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Biomedical subjects

Y Cordoliani

Publications and source records attributed to Y Cordoliani.

11 recordsLinked to original sources
PubMed2001

Familial form of cerebral cavernous malformations: evaluation of gradient-spin-echo (GRASE) imaging in lesion detection and characterization at 1.5 T.

The purpose of this study was to evaluate the turbo gradient-spin-echo sequence (GRASE) in the MR assessment of the familial form of cerebral cavernous malformations (CCM). Twenty-one patients (15 male, six female) aged from 21 to 68 years (mean = 42.2 years) were prospectively examined with cerebral MR imaging, including T2-weighted turbo gradient-spin-echo (TGSE), turbo spin-echo (TSE) and gradient-echo (GRE) sequences. All sequences were performed in the same plane, the same matrix and the same field of view and were analyzed for signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), susceptibility effects, number of CCM, size of CCM and signal of CCM. It was found that SNR and CNR in the TGSE sequence were significantly inferior to those in both TSE and GRE sequences. TGSE and TSE sequences were significantly less prone to susceptibility effects than the GRE sequence. The sensitivity of TGSE and TSE sequences in detecting CCM was significantly lower than that of the GRE sequence. TGSE and TSE sequences provided comparable information about CCM size and signal. It was concluded that GRASE imaging was less sensitive than the GRE sequence in the detection of CCM and provided information similar to that yielded by the TSE sequence in the characterization of lesions, but with a higher number of artifacts. GRASE imaging cannot therefore replace TSE or GRE sequences in the MR evaluation of the familial form of CCM.

Adult↗
PubMed2000

[Metastasis in pulmonary arteries].

We report two cases of pulmonary tumor emboli. The first patient had a chondroblastic osteosarcoma of the pelvis while the second patient had a seminoma. The possibility of tumor emboli should be entertained in patients with prior history of malignancy presenting with enlargement of the pulmonary arteries and thrombus enhancement on delayed scans.

Adult↗
PubMed2000

[Cerebellopontine angle tumors in adults].

Cerebellopontine angle tumors in adults are mainly benign and extra-axial. Magnetic resonance imaging is the first method for their diagnosis, CT being more useful for bony structures evaluation. Vestibular schwannoma is the most common lesion, it presents as a rounded mass centered along the axis of the internal acoustic meatus, the largest portion being in the cerebellopontine angle. The tumor enhances after Gadolinium administration. Meningioma is the second most common tumor; this slow growing mass has a wide attachment to the adjacent dural mater and is dramatically enhanced by contrast. Epidermoid cyst the third mass, is an extra-axial lesion with the signal is similar to the one of cerebrospinal fluid. Other lesions such as lipoma, papilloma, glioma or metastasis account for less than 1% of the cerebellopontine angle cistern tumors in adults.

Adult↗
PubMed2000

[Brain functional MRI: physiological, technical, and methodological bases, and clinical applications].

Brain functional MRI (fMRI) provides an indirect mapping of cerebral activity, based on the detection of the local blood flow and oxygenation changes following neuronal activity (BOLD contrast, Blood Oxygenation Level Dependent). fMRI allows us to study non invasively the normal and pathological aspects of cortical functional organization. Each fMRI study compares two different states of activity. Echo-Planar Imaging (EPI) is the technic of choice that makes it possible to study the whole brain at a rapid pace. Activation maps are calculated from a statistical analysis of the local signal changes. Functional MRI is now becoming an essential tool in the neurofunctional work-up of many neurosurgery patients, as well as the reference method to image normal or pathologic functional brain organization in adults and children.

Adult↗
PubMed1992

[Staging evaluation and surveillance in tumors of the testicle].

In 1992, the staging and follow-up of testicular germ cell tumours is based on a combination of computed tomography and tumour markers. Due to the development of medical imaging over the last decade, abdominal and thoracic CT has now replaced the combination of lymphography and pulmonary tomographies. Testicular ultrasonography is valuable for the diagnosis and contributes to staging and follow-up. The chest x-ray is still performed and MRI has very exceptional indications. Tumour markers, essentially alpha-foetoprotein and the free beta fraction of human chorionic gonadotrophin, are useful in more than 80% of NSGCTs and about 15% of seminomas (beta-HCG alone). A very high initial level often indicates a poor prognosis. Monitoring of markers is essential after exclusive orchidectomy and to assess the efficacy of chemotherapy.

Aftercare↗
PubMed1989

[Rhinopharyngeal craniopharyngioma. CT X-ray and MRI aspects].

The authors report about a rare site of craniopharyngioma, purely extracerebral and located in the sphenoid sinus and the rhinopharynx. No CT or MRI sign is pathognomonic for the lesion, but the presence of a fleshy process containing calcifications and cystic formations must lead to evoking this diagnosis. MRI assesses the extent of the lesions perfectly, but fails to detect small calcifications or ossifications accurately.

Adult↗