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Biomedical subjects

Y Kenan Coban

Publications and source records attributed to Y Kenan Coban.

At least 19 recordsLinked to original sources

Eccrine porocarcinoma arising from preexisting eccrine poroma of the scalp after radiotherapy for cervical cancer.

Eccrine porocarcinoma may arise from eccrine poroma or it may occur de novo. We present a rapidly growing occipital malignant eccrine poroma on the scalp following to a radiotherapy for cervical carcinoma. A wide excision with skin grafting resulted no recurrence during a 1-year followup. Although malignant transformation is well known for other skin cancers this was not reported for eccrine poroma.

Acrospiroma↗

Pyogenic granuloma on the hand subsequent to friction blister in a hand surgeon.

A case of pyogenic granuloma in a 62-year-old hand surgeon secondary to friction blister is reported. He developed a fast growing, hypertrophic inflammatory papule consisting of exceptionally richly vascularized granular tissue. This dusky red lesion was located on the thenar part of the hand. We find no prior report of PG attributed to friction blister.

Friction↗

Serum IL-18 is increased at early postburn period in moderately burned patients.

A severe systemic inflammatory response is usually seen after burn injury. IL-18 enhances the Th1 immune responses in bacterial andviral infections. In order to evaluate the IL-18 serum levels as well as IL-6 and TNF-alpha at the 48th hour postburn, serial serum samples of 8 burned patients were analyzed. 8 moderately burned patients were included into the study. Serum samples were taken at admission at the 48th hour of postburn. IL-6, IL-18, and TNF-alpha serum levels were analyzed. Total mean burned surface area (TBSA) was 24.6 +/- 5.7% and mean BMI (body mass index) was 24.5 +/- 3.4. The patients' age ranged from 17 to 38 (mean 26.3 +/- 7.4) years. An increase in sera IL-6, IL-18, and TNF-alpha was detected at the 48th hour postburn (P < .0001). All patients survived. A marked increase in serum levels of IL-18 as well as the other cytokines evaluated was observed in the moderately burned patients. These three parameters were highly correlated with each other (r > 0.9 and P < .001). This is the first study that shows an increase in serum IL-18 levels at the early postburn period.

Adolescent↗

Ovarian cortical transplantation may be an alternative to hormone therapy in patients with early climacterium.

OBJECTIVE: To discuss the 18-month follow-up results of fresh ovarian cortical tissue transplant. DESIGN: Case study. SETTING: Academic medical center. PATIENT(S): A 46-year-old patient who was operated on for uterine fibroids, and who then received an ovarian tissue transplant in July 2003. INTERVENTION(S): Serum hormone levels were measured at 3-month intervals. MAIN OUTCOME MEASURE(S): Follicular development evident by ultrasound examination; serum hormone levels (FSH, LH, E2). RESULT(S): Preoperative and 3rd-, 6th-, 9th-, 12th-, 15th-, and 18th-month hormone levels were, respectively, as follows: FSH: 9.06, 79.5, 13.7, 16.66, 51.91, 44.37, and 24.17 mIU/mL; LH: 5.91, 33.92, 8.78, 21.83, 38.31, 40.85, and 22.4 mIU/mL; E2: 166, 46, 48, 117, 31, 14.4, and 137.7 pg/mL. Folliculogenesis was confirmed by ultrasonography at the 6th, 9th, and 18th months during the follow-up period. CONCLUSION(S): Fresh ovarian autotransplantation may be a logical alternative for hormonal support for a specific patient group.

Climacteric↗

A transverse rectus abdominis myocutaneous (TRAM) flap for reconstruction of a large deformity in the buttock: a new indication for a TRAM flap.

A rectus abdominis myocutaneous flap has been used to repair the abdominal wall, chest wall, sternum, breast, and groin. We describe a patient in whom a large deformity in the buttock caused by a road crash was repaired with a transverse rectus abdominis myocutaneous (TRAM) flap. Distally-based TRAM flaps provide a good and reliable way of reconstructing the buttock. Its advantages are a long arc of rotation and well-vascularised bulky tissue that serve as a partition and promote quick healing of the defect. However, the flap is not the first choice for traumatic and infected wounds where fatty tissue is not desired.

Adult↗

Low-volume tumescent liposuction does not change plasma malondialdehyde levels: a preliminary study.

To evaluate the effects of low-volume tumescent liposuction on plasma malondialdehyde (MDA) levels, a controlled clinical study was conducted. Venous blood samples were taken just before and 10 min after the completion of tumescent suction-lipectomy for 15 patients. The means +/- standard deviations for patients' data were as follows: of patients' age (29.81 +/- 13.2 years) aspirate volume (1,250 +/- 450 ml), and body mass index (24.5 +/- 1.2). There was no significant difference between the preoperative and postoperative plasma malondialdehyde levels (p > 0.05). The results show no evidence of increased lipoperoxidation in the systemic circulation during low-volume tumescent liposuction.

Adult↗

Correction of buttock ptosis with anchoring deepithelialized skin flaps.

A new technique for correction of a buttock ptosis resulting from a degloving injury is presented. With this technique, the deepithelialized crescent-like zone in lateral thigh redundancy anchored to gluteal fascia through three separate incisions as used for creation of a new gluteal crease. The patient's satisfaction was good with long-term follow-up evaluation. Infragluteal fold reconstruction is achieved by reconstruction of the buttock's sustaining apparel through deepithelialized skin flaps anchored to deep gluteal fascia.

Adipose Tissue↗

Fresh autologous transplantation of ovarian cortical strips to the anterior abdominal wall at the pfannenstiel incision site.

OBJECTIVE: To describe an open surgical technique for transplanting fresh ovarion tissue to the anterior abdominal wall at the incision site and to determine whether ovarian function would be restored after transplantation. DESIGN: Case study. SETTING: Academic medical center. PATIENT(S): A 44-year-old patient who underwent an operation for uterine fibroids. INTERVENTION(S): Microsurgical reconstruction of ovarian cortex and its transplantation to the anterior abdominal wall at incision site of Pfannenstiel. MAIN OUTCOME MEASURE(S): Follicular development evident by ultrasound examination; restoration of serum FSH and LH levels to nonmenopausal range; and disappearance of menopausal symptoms. RESULT(S): Early postoperative FSH, LH, and E(2) levels showed that menopause was confirmed. Postoperative hormone levels at months 2, 3, and 6 were as follows: FSH: 77.86, 79.50, and 13.70 mIU/mL; LH: 34.60, 33.92, and 8.78 mIU/mL; E(2): 29, 46, and 48 pg/mL. The patient is still followed-up for postmenopausal status. CONCLUSION(S): Autotransplantation of cortical strips to the anterior abdominal wall at the incision site without further incision can be a logical solution for the patients at early climacteric age.

Abdominal Muscles↗

Three new cases of disorganizationlike syndrome: one with accessory extrophia vesicalis.

The authors report 3 unrelated Turkish cases of disorganizationlike syndrome. All of these patients have accessory limbs, and 2 of them have accessory genitourinary structures. Interestingly, one of these patients has extrophia vesicalis of accessory bladder. None of them have chromosomal abnormality. Here the authors present distribution of findings of these cases.

Abnormalities, Multiple↗