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Biomedical subjects

Y Kihara

Publications and source records attributed to Y Kihara.

At least 163 records · Page 9Linked to original sources
PubMed1983

[New approach for quantifying left ventricular regional wall motion in ischemic heart disease: motion vector analysis of endocardial surface by two-dimensional echocardiography].

To quantify regional wall motion of the left ventricle with two-dimensional echocardiography, the motion of an endocardial surface point in echocardiograms was analyzed throughout systole on frame by frame using video motion analyzer. With a fixed external reference system and in the "69% point (C)" by Ingels et al, the motion vector (M) of a point was expressed in two components; the contracting component (Y) directed toward the point C, and the component vertical to it, the shearing component (X). In the control group, the magnitude of M and its contracting component were widely varied with the location along the endocardial surface (5.6 +/- 1.6, 5.0 +/- 1.5 mm in the apex, 10.9 +/- 2.2, 10.4 +/- 2.0 mm in the inferior base, p less than 0.001 and p less than 0.001, respectively). The shearing component and the angle theta at which M and Y meet, showed narrow normal ranges (1.9 +/- 1.4 mm, 15.1 +/- 1.4 mm, 15.1 +/- 11.2 degrees), and were independent of their locations. In the ischemic group, however, the points of non-ischemic regions showed low values of theta (14.9 +/- 8.9 degrees), which were not significantly different from those of the control group, while the points of ischemic regions showed high values of theta (over 2SD of the control group). The distribution of these points with abnormal theta values was well correlated to that of the segments with asynergic motion evaluated by both real-time two-dimensional echocardiography and left ventriculography (p less than 0.001 and p less than 0.001, respectively). These results suggest that this new approach with quantitative echocardiography is sensitive and specific for the assessment of regional wall motion of the left ventricle and may provide accurate clinical information for the evaluation of ischemic heart disease.

Adolescent↗
PubMed1983

[Radiotherapy for post-operative inflammatory breast cancer].

Two patients with inflammatory breast cancer treated with a combination of radical mastectomy, irradiation, and immunochemotherapy are reported. After radical mastectomy, both patients were given a dose of 4000 rad and 5000 rad to the chest wall and parasternal lymph nodes, and 5000 rad to the axillary and supraclavicular lymph nodes. However, both patients died of recurrence within the irradiated field of the chest wall and metastatic spread to the neighbouring skin. A discussion on the dose and field in radiation therapy for inflammatory breast cancer is presented.

Adenocarcinoma↗
PubMed1977

Arylsulfatase of human tissue. Studies on a form of arylsulfatase B found predominantly in brain.

The distribution of soluble arylsulfatase (aryl-sulfate sulfohydrolases, EC 3.1.6.1) in human tissues was investigated by DEAE-cellulose chromatography, All tissues examined contained arylsulfatase A and arylsulfatase B. In addition, brain singularly contained significant quantities (15-25% of total arylsulfatase) of a minor anionic arylsulfatase from designated arylsulfatase Bm, whereas only trace amounts of arylsulfatase Bm were found in liver, kidney, testis and placenta. Arylsulfatase B and arylsulfatase Bm had equal activity toward methyl-umbelliferyl sulfate, nitrocatechol sulfate and a physiological substrate UDP-N-acetylgalactosamine 4-sulfate, but both forms were inactive toward the arylsulfatase A substrates cerebroside sulfate and ascorbic acid 2-sulfate. Purified preparations of placental arylsulfatase B, brain arylsulfatase Bm, and urinary arylsulfatase A did not hydrolyze estrone sulfate, dehydroepiandrosterone sulfate or pregnenolone sulfate. The physico-chemical properties of arylsulfatase Band arylsulfatase Bm differed with respect to thermal lability, DEAE-cellulose chromatography, polyacrylamide gel electrophoresis and isoelectric focussing. In the latter technique, utilizing thin polyacrylamide slab gels, the isoelectric point for placental arylsulfatase B was 8.2, while brain arylsulfatase Bm resolved into 3 activity bands with pI values 6.8, 7.0 and 7.2. Although the physico-chemical properties differed, arylsulfatase B and arylsulfatase Bm appear to be functionally equivalent as well as generically related.

Brain↗
PubMedDate not supplied

Embolotherapy for persistent hemoptysis: the significance of pleural thickening.

Elective embolotherapy for recurrent hemoptysis was evaluated for its effectiveness. Forty embolotherapeutic procedures were performed in 30 patients. In the short term, complete hemostasis was achieved in 16 of 40 procedures (40%) and significant improvement in another 16 procedures (40%). Long-term, complete hemostasis was achieved in 14 of 34 procedures (41%) and significant improvement in 12 (35%). Embolotherapy was consistently more effective in patients who had no pleural abnormalities compared with those with pleural thickening. Long-term complete hemostasis was achieved in 7 of 10 procedures (70%) for the patients without pleural thickening and only 7 of 24 (29%) in patients with pleural thickening. Thus, pleural abnormalities negatively influence long-term effectiveness of embolotherapy.

Adult↗
PubMedDate not supplied

Magnetic resonance imaging of retained surgical sponges. Case report.

The magnetic resonance imaging (MRI) features of sponges retained postsurgically in three patients are described. MRI depicted these as well-defined round masses, which were of low signal intensity on T1-weighted images and very high signal intensity on T2-weighted images. We scrutinized these masses on T2-weighted images. MRI revealed the low-signal-intensity structures to have wavy, striped, and/or spotted appearances, which raised the suspicion that they might be retained surgical sponges within mass lesions.

Aged↗
PubMedDate not supplied

Retroperitoneal leiomyosarcoma. Its MR manifestations.

The magnetic resonance manifestations of retroperitoneal leiomyosarcomas in two patients are described. The tumors were isointense to muscle on T1-weighted images and exhibited a relatively high signal on T2-weighted images. Postcontrast T1-weighted images after the administration of gadolinium-dietilenetriaminepentaacetic acid produced moderate enhancement except in regions of central necrosis.

Humans↗
PubMedDate not supplied

Pseudo lesions on CTAP secondary to arterio-portal shunts.

PURPOSE: To clarify the characteristics of the defects on computed tomography (CT) during arterial portography (CTAP) due to arterio-portal shunting (APS). METHOD AND PATIENTS: The defects in the hepatic parenchyma on CTAP due to angiography proven APS were characterized according to their configuration, size, sharpness of margins, location of the lesion in the liver, and homogeneity of the lesions. RESULTS: Twenty five patients had non-tumor related APS. The shunts were single on angiography in 15 cases and multiple in 10 cases. The APS were due to liver cirrhosis in 22 patients, and to trauma in the other three. The lesions were irregular in shape in nine cases, wedge shaped in six cases, and round in four cases. In three cases both wedge and round lesions were seen. The margins were sharp in five single defects in five cases. The rest of the lesions were judged to have unsharp margins except for one case in which both clear and unclear lesions were present. In 10 cases, internal enhancement of the lesions were seen on CTAP. The location of the defects were central in five cases, peripheral in nine, and both peripheral and central in eight cases. CONCLUSION: The parenchymal defects due to APS were typically irregular in shape, with unsharp margins and internal enhancement.

Adult↗