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Biomedical subjects

Y H Chong

Publications and source records attributed to Y H Chong.

At least 37 records · Page 2Linked to original sources

Effect of loading and syringing on void formation in automixed addition silicone elastomers.

The effect of loading and syringing on void formation in five automixed addition silicones was evaluated by determining the voids created in the first and second halves of material loaded and dispensed from a metal syringe. Impressions were made of a model with six stainless-steel cylinders. The voids were counted at a predetermined site on 3 separate days using a binocular microscope at x 7 magnification. Automixed addition silicones did not confirm the 'last out-fewer bubbles' phenomenon and specific loading and syringing technique did not appear to have a consistent effect on void formation in automixed elastomers.

Dental Impression Materials↗

Single discolored tooth: an alternative treatment approach.

A single discolored tooth is often difficult to treat, but one with an obliterated pulp chamber and root canal presents an even greater challenge. The use of nightguard bleaching is offered as a simpler, alternative treatment to either root canal therapy or the removal of sound tooth structure for fabrication of a facial veneer or a complete-coverage crown.

Adult↗

Radiation dosage of a dental imaging system.

This study compared the radiation dosage necessary for obtaining clinically acceptable images with a new dental imaging system (radiovisiography) to that required with a conventional-film radiographic technique. Results showed that radiovisiography required significantly less radiation exposure, only 22.3% of that used in the conventional technique. Problems, such as lack of flexibility and the limited size of the x-ray-sensitive surface, are associated with radiovisiography; however, the system effectively complements conventional-film radiography.

Humans↗

Dental prosthetic status and needs of an elderly population living in long-term care facilities in Singapore.

This study examined the prosthetic status and needs among an elderly population living in long-term care facilities in Singapore. A total of 488 subjects were randomly selected and 479 of them were examined. The results show that 56.2 percent of selected subjects were edentulous while 43.8 percent had one or more teeth missing. The average number of teeth present among dentate subjects was 7.5. Of the edentulous subjects, 78 percent of them reported not having any dentures, and more than 20 percent of existing dentures were found to be defective and had to be replaced. A higher proportion (94 percent) of dentate subjects who could have benefitted from having partial dentures did not have them. The findings of this study clearly demonstrate high unmet needs for prosthetic care among an institutionalized elderly population.

Aged↗

Dental state and needs for episodic care of institutionalized elderly in an Asian community.

This study examined the dental state of institutionalized elderly and their need for care. An oral examination was carried out on 479 elderly persons living in long-term care facilities with a mean age of 74.9 years. Results showed an overall DMF score of 27.0 and the average number of teeth in dentate subjects was 7.5. A large proportion of teeth (76.6%) was lost through dental caries and the loss increased significantly with age. Consequently, 56.1% of subjects were edentulous, of whom 78.8% were without dentures. Among the conditions that required urgent dental care, majority of subjects needed extractions of residual roots and loose teeth. A lesser proportion required treatment for gross caries (4.8%), periodontal disease (5.0%), suspected tumor (0.2%), as well as alleviation of pain and infection arising from mucosal lesions (4.8%), abscesses (3.3%) and TMJ problems (2.8%). The treatment needs for dentures and episodic care are high among institutionalized elderly and need to be addressed.

Aged↗

Effect of operator variability on void formation in impressions made with an automixed addition silicone.

This study examined voids produced in impressions of an automixed addition-reaction silicone. Two operators took the impressions using material dispensed from either intra-oral tips or an impression syringe. The material was also hand-mixed for comparison. There were no differences in the number of voids in the automixed material dispensed using the intra-oral tip or impression syringe. Automixing produced substantially fewer voids than hand-mixing. There was a significant difference in the number of voids in the impressions made by the two operators.

Dental Impression Materials↗

Relationship of viscosity to porosities in automixed elastomeric impressions.

Porosities commonly presenting as voids have been recognized as an inherent problem in elastomeric impressions. Automixing of the impression has been found to be effective in reducing voids. The purpose of this study was to compare formation of voids in medium-viscosity and putty-wash materials in four automixed addition silicone elastomers. Impressions of a master model were made according to manufacturers' recommendations on manipulation of materials. Voids presenting on a predetermined surface were counted under a binocular microscope at a magnification factor of 7x. Results showed that Express exhibited a significantly higher number of voids than other materials in both categories. Putty-wash impressions generated significantly less voids than medium-viscosity impressions for all materials except Reprosil. The findings of this study suggested that putty-wash impressions produced significantly less porosities than medium-viscosity impressions and, consequently, offer better tear strength for impressions.

Dental Impression Materials↗

Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee).

A double-blind, crossover, 8-wk study was conducted to compare effects of the tocotrienol-enriched fraction of palm oil (200 mg palmvitee capsules/day) with those of 300 mg corn oil/d on serum lipids of hypercholesterolemic human subjects (serum cholesterol 6.21-8.02 mmol/L). Concentrations of serum total cholesterol (-15%), LDL cholesterol (-8%), Apo B (-10%), thromboxane (-25%), platelet factor 4 (-16%), and glucose (-12%) decreased significantly only in the 15 subjects given palmvitee during the initial 4 wk. The crossover confirmed these actions of palmvitee. There was a carry over effect of palmvitee. Serum cholesterol concentrations of seven hypercholesterolemic subjects (greater than 7.84 mmol/L) decreased 31% during a 4-wk period in which they were given 200 mg gamma-tocotrienol/d. This indicates that gamma-tocotrienol may be the most potent cholesterol inhibitor in palmvitee capsules. The results of this pilot study are very encouraging.

Adult↗

Dietary tocotrienols reduce concentrations of plasma cholesterol, apolipoprotein B, thromboxane B2, and platelet factor 4 in pigs with inherited hyperlipidemias.

Normolipemic and genetically hypercholesterolemic pigs of defined lipoprotein genotype were fed a standard diet supplemented with 50 micrograms/g tocotrienol-rich fraction (TRF) isolated from palm oil. Hypercholesterolemic pigs fed the TRF supplement showed a 44% decrease in total serum cholesterol, a 60% decrease in low-density-lipoprotein (LDL)-cholesterol, and significant decreases in levels of apolipoprotein B (26%), thromboxane-B2 (41%), and platelet factor 4 (PF4; 29%). The declines in thromboxane B2 and PF4 suggest that TRF has a marked protective effect on the endothelium and platelet aggregation. The effect of the lipid-lowering diet persisted only in the hypercholesterolemic swine after 8 wk feeding of the control diet. These results support observations from previous studies on lowering plasma cholesterol in animals by tocotrienols, which are naturally occurring compounds in grain and palm oils and may have some effect on lowering plasma cholesterol in humans.

Animals↗

Defects in automixed addition silicone elastomers prepared by putty-wash impression technique.

Voids presenting in impressions of five automixed addition silicone elastomers were investigated. Impressions were prepared with the putty-light body impression technique on stainless-steel cylinders with acrylic spacers. The number of voids was counted at a predetermined site on three separate days using a stereomicroscope at x7 magnification. Impression specimens of a hand-mixed addition silicone, and from hand-mixing of the automixed materials, were made for comparison. Express gave a significantly higher number of voids than other automixed materials, with President Jet having the lowest void count. Automixed materials generally produced impressions with significantly fewer voids than the hand-mixed material. Automixing was effective in reducing void defects in elastomeric impressions.

Dental Impression Materials↗

Characterization of the antigenic domains of the major core protein (p26) of equine infectious anemia virus.

A panel of recombinant trpLE-gag fusion proteins and synthetic peptides was used in Western immunoblot and enzyme-linked immunosorbent assays to identify segments of the major core protein (p26) of equine infectious anemia virus that are antigenic in horses during experimental and natural infections with the virus. The predominant humoral immune response was directed toward a highly immunogenic domain composed of 83 amino acids from the carboxy terminus of p26. The observed immunogenicity of p26 resembled that reported for p24 of human immunodeficiency virus type 1, suggesting the conservation of structural motifs in the lentiviral core proteins which are responsible for their observed immunogenicity during persistent lentivirus infections.

Animals↗

Analysis of equine humoral immune responses to the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus.

Defined segments of the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus were expressed as TrpLE fusion proteins and examined for their reactivity in Western immunoblots against a diverse panel of equine immune sera. The most immunogenic region of gp45 was localized to its amino terminus, positioned between the hydrophobic fusion and the transmembrane domains. A series of overlapping synthetic peptides were used in enzyme-linked immunosorbent assays to define an immunodominant epitope within this region. In contrast, the carboxy-terminal half of gp45 displayed both weak and variable immunoreactivity with equine immune sera.

Amino Acid Sequence↗

Effectiveness of intraoral delivery tips in reducing voids in elastomeric impressions.

Voids in impressions made by five automixed addition silicone elastomers with and without intraoral delivery tips were investigated. The number of voids were counted at a predetermined site on 3 days. Hand-mixed impressions of the automixed materials were made for comparison. There was no statistically significant difference in the mean number of voids produced in each automixed silicone dispensed with the use of intraoral delivery tips and the number of voids produced without the use of the tips. However, there were significant differences in the number of voids among different materials. The rank order of the automixed silicone elastomers was fairly consistent, with Express producing the highest and Reprosil the lowest number of voids. Automixed silicone materials should only be prepared by automixing for optimal results.

Air↗

Effects of palm oil on cardiovascular risk.

A major public health concern of affluent nations is the excessive consumption of dietary fats which are now closely linked to coronary heart disease. Against this scenario, the tropical oils and palm oil in particular, have been cast as major villains in the U.S.A., despite the fact that palm oil consumption there is negligible. The unsuspecting public may not realise that the call to avoid palm oil is nothing more than a trade ploy since in recent years palm oil has been very competitive and has gained a major share of the world's edible oils and fats market. Many also lose sight of the fact that, palm oil, like other edible oils and fats, is an important component of the diet. The allegation that palm oil consumption leads to raised blood cholesterol levels and is therefore atherogenic is without scientific foundation. Examination of the chemical and fatty acid composition of palm oil or its liquid fraction should convince most nutritionists that the oil has little cholesterol-raising potential. The rationale for these are: it is considered cholesterol free. its major saturated fatty acid, palmitic acid (16:0) has recently been shown to be neutral in its cholesterolaemic effect, particularly in situations where the LDL receptors have not been down-regulated by dietary means or through a genetic effect. palm oil contains negligible amounts (less than 1.5%) of the hypercholesterolemic saturated fatty acids, namely lauric acid (12:0) and myristic acid (14:0). it has moderately rich amounts of the hypocholesterolaemic, monounsaturated oleic acid (18:1, omega-9) and adequate amounts of linoleic acid. (18:2, omega-6). It contains minor components such as the vitamin E tocotrienols which are not only powerful antioxidants but are also natural inhibitors of cholesterol synthesis. Feeding experiments in various animal species and humans also do not support the allegation that palm oil is atherogenic. On the contrary, palm oil consumption reduces blood cholesterol in comparison with the traditional sources of saturated fats such as coconut oil, dairy and animal fats. In addition, palm oil consumption may raise HDL levels and reduce platelet aggregability. As with all nutrients, there is a need to obtain a balance of different fatty acids found in fats in edible oils and other food sources. There is no single ideal source of fat that answers to the recent American Heart Association's call to reflect a 1:1:1 ratio of saturated, monounsaturated and polyunsaturated fats in relation to the recommended dietary fat intake of 30% of calories or less.(ABSTRACT TRUNCATED AT 400 WORDS)

Animals↗

Effect of interchanging automatic mixing tips on void formation for an automixed addition silicone impression.

This study examined the effect of interchanging mixing tips on void formation for impressions of an automixed addition silicone material. The impressions were made of a series of stainless-steel cylinders by two dentists. The voids were counted at a predetermined site with a binocular microscope. The results showed that there were no significant variations in the number of voids in impressions of the automixed addition silicone using the three different mixing tips. However, one dentist made impressions that had substantially less voids for all three mixing tips.

Air↗

Relationship between contact angles of die stone on elastomeric impression materials and voids in stone casts.

Poor wettability of elastomeric impression materials results in surface defects on stone casts. This study examined the relationship between contact angles of die stone and voids in casts produced from five medium-viscosity impression materials. Contact angles of a die stone material formed against impression specimens made from polyether, addition and condensation silicones were measured by reflex microscope. The contact angle values achieved on the hydrophilic addition silicones were significantly higher than the polyether but lower than other silicone materials. Contact angle values correlated with the number of voids found at margins and line angles of stone casts but not with those on smooth surfaces.

Dental Impression Materials↗