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Biomedical subjects

Y F Tu

Publications and source records attributed to Y F Tu.

4 recordsLinked to original sources
PubMed2001

Studies of a disposable biosensor based on the beta-cyclodextrin inclusion complex as mediator.

This paper reports the use of a disposable voltammetric biosensor based on a screen-printed basal electrode and highly efficient mediators, the beta-cyclodextrin inclusion complexes tetramethylbenzidine and ferrocene. The polyphenol oxidase, contained in the crude extract of mushroom, was immobilized in the membrane of the cross-linked beta-cyclodextrin polymer. The resulting biosensor gave excellent analytical performance due to the supramolecular complexation for mediators. It responded to the concentration of dopamine with high selectively in the range from 1.0 x 10(-9) to 1.0 x 10(-6) M with a detection limit as low as 5 x 10(-10) M. The response time for reaching 90% of its steady-state value was less than 60 s, and the activity was retained for at least 15 days.

Agaricales↗
PubMed1995

Hypothalamic hamartoma and gelastic epilepsy: a case report.

We studied a 6-year-old girl who presented with inappropriate and uncontrollable laughing episodes since age 3. Physical examination revealed a precocious puberty. The luteinizing hormone-releasing hormone (LH-RH) stimulation test showed an increased level of follicle-stimulating hormone (FSH). The interictal electroencephalogram (EEG) was normal. Several laughing fits were documented during video/EEG monitoring. During laughing, the ictal EEG showed a diffuse suppression of background rhythm, prominent over the left mesial temporal region. A mass lesion about 2 x 2 cm in size was found over the suprasellar cistern with a broad base attached to the hypothalamus, which was isodense on a computed tomography (CT) scan, isointense to gray matter on T1-weighted magnetic resonance (MR) imaging and hyperintense on T2-weighted MR imaging. The findings were suggestive of a hypothalamic hamartoma. A variety of anticonvulsants had been used with little or no response to the frequency or duration of the laughing seizures.

Child↗
PubMed1995

Startle epilepsy presenting as drop attacks: a case report.

A case of startle epilepsy, induced by an unexpected touch on the left shoulder of a 3.5 year old boy, was investigated. The startle epilepsy manifested as an atonic drop attack. Neurological examination revealed a mild hemiparesis on the left side. Computed tomography (CT) scanning demonstrated an enhancement over the right parieto-frontal region, suggesting a hemangioma. Interictal electroencephalography (EEG) showed diffuse slowing and asymmetry of background activities with lower amplitude over the right centro-parieto-temporal region. The ictal EEG showed a paroxysmal bilaterally synchronized high amplitude single spike followed by a few slow waves lasting about one second over the bilateral centro-parieto-temporal regions. The seizure resisted anticonvulsant therapy and no significant responses were observed despite the use of combined therapy with valproic acid, phenytoin, primidone and clonazepam.

Child, Preschool↗