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Biomedical subjects

Y Bacq

Publications and source records attributed to Y Bacq.

78 records · Page 5Linked to original sources
PubMedDate not supplied

[Relation between plasma catecholamines, the severity of the liver disease and hemodynamics in patients with cirrhosis].

Plasma noradrenaline and adrenaline concentrations were measured in 75 patients with cirrhosis in order to attempt to correlate these concentrations and liver failure and hemodynamic changes. The increased noradrenaline concentration was not correlated with the degree of liver failure estimated by Pugh's classification, with the cause of cirrhosis, with the presence of acute alcoholic hepatitis or with the presence of ascites. Adrenaline concentration was higher in cirrhotic patients with acute alcoholic hepatitis than in those without these lesions. Noradrenaline concentration was significantly correlated with heart rate, wedged hepatic venous pressure and renal blood flow. Noradrenaline concentration was also negatively correlated with stroke volume and adrenaline concentration was negatively correlated with cardiac output and stroke volume. These findings confirm the relationships between portal hypertension, sympathetic hyperactivity and renal function in patients with cirrhosis.

Adult↗
PubMedDate not supplied

[Schistosoma mekongi bilharziasis along the Mekong River and its affluents, the Mun and Tonle Sap Rivers. General review].

First cases of Schistosomiasis in the South East Asian were described 30 years ago but the existence of a particular species in this area: Schistosoma mekongi has been discussed for a long time. During the last few years, emigration of Laotian and Cambodian people allowed a better knowledge of this affection. Through recent literature the authors make a restatement of the epidemiology, biology and treatment of this disease.

Animals↗
PubMedDate not supplied

[Carbohydrate-deficient transferrin and liver diseases. Study of 94 patients].

OBJECTIVES AND METHODS: Carbohydrate-deficient transferrin has been proposed as a marker of alcohol consumption. The aim of this study was to evaluate the accuracy of the carbohydrate-deficient transferrin serum level, measured by ion exchange chromatography followed by radioimmunoassay (Kit CDTect), for the diagnosis of excessive alcohol intake in patients with liver diseases. Ninety-four patients (68 men, 26 women, age 21-71 years), 42 with alcoholic liver diseases and 52 with non-alcoholic liver diseases, were studied. Twenty-six patients consumed > or = 40 g alcohol per day (mean alcohol intake: 84 +/- 52 g per day) and were considered to be excessive drinkers. RESULTS: The sensitivity of carbohydrate-deficient transferrin for the diagnosis of excessive alcohol intake was 35%, and the specificity was 91%. By pairing carbohydrate-deficient transferrin with other markers of alcohol consumption, the sensitivity of the association of carbohydrate-deficient transferrin and gammaglutamyl transpeptidase was 96%, and the specificity was 59%. CONCLUSION: In patients with liver diseases, carbohydrate-deficient transferrin is a specific marker of excessive alcohol intake but a lack of sensitivity may limit its use.

Adult↗
PubMedDate not supplied

[Spontaneous reactivation of the hepatitis B virus?].

The authors present 4 cases of chronic AgHBs positive hepatitis, with reactivations of hepatitis B virus. The reactivations occurred spontaneously, as mentioned in references. The authors appreciate that the cause of B virus reactivation bases upon factors which modify the immune status of the host. Alcohol is one of these factors, not yet mentioned in references as cause of virus B reactivation. Are also presented data about the existence of virus B mutants, in the studied patients, which could play a role in the reactivation of chronic hepatitis B.

Adult↗