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Biomedical subjects

Y Korogi

Publications and source records attributed to Y Korogi.

At least 109 records · Page 6Linked to original sources

[Imaging of the pituitary gland].

Several modalities including plain radiography, CT, and MRI are available for evaluation of the intrasellar, suprasellar and parasellar lesions. Plain radiography, which may used for screening, can identify calcification as well as the elusive and destructive changes of the sella turcica and it's adjacent bony structures. CT is much more sensitive in detecting calcifications. It is also useful for demonstrating bony changes in detail. MRI has been thought to be the best modality in evaluation of sellar and parasellar lesions. Dynamic MRI is a choice of method when microadenoma is suspected.

Adolescent↗

Percutaneous transluminal angioplasty: pain during balloon inflation.

The pain during the balloon dilatation of angioplasty was evaluated prospectively to assess its clinical significance. In 54 angioplasties, no pain was observed in 54%, mild pain in 20%, moderate pain in 11% and severe pain in 15%. Moderate or severe pain was observed in 39% of 28 iliac angioplasties and in 7% of 14 femoral angioplasties. There was a significant difference between the two groups. We did not find any significant correlation between the severity of pain and stenotic ratio before angioplasty. Severe pain may be a warning of severe dissection; in our study, all severe dissections were accompanied by severe pain without arterial rupture.

Angioplasty, Balloon↗

Development of a ceiling-suspended angiographic unit for interventional neuroradiology.

A new neuroangiographic unit was developed with a ceiling-suspended gantry, capable of rotation (110 degrees) and craniocaudal angulation (+/- 45 degrees) along the body axis. The gantry could also be rotated 225 degrees at the ceiling suspension axis and sidetracked away from the angiographic table in case of emergency. Two sets of a twin-focus X-ray tube and a 12-inch image intensifier (II) were mounted on the gantry in the isocentric and cross-firing positions. High resolution 1024 x 1024 matrix digital radiography was obtained with a speed of 30 frames/s, while conventional film-screen radiography was obtained at 4 films/s. Rapid film changers were installed and interchangeable with the IIs. The lateral II and X-ray tube could be positioned from either side of the patient. There was no angulated position of the lateral imaging system during angulated anteroposterior or Towne projection of the frontal imaging system. Automatic repositioning of the gantry was possible to the preset position. Stereoscopic, magnification and stereoscopic magnification radiography could be obtained easily in monoplane or biplane mode. Switching from fluoroscopy to radiography and vice versa was possible rapidly and easily. Neuroangiographic as well as interventional procedures were performed expeditiously with lower complication rates. Suspending the gantry from the ceiling made more space available on the floor for the anesthesiologists.

Angiography↗

Normal and abnormal pituitary glands: gadopentetate dimeglumine-enhanced MR imaging.

Dynamic magnetic resonance (MR) imaging with a 1.5-T superconductive unit was used in the evaluation of nine normal pituitary glands and 10 pituitary adenomas, including four microadenomas and six macroadenomas. Seven to 10 images were obtained every 20-30 seconds with use of the spin-echo technique after rapid injection of gadopentetate dimeglumine. The earliest contrast material enhancement of normal structures was seen in the infundibulum and posterior lobe of the pituitary gland at 20 seconds, followed by gradual contrast material enhancement of the anterior lobe of the pituitary gland from the junction of the infundibulum to the peripheral portion of the anterior lobe of the pituitary gland within 80 seconds after gadopentetate dimeglumine injection. The peak enhancement of pituitary adenomas occurred at 60-200 seconds, usually after the most marked enhancement of the normal pituitary gland. Microadenomas are best visualized at earlier phases of gadopentetate dimeglumine-enhanced dynamic imaging, with signal intensity lower than that seen on images of normal pituitary glands.

Adenoma↗

Cavernous sinus: correlation between anatomic and dynamic gadolinium-enhanced MR imaging findings.

Dynamic magnetic resonance (MR) images were evaluated and compared with conventional T1-weighted spin-echo (SE) images obtained before and after administration of gadopentetate dimeglumine in 20 patients with normal cavernous sinuses. Starting 10 seconds after rapid injection of gadopentetate dimeglumine (0.1 mmol/kg), six to eight serial images were obtained every 30 seconds for 3-5 minutes. The venous spaces of the cavernous sinus were markedly enhanced 30 seconds after injection. Cranial nerves III and IV, V1 and VI, and V2 were seen on 75% of dynamic images each; they were seen, respectively, on 62%, 30%, and 28% of conventional postcontrast images. The medial wall was demarcated on 90% of dynamic, 15% of precontrast, and 55% of postcontrast images. A small area of connective tissue was identified within the cavernous sinus on dynamic images showing gradual enhancement. It is concluded that dynamic MR images proved useful in delineating and distinguishing abnormal tissue from normal structures.

Cavernous Sinus↗

[Percutaneous transluminal renal angioplasty: indication for renovascular hypertension associated with renal atrophy].

The results of clinical studies indicate that percutaneous transluminal renal angioplasty (PTRA) is an effective means for treating renovascular hypertension resulting from renal artery stenosis. However, the indications for the patients with renal failure or renal atrophy are not established on a firm ground. We attempted PTRAs of ten kidneys in nine patients with hypertension associated with renal atrophy. They were followed for an average of 8 months by the methods including blood pressure, angiography or DSA, blood chemistry, and RI-renogram. We also evaluated enlargement of the renal size on an angiogram or on a plain film at DSA. Angiographic follow-up showed persistent relief of the stenosis in all cases. After PTRA, blood pressure reduced to normal or improved in two thirds of the patients for the follow-up period. In the study of three patients with excellent results for blood pressure, two patients showed the renal length to be increased by 1.0 cm or more, and one patient by 0.5 cm. In the same group, RI-renogram also showed good response. These data indicate that PTRA could improve total perfusion on the affected kidneys. On the other hand, in three patients with no change in blood pressure, there was poor response in both the renal size and the data of RI-renograms. We suggest that the irreversible changes might have occurred in these kidneys. It was difficult to predict cure group from no change group before PTRA.

Adult↗

Primary carcinoid tumor of the liver: a case report.

A very rare case of primary carcinoid tumor of the liver that underwent hepatic artery embolization is reported. Computed tomography showed a low-density tumor with little contrast medium enhancement, whereas angiography revealed a slightly hypervascular mass in the liver. The computed tomography findings after hepatic artery embolization showed a marked decrease in attenuation and gas formation.

Carcinoid Tumor↗

Computed tomography demonstration of renal dysplasia with a vaginal ectopic ureter.

The diagnosis of renal dysplasia associated with a single vaginal ectopic ureter is often difficult, because the dysplastic kidney is usually not seen on excretory urography. A 17-year-old girl, whose affected kidney was accurately identified by computed tomography, is reported. Computed tomography is a useful technique for the diagnosis of renal dysplasia with a single vaginal ectopic ureter.

Adolescent↗

Percutaneous transluminal angioplasty of totally occluded iliac arteries in high-risk patients.

Percutaneous transluminal angioplasty was performed successfully in five of six patients with complete iliac artery occlusion. All of the patients were at high risk because of various co-existing diseases. The length of occlusion ranged from 3.0 cm to 12.0 cm. No significant complications requiring surgery occurred during or after the procedures. Follow-up of patients revealed that the vessels were still patent after 3-22 months. Percutaneous transluminal angioplasty of totally occluded iliac arteries may represent the therapy of first choice even in the high-risk group.

Aged↗

Evaluation of high resolution digital subtraction angiography in neuroradiology.

A digital subtraction angiography (DSA) system has been modified for capabilities of a 1024 x 1024 matrix with 10 bit depth. Spatial resolution was increased with expansion of the matrix, but contrast resolution was not increased as determined by phantom experiments. Smaller focal spots and magnification factors were also important for improvement of spatial resolution. Clinical evaluation using carotid, vertebral, and cervical DSA with intra-arterial contrast injections demonstrated that there was slight improvement in the image quality, but the final diagnosis and management of patients were not changed with the use of high resolution DSA. Further improvements in image quality of DSA will be accomplished by improvements of image intensifiers and use of smaller focal spots.

Angiography, Digital Subtraction↗