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Biomedical subjects

Y Chaouat

Publications and source records attributed to Y Chaouat.

At least 37 records · Page 2Linked to original sources
PubMed1979

[Value of metrizamide myelography with tomodensitometry for study of the cervical spine].

52 metrizamide myelographies practiced with tomodensitometry were studies (23 normal cases); 6 cervicarthrosic myelopathies; 2 intra medullar tumors; 1 extra medullar tumor; 19 syringomyelias). The technical procedures are discussed for the different diseases. This test has proven highly interesting for the study of syringomyelias and tumors. It allows the presence of narrow canals to be demonstrated, but does not yet indicate discal hernias. The role of tomodensitometry, in relation to other exams, is demonstrated.

Humans↗
PubMed1979

[Cervical arthrosic myelopathies. Study of a series of 35 cases. Pathogenetic and therapeutic reflections].

A series of 35 myelopathies was studied. The clinical characteristics are detailed. Gaseous myelography remains the best contrast test for establishing this diagnosis, making it possible to distinguish between spinal cords with constriction by stages and "trestle spinal cords" these two conditions often seem related. The medical treatments are disappointing, and one can improve the lesional syndrome but rarely the post-lesional syndrome. Surgery by posterior laminectomy gives in the long run only 45 per cent of improvement. On the basis of these observations, the authors state the opinion that the majority of the cases combining a cervicarthrosis and melyopathy after the age of 55, reveal of mixed, vascular and mechanical pathogeny. Surgery appears most useful in young patients whose spinal cord is congenitally constricted and shows sings of clinical distress.

Adult↗
PubMed1978

[Study of 108 cases of cervico-brachial neuralgia: the concepts of idiopathic cervico-brachial neuralgia and cervico-arthrotic cervico-brachial neuralgia].

On the basis of a series of 108 cases of cervicobrachial neuralgia a study was made of the clinical characteristics, circumstances of appearance, associated neurological signs, sequelae, relapses, and aetiologies of these observations. This series permits consideration of the aetiopathogenesis of cervicobrachial neuralgias of rheumatic origin from a new angle. The disco-osteophytic nodule does not appear to play the role classically attributed to it. Three forms are distinguished: idiopathic cervicobrachial neuralgia of transient occurrence with a cyclic duration and little tendency to recurrence and not related to concomitant arthrotic lesions; long-term cervicobrachial neuralgia lasting more than 20 weeks and always requiring a search for narrow canal and root anomaly -sometimes the form of onset of cervicarthrotic myelopathies; cervico brachialgia caused by cervicarthrosis seen after the age of 60 and consisting of projected pain rather than true cervicobrachial neuralgia, often recurrent.

Adult↗
PubMed1978

[Cases of acute leukaemia following immunosuppressive therapy for disseminated sclerosis and for Behçet's syndrome (author's transl)].

On the basis of two personal cases of acute leukaemia occurring following immunosuppressive therapy for disseminated sclerosis and for Behçet's syndrome, the literature is reviewed. Thirty three similar detailed cases were collected. They are characterised in general by the prolonged use of immunosuppression. The acute leukaemia affected the granulocyte series in the majority of cases. In 30%; the leukaemia was preceded by a phase of several months of preleukaemic type dysmyelopoiesis. The mechanisms of action explaining this carcinogenic risk in a general way are multiple: the role of marrow aplasia, chromosomal abnormalities, the activation of a leukaemogenic virus, the role of immunodepression and that of repeated antigenic stimulation may all be discussed. The risks associated with such treatment should thus be borne in mind when evaluating its indications.

Behcet Syndrome↗
PubMed1977

[HLA markers and periodic disease [familial Mediterranean fever (F.M.F.)] (author's transl)].

Thirty-one unrelated patients, 15-52 years old, were typed by microlymphocytotoxicity for 27 alleles of the HLA system. In addition, 12 families including 1 or more patient were also analysed. This criteria for diagnosis were those of Sohar et all. (Am. Intern. Med., 1967, 43, 227-253). All patients were of Israelite-Sephardin origin except two (Armenian and French); they were from North-Africa (Tunisia, Morocco and Algeria) and Israël. The results were compared to the antigen frequencies of 3 reference normal populations. The frequencies of the studied alleles do not differ from those of controls, except for HL-A28 and B14 slightly increased when compared to the normal frequencies. The study of 7 families with at least two sibs suffering from FMF shows a random distribution of the genotypes : 2 HLA identical, 6 different and 10 haploidentical diseased sibs. This distribution differs significantly (p less than 0.01) from that expected in the case of a recessive inheritance. These data do not support the hypothesis of a linkage between genes controlling FMF and HLA genes.

Adolescent↗
PubMed1976

[Osteoid osteoma. 5 cases].

With reference to five cases of osteoid osteoma, including two para-articular cases with articular reaction, two cases with neurological manifestations, and one case with a rare costal lesion, the authors demonstrate the difficulty of diagnosis in this disease, which is, in principle, well known. In some cases the observations extended over seven years. The authors also review the literature on this subject.

Adolescent↗
PubMed1975

[Neurosensory complications of Paget's disease].

The authors made a bibliographic study and report their conclusions with reference to problems concerning a personal series of 17 patients who had undergone an ocular examination, a cranial radiography studying the joint, a bilateral radiotomographic study of the ossicles and of the petrosal bone, an audiogram, and a bilateral electronystagmogram: 1. the rarity of angioid striae, the existence of which, in the view of the authors, does not allow Paget's disease to be included within the framework of the systemized elastorrhexis, 2. the frequency of ocular vascular lesions, 3. deafness is a constant phenomenon, when the cranial arch is affected usually in combination with other lesions ; the deafness is sometimes of transmission or sometimes of perception, but it can precede the cranial lesions. The signs of these can be found radiologically in the chain of ossicles and in the cochlea by means of special projections. The part played by basilar pressure in this deafness is negligible. Labyrinth disorders are rarely met.

Angioid Streaks↗
PubMed1974

[Rheumatic manifestations of primary hypogammaglobulinemia in the adult].

With reference to 27 cases reported in the literature (of which 1 was personal) of primary hypogammaglobulinaemia in adults (PHGGA) with rheumatic manifestations, and following a statistical study, the authors think that the rheumatic manifestations that precede, accompany, or follow primary hypogammaglobulinaemia in adults are not coincidental. These manifestations occur in 10 percent of patients. The clinical and radiological pictures, and the associated infections and immunological disorders form a particular clinical entity and lead to therapeutic difficultires. In this connexion, the authors mention in particular pathogenic problems related to hypogammaglobulinaemia in adults and the rheumatic manifestations.

Adolescent↗