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Biomedical subjects

Y Kawase

Publications and source records attributed to Y Kawase.

152 records · Page 9Linked to original sources

Peritoneal washings cytology combined with immunocytochemical staining in pancreatic cancer.

BACKGROUND/AIMS: Peritoneal washings from patients with pancreatic cancer demonstrate malignant cells in 0-58% of patients. But the significance of their potential for implantation and growth after radical surgery has not been clarified. METHODOLOGY: Peritoneal washings were collected from 74 consecutive pancreatic cancer patients during a 5-year period and studied by conventional staining and immunocytochemical staining using anti-CEA and anti-CA 19-9. Fifty of the 74 patients were resectable and the others were nonresectable. RESULTS: Seven out of 8 patients with macroscopic peritoneal metastasis were positive in conventional staining, but all 8 patients were positive in immunocytochemical staining. Five of the 66 (8%) patients without macroscopic peritoneal metastasis were positive in conventional staining, but the positive rate increased to 14 of 66 (22%) in immunocytochemical staining. There was no statistically significant difference in post-operative cumulative survival rate between the 13 positive cytology patients and 37 negative cytology patients without macroscopic peritoneal metastasis. CONCLUSIONS: The positive rate of peritoneal washings cytology was increased in this study by the use of immunocytochemical staining in addition to conventional staining. No statistically significant difference in post-operative cumulative survival rate between positive cytology patients and negative cytology patients without macroscopic peritoneal metastasis was observed.

Adenocarcinoma↗

Perfusion, inhalation, and ventilation studies in patients with primary lung carcinoma.

To determine the relative roles of perfusion, inhalation, and ventilation lung scintigraphy, studies were done respectively in 48, 50, and 34 of 54 primary lung carcinoma patients (prior to thoracotomy and subsequent radical tumor resection). We observed the relationships between both the size of perfusion, inhalation, and ventilation defects observed scintigraphically, and the size of the mass lesion seen radiologically. We also estimated the correlation between those scintigraphic classifications and pTN. Although inhalation and perfusion images exhibited similar patterns, in hilar type lung carcinoma patients, the inhalation study showed superior mass lesion delineation. In peripheral type lung carcinoma, however, the incidence of negative inhalation defect (52%) differed significantly from that of negative perfusion defect (21%) (p less than 0.05). Xe-133 gas ventilation has limitations but is occasionally helpful in detecting obstructive airway disease. The coexistence ratio of COPD in lung carcinoma patients showed no significant difference from that of COPD in the controls. Perfusion and inhalation classification did not correlate with pTN factor.

Adenocarcinoma↗

Bronchial and vascular supply in azygos lobe of inflated fixed lung: a case study.

Azygos lobe is a comparatively rare anomaly of the lung, and its radiologic features are well known. However, reports concerning its bronchial and vascular supply are few. The authors describe the bronchial and vascular supply of an azygos lobe in the autopsied right lung of a 43-year-old man. In the inflated fixed lung, the azygos lobe was supplied by the bronchi of the apical sub-subsegmental branch of B1b (B1bi) and B1a (B1ai) accompanied by the accompanied by the pulmonary artery of the same sub-subsegments (A1bi, A1ai). The lateral sub-subsegmental branches of B1aii and B1bii accompanied by the pulmonary artery did not supply the azygos lobe. The azygos lobe was supplied by V1a. V2 but not V1b.

Adult↗

CT-pathologic correlation in the tumor margins of lung cancer.

A CT-pathologic correlative study concerning the nature of the tumor margin was performed in 22 lung cancer cases with solitary nodules in the peripheral lung field. Three of 14 adenocarcinoma cases showed an ill-defined margin and an adjacent subtle high attenuation area on CT, representing alveoli lined by tumor cells. In the other 11 cases, both ill- and well-defined margins were seen on CT. A well-defined margin of the mass represented alveoli filled entirely with mucinous material or tumor cells. In three of six squamous cell carcinomas an ill-defined margin in CT represented the infiltration of lymphatic cells surrounding the tumor and continuous spread of tumor cells from neighboring alveoli. A well-defined margin in the other cases and two small cell carcinoma cases represented alveoli filled entirely with tumor cells. CT was shown to be very useful in the assessment of the nature of the margin of the tumor.

Adenocarcinoma↗

Rounded atelectasis formation following decrease of pleural effusion: a case report.

We present a case of rounded atelectasis (RA) observed continuously following decrease of pleural effusion. The collapsed right lower lobe adjacent to pleural effusion changed its shape from wedge-shaped consolidation with air-bronchogram to oval and flat formation at last. The vessels and bronchi curving into RA were detected by CT and we called it horizontal comettail sign. When a mass is detected following decrease of pleural effusion and vessels and bronchi are curving into the mass, the mass may be diagnosed as RA and no further examination may be necessary.

Bronchography↗