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Biomedical subjects

Y Ishihara

Publications and source records attributed to Y Ishihara.

At least 343 records · Page 19Linked to original sources

Effect of ACTH on the relaxation of guinea pig trachea with various bronchodilators.

The effect of ACTH on the actions of various bronchodilators was examined using the isolated guinea pig tracheal smooth muscle. Relaxing effects of isolated guinea pig tracheal smooth muscle with 1-isoproterenol hydrochloride, salbutamol hemisulfate, hexoprenaline hydrochloride and epinephrine except prostaglandin E2 and aminophylline were markedly potentiated by combining ACTH. These results may suggest that ACTH has a direct effect on guinea pig tracheal smooth muscle by potentiating the actions of various beta-receptor stimulators.

Adrenocorticotropic Hormone↗

Radioimmunoassay of main urinary metabolite of prostaglandin F2alpha in normal subjects.

Radioimmunoassay of 5alpha, 7alpha-dihydroxy-11-keto-tetranor-prosta-1,16-dioic acid, main urinary metabolite of prostaglandin F2alpha (PGF2alpha-MUM), was performed in normal subjects. Twenty-four hours secretion of PGF2alpha-MUM were 29.04 +/- 9.73 microgram in males and 18.22 +/- 5.88 microgram in females on an average. And an oral administration of aspirin resulted in the remarkable decrease of PGF2alpha-MUM in both sexes.

Aspirin↗