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Biomedical subjects

Y Ingenbleek

Publications and source records attributed to Y Ingenbleek.

41 records · Page 3Linked to original sources
PubMedDate not supplied

[Prealbumin and the nutritional status of the newborn infant].

Thyroxine-binding prealbumin (TBPA) appears as a sensitive blood parameter for assessing various forms of protein and calorie malnutrition, ranging for subclinical protein deficit to frank kwashiorkor. More precisely, TBPA serves as a valid marker for determining both protein nutritional adequacy and the optimal ratio of energy and zinc to nitrogen intake in healthy newborns and preterm infants without infection. When inflammation is present, the decrease in TBPA blood levels reflects a deterioration in the patient's condition and its increase monitors the efficacy of dietary management. In this latter inflammatory context, it is recommended to combine the measurement of TBPA with that of the most reliable indicators of the phlogistic reaction, allowing the discrimination of both infectious and nutritional poles of the disease spectrum.

Humans↗
PubMedDate not supplied

Soybean oil, blackcurrant seed oil, medium-chain triglycerides, and plasma phospholipid fatty acids of stressed patients.

Thirty-six adult severe head injury and cerebral stroke patients in four intensive-care units were randomized to receive one of three enteral diets for 21 days. These diets, which supplied 45% of calories from fat, differed only in lipid composition. Diet A was comprised of 100% soybean oil, diet B contained a 50:50 (wt/wt) mixture of soybean oil and medium-chain triglycerides (MCTs), and diet C contained 42.5% MCT, 50% soybean oil, and 7.5% blackcurrant seed oils. Plasma phosphatidylcholine and fatty acid composition of plasma total phospholipids were determined before initiating treatment (day 0) and weekly throughout the study. Results indicated that at the start of the study, all patients had low linoleic acid (18:2 omega 6) levels compared with healthy subjects. Emulsion A disturbed the balance between several fatty acids of the omega 6 series, as exemplified by the significant increase in 18:2 omega 6 proportions. In contrast, both emulsions B and C introduced a less-pronounced rise in 18:2 omega 6 associated for emulsion C with a significant increase in dihomo-gamma-linolenic acid (20:3 omega 6) and docosapentaenoic acid (22:5 omega 3) in plasma phospholipids. Furthermore, 18:3 omega 6 change was significantly different between groups A and C and that of 20:3 omega 6 between group A and both groups B and C. Throughout the study, arachidonic acid (20:4 omega 6) exhibited remarkable steady-state levels regardless of the diet. This study shows that providing the injured body with high amounts of 18:2 omega 6 does not lead to high levels of its upper derivatives in plasma phospholipids.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗