[Cervical lymphatic metastasis with a high number of affected ganglia in carcinomas of upper aerodigestive tract].
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Biomedical subjects
Publications and source records attributed to Y Cachin.
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Rendu-Osler disease is an hereditary disease due to a predominantly antosomic heredity. The statistics given for 50 cases include 27 males 7 p. 100 of which had no familial antecedents. Clinically, Rendu-Osler disease begins in adulthood (44 p. 100) and often in late adulthood. In fact, it does not become really severe until about the age of 50 or 60. Epistaxis is the most frequent accident and proves fatal in more than 10 p. 100 of cases. Treatment of the nasal symptoms, whether this involves surgical excision followed by grafting or plesiocurietherapy using irridium wires, is very disappointing. The future alone will prove whether embolization gives more permanent results.
Malignant neoplasia of head and neck in children are mostly embryonal sarcoma and non Hodkgin's lymphomata. Squamous-sell carcinomas are only 10%. The main locations are in nasopharynx and paranasal sinuses. Symptoms are corelated with location of the primary. Treatment depends of the pathologic type. Combination of chemotherapy and radiotherapy, and sometimes surgery, yield now more cured patients, especially in embryonal sarcoma.