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Biomedical subjects

Y Koganei

Publications and source records attributed to Y Koganei.

4 recordsLinked to original sources
PubMed1989

Postoperative sequelae of augmentation mammaplasty by injection method in Japan.

Postoperative sequelae of 696 cases following augmentation mammaplasty by the injection method have been studied. The most frequently used foreign material for injection was silicone. Paraffin had been previously used somewhat less frequently. Of the 696 cases studied, the most common complications were hardening, skin change, transformation, and pain. Of the total number of cases studied for removal of the foreign material, 244 were seen in university hospitals and 416 in private clinics. Reaugmentation was performed in many cases using both a flap technique and bag prostheses with no significant degree of incidence of complications following reaugmentation.

Breast↗
PubMed1988

Orbital lipoma.

A patient who had a huge orbital lipoma with extension to the muscle cone is described. The lipoma was 42 x 34 x 32 mm in size, and there was no visual disturbance following removal of the tumor and iliac bone grafting. Diagnosis of orbital lipoma is difficult to make. This is particularly true of a lipoma with an obvious capsule, which cannot be easily differentiated from a dermoid cyst. However, computed tomography scanning is useful in ascertaining the location, size, and relationship with orbital contents. A review of the literature concerning orbital lipoma revealed only a few reports, and the features of the orbital lipoma are summarized. In addition, the possible mechanism of orbital enlargement and the approach to the muscle cone are described.

Adult↗
PubMed1988

Biological evaluation of burn blister fluid.

Human dermal fibroblasts were cultured with blister fluid and 3 of their properties were investigated: cell shape, growth rate, and ability to contract collagen fibrils. In the medium containing the blister fluid, fibroblasts became attached to the tissue culture plastic and became well elongated to a spindle form. The blister fluid demonstrated a potent fibroblast growth-promoting activity comparable to that observed in the serum obtained from the same patient. This activity was independent of the patient's age and the time elapsed since the burn. The growth rate of cells increased as the concentration rose to 20% in the case of serum. Growth promotion by the blister fluid, however, was maximum at the concentration of 2.5%, leveling off thereafter, a fact which suggests the presence of some other factor possessing an inhibitory action on fibroblast growth. The growth-promoting activity of the blister fluid was not destroyed by tryptic digestion. The blister fluid promoted a fibroblast-mediated contraction of collagen fibrils to an extent comparable to that of the serum. The protein-banding pattern of the fluid, obtained by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate, was similar to that of the serum. These results suggest that the fluid is an exudate mainly from the vascular system, that is provides a good environment for the fibroblasts in the damaged site, and that it facilitates the healing process.

Adolescent↗