factors in 305 preschool children. The prevalence in this cross-sectional study was relatively high, and it was age related (p = 0.002; 64, 44, and 34% for ages 3-4, 4-5, and 5-6 years, respectively). The following factors were correlated with PKK: use of walking chair early (p = 0.0001), independently walked late (p = 0.0005), dependently walked longer (p = 0.0001), concurrence with flatfoot (p = 0.001), and angular deformity (toe in/out, p = 0.03). Gait analysis, with spatiotemporal, kinematics, and kinetics parameters, was performed to evaluate the ambulatory significance. Preschool children with PKK have a shorter stride length (p = 0.02) and a slower walking speed (p = 0.004). Dynamic hyperextension of the knee is noted for 8 degrees during the whole gait cycle (p < 0.05). We conclude that PKK is a variable that should be considered in the development of mature gait for preschool children.

Child↗

Correlating factors and clinical significance of flexible flatfoot in preschool children.

To elucidate the correlating factors and clinical significance of flexible flatfoot (FF) in preschool children of Taiwan, a cross-sectional study was conducted in a research laboratory equipped with a gait analysis facility. Altogether, 377 preschool children (201 boys, 176 girls), ranging in age from 2 to 6 years, were enrolled in this investigation. The results show that age, height, weight, foot progression angle, occurrence of physical knock-knee, and joint laxity score correlate with FF. Children with FF, compared with children without, performed physical tasks poorly and walked slowly, as determined by gait parameters. The FF should not simply be regarded as a problem of static alignment of the ankle and foot complex, but may be the consequence of a dynamic functional change of the lower extremity. Better understanding of the correlating factors and the clinical relevance of FF may prove helpful in deciding on the most appropriate treatment for a particular patient.

Age Factors↗

Regeneration of plants from tobacco protoplasts and some factors affecting the plant differentiation.

Protoplasts were isolated from the cell suspension culture derived from leaf and stem calli of tobacco (Nicotiana tabacum cv. Ko Hsin No. 1) haploid pollen-plants. After 12 hr in the liquid culture medium, the protoplasts became oval-shaped, and produced a new cell wall. The first division of the newly formed cells was completed after 24 hr in culture. After 4 weeks in culture, the yellowish calli reached 1 mm in size were then transferred to an auxophyton. 18 days later, the calli became 3-4 mm in size. After the calli were transferred to a differentiation culture medium, shoots and roots soon turned up. Regeneration of whole plants was obtained thereafter. The division and differentiation of regenerated cells were affected not only by the calli originated from different organs and their, age, but also by the basic components of the differentiation culture medium and the type of cytokinin used.

Cell Differentiation↗