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Biomedical subjects

Y Kawada

Publications and source records attributed to Y Kawada.

At least 271 records · Page 15Linked to original sources
PubMed1978

Microbial degradation of cephalothin by cephalothin-susceptible Escherichia coli.

Cephalothin (CET)-susceptible Escherichia coli, which can degrade CET after prolonged incubation in broth containing a concentration of the drug greater than the minimum inhibitory concentration, was found in a clinical specimen. The substrate specificity of the partially purified enzyme to cephalosporin analogs strongly indicated the occurrence of CET-specific degradation. Nuclear magnetic resonance analysis of the degradation reaction demonstrated the appearance of two new signals attributed to deacetyl CET. This suggests the possibility of the presence of acylesterase.

Cephalothin↗
PubMed1977

Angiography before and after radiotherapy for a thalamic tumor.

A patient with a thalamic tumor received radiotherapy. A right cerebral angiogram seven days after the irradiation was finished revealed increased vascularity, early filled deep cerebral veins and signs of increased mass. A subsequent angiogram showed gradual regression of these features. There is no literature on angiographic progression with early venous filling following radiotherapy.

Adult↗
PubMed1977

[Acute epidural hematoma with extravasation on cerebral angiogram in an infant (author's transl)].

The authors recently operated on a boy four years of age with acute epidural hematoma showing an extravasation on the cerebral angiogram. The hematoma (hematoma volume 125 ml) was evacuated 7 hours after the head injury. The postoperative course was quite uneventful, and he was discharged a month after surgery without any neurologic deficits. The authors reviewed the literature and found 4 cases of acute epidural hematoma with extravasations in infants and children. In all cases the operative results were good. The age incidence and frequency of occurence overall for acute epidural hematomas, extravasations on cerebral angiograms and their mechanism, and the length of time from injury to operation were also discussed. It should be emphasized that, for acute epidural hematoma in infants and children, the early diagnosis and early surgery are essential to save the patients.

Acute Disease↗
PubMed1976

[Application of parenteral cephradine in urinary tract infections (author's transl)].

A new antibiotic cephradine was administered intravenously for 3 approximately 7 days at daily doses of 1.0 approximately 2.0 g to 56 patients, including 39 cases of acute urinary tract infections, 13 of chronic urinary tract infections and 4 for postoperative prophylaxis. Of 39 cases with acute urinary infections, definite response was seen in 35 cases and no definite response in 4 cases. Of 13 cases with chronic urinary tract infections, definite response was seen in 7 cases and no definite response in 6 cases. Good results were obtained clinically in 4 cases for prophylaxis of postoperative infections. No side effect was observed with cephradine with cephradine throughout the experiment.

Acute Disease↗