Biomedical subjects

Y Baba

Publications and source records attributed to Y Baba.

455 records · Page 26Linked to original sources

PubMedDate not supplied

MR imaging of lingual carcinoma: comparison with surgical staging.

The purpose of this study was to determine the usefulness of magnetic resonance (MR) imaging for the preoperative staging of 18 patients with lingual carcinomas. Tumor stage as determined by MR imaging was compared with pathological stage. Conspicuity of tumors was compared among dynamic MR, T2-weighted, and postcontrast T1-weighted images. The tumor stage was evaluated correctly with MR imaging in 15/18 patients (83.3%). One patient was overstaged and two understaged due to incorrect diagnosis of size. In all T4 cases, tumor extension was diagnosed correctly. Dynamic MR and T2-weighted images were superior to postcontrast T1-weighted images in delineating and showing the extension of carcinomas. However, dynamic MR imaging showed no significant superiority to T2-weighted imaging. We conclude that MR imaging is of great value in the staging of lingual carcinoma. Dynamic study should be performed only when the lesion is undetectable or equivocal on T2-weighted imaging.

Adult↗

PubMedDate not supplied

Azelastine: its clinical application for radiation dermatitis.

A retrospective analysis was performed to investigate the radioprotective effects of azelastine against radiation dermatitis for patients with head and neck cancers. The effects of azelastine were studied in 19 patients with laryngeal cancers treated by irradiation. As controls, 29 patients with laryngeal cancers treated by irradiation without the administration of azelastine were studied. All patients were irradiated using 3 MV linac X-rays. Azelastine was administered orally twice a day. Moist desquamation was observed in four of 29 control patients whereas no such moist desquamation developed after the administration of azelastine. Two cases of moist desquamation that developed before the administration of azelastine regressed during irradiation in patients placed on azelastine. Radiotherapy was completed without interruption in all patients treated with azelastine. No severe side effects were observed. Azelastine, administered orally, was a safe drug and has the potential of improving skin tolerance in irradiation therapy.

Anti-Inflammatory Agents, Non-Steroidal↗

PubMedDate not supplied

A case of retroperitoneal pseudomyxoma.

We experienced a rare case of pseudomyxoma that progressed into the retroperitoneum. This patient presented with complaints of polyuria and back pain. CT and MRI showed a retroperitoneal cystic tumor. Surgical and pathological findings confirmed mucinous cystadenoma of the appendix that reached the posterior space behind the right kidney through the retroperitoneum.

Appendiceal Neoplasms↗

PubMedDate not supplied

External radiation therapy of prostatic carcinoma and its relationship to hormonal therapy.

From 1980 to 1990, a total of 54 patients with prostatic carcinoma were treated with external radiation therapy at the Kumamoto National Hospital. Ten patients were classified as Stage B, 22 as Stage C, and another 22 as Stage D according to the American Urological Association Clinical Staging System. The 5-year survival for all 54 patients was 30%. The 5-year disease-specific survival was 67% for Stage B, 47% for Stage C, and 26% for Stage D. The 5-year survival was 43% for patients in whom radiation therapy was initiated immediately after the first diagnosis or with less than one year of hormonal therapy, while it was 0% for patients in whom radiation therapy was initiated after more than one year of hormonal therapy (p = 0.01). The cause of intercurrent death was acute myocardial infarction in four patients and acute cardiac failure in one. Four of these patients received hormonal therapy for more than one year. The incidence of radiation-induced proctitis was not severe. This study suggests that long-term hormonal therapy prior to radiation therapy worsens the prognosis of patients with prostatic carcinoma.

Aged↗

PubMedDate not supplied

Osseous primitive neuroectodermal tumor--a case report.

PNET and Ewing sarcoma are pathologically distinct entities with very similar clinical and radiological characteristics. Immunohistochemical studies are needed to distinguish PNET from Ewing sarcoma, with the former being characterized by neural differentiation. We present the case of a 17-year-old man with immunohistochemically confirmed PNET in the cervical vertebrae.

Adolescent↗