Search PubMed⌕ Search

Biomedical subjects

Y Kanter

Publications and source records attributed to Y Kanter.

At least 37 records · Page 2Linked to original sources
PubMed1983

Electrocardiographic patterns in diabetics without clinical ischemic heart disease.

Resting ECG patterns were studied in 42 young diabetic patients and in 40 matched control subjects. There was no clinical ischemic heart disease in either group. Discriminant analysis showed significant differences between the two groups: diabetics typically had a higher heart rate, a leftward frontal QRS axis, a prolonged corrected QT interval and ST segment and T wave changes. Using resting ECG variables we were able to correctly classify 62 (75%) of the 82 patients studied. The findings support the existence of a nonischemic diabetic cardiopathy.

Adult↗
PubMed1982

Computerized medical decisions in evaluating the diabetes patient.

A system for computer simulation of medical reasoning is described which has been applied to classifying diabetic patients and assessing the complications due to disease. Medical knowledge is formulated into modular, interrelated inference pathways. Each module states the inference and the Boolean combinations of criteria sufficient for confirming or rejecting it. Patient data is compared to the medical logic and a status report is produced which presents the clinical findings, confirmed inferences, the diabetes evaluation score for each body system and request for additional data at the follow-up visit. After initial testing the medical logic was easily updated to fully express medical policy in our clinic. The system provides an objective and consistent method for evaluating the diabetic patient.

Diabetes Complications↗
PubMed1982

Adult Still's disease associated with pregnancy.

A 23-yr-old woman in her sixth month of pregnancy presented with the systemic variant of juvenile rheumatoid arthritis (Still's disease). The symptoms included high fever, erythematous evanescent maculopapular rash, hepatosplenomegaly and asymmetric arthritis. During a follow-up period of 1 yr, anti-inflammatory drugs (both steroidal and nonsteroidal) were administered, leading to the eventual disappearance of the patient's complaints. Adult-onset Still's disease reported in the literature is reviewed, and the association of Still's disease with pregnancy is discussed.

Adult↗
PubMed1980

Complete remission of Cushing's disease by total bilateral adrenalectomy and adrenal autotransplantation.

A 15-yr-old girl was diagnosed as suffering from Cushing's disease. She was treated by bilateral adrenalectomy and autotransplantation of one third of each adrenal to the corresponding thigh. The adrenal that was embedded in the right satorius muscle started functioning after about 1 yr, as proven by significant differences in cortisol levels in both femoral veins (82.5 and 17.5 micrograms/100 ml). 19-[131I]Cholesterol scanning showed adrenal tissue in the right thigh, while no adrenal remnant was demonstrated. Eleven years after surgery, the patient is symptom free and does not require replacement therapy. We find that adrenal autotransplantation, which is a simple and nonrisky procedure, should be considered whenever bilateral adrenalectomy is chosen as a treatment for Cushing's disease.

17-Ketosteroids↗
PubMed1980

Improved glucose tolerance and insulin response in obese and diabetic patients on a fiber-enriched diet.

Twenty-two subjects, six of them obese, five latent diabetics, six overt diabetics, and five control subjects, were given a daily dietary supplement of 16 g guar gum and 10 g pectin for three successive days. Postprandial blood glucose and insulin responses to an initial standard meal and to a fiber-enriched meal given 72 h later were compared. A significant decrease of blood glucose levels was found in all subjects, with maximal response in the obese group. We conclude that supplementing the diet with certain fibers can be regarded as an important therapeutic measure in the treatment of diabetic and obese patients.

Adolescent↗
PubMed1977

2,3-diphosphoglycerate, nucleotide phosophate, and organic and inorganic phosphate levels during the early phases of diabetic ketoacidosis.

The relation between serum and red blood cell (RBC) inorganic phosphate levels, RBC 2,3-diphosphoglycerate (2,3-DPG) levels, RBC nucleotide phosphate (Pn), and RBC total phosphate (Pt) levels were studied during the early phases of treatment and recovery from diabetic ketoacidosis (DKA). A steady drop in serum inorganic phosphate was found during the first 24 hours of insulin treatment and was most profound at 24 hours. No statistically significant changes (P less than 0.05) were found in red cell inorganic phosphate or nucleotide phosphate levels during the 24-hour study period. The levels of total red cell phosphate were lower in this group of patients than in nonacidotic diabetic subjects and decreased slightly after 24 hours of treatment. The red cell 2,3-DPG levels were low at the initiation of therapy and remained low during the 24-hour study period. Glucose, bicarbonate, lactate, and ketone levels fell in linear patterns with treatment. In view of the current evidence for the effects of low 2,3-DPG on oxygen delivery and the relation of low serum phosphate levels to RBC glycolysis and 2,3-DPG formation, this study reemphasizes the need for phosphate replacement during the early phases of treatment of DKA.

Adenosine Triphosphate↗
PubMed1975

Red cell 2, 3-diphosphoglycerate levels among diabetic patents with and without vascular complications.

There have been differences of opinion among authors concening in the levels of red cell 2,3-diphosphoglycerate (2,3-DPG) and nucleotides in nonacidotic diabetic patients. Our data suggest that abnormal levels of 2, 3-DPG in diabetic patients are related to the presence of vascular complications and not to the duration of the disease per sec. 2,3-DPG levels are normal in diabetic patients with no evidence of vascular complications (group A). In ambulatory patients with vascular complications (group B), significantly higher levels of 2,3-DPG are found than in normal subjects and patients in group A. In hospitalized diabetic patients with active peripheral vascular complications (group C), levels of 2,3-DPG are likewise significantly increased over those of normal subjects and patients of group A. 2,3-DPG was found to be significantly elevated in patients of group C as compared with group B. 2,3-DPG levels in venous blood from infected legs as compared with those of the peripheral venous blood were not significantly different, thereby ruling out local factors. There were no differences in the blood lactate levels in any of the group studied. The elevation of the 2,3-DPG levels may be a reflection of attempted red blood cell compensation for tissue hypoxia in the diabetic with vascular disease.

Cerebrovascular Disorders↗