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Biomedical subjects

Y Baba

Publications and source records attributed to Y Baba.

At least 379 records · Page 21Linked to original sources

Ovulation induced by synthetic luteinizing hormone-releasing hormone in the hamster.

A synthetic decapeptide, corresponding to the chemical structure of luteinizing hormone-releasing hormone from porcine hypothalami, was tested for the induction of ovulation in golden hamsters that had previously been treated with phenobarbital to prevent spontaneous ovulation. Subcutaneous injection of 0.089 to 0.357 nanomole of this synthetic luteinizing hormone-releasing hormone stimulated release of luteinizing hormone and induced ovulation.

Animals↗

Gonadotropin-releasing hormone: one polypeptide regulates secretion of luteinizing and follicle-stimulating hormones.

A polypeptide isolated from porcine hypothalami stimulates the release of both luteinizing hormone and follicle-stimulating hormone from the pituitaries of several species. This polypeptide has been structurally identified as (pyro)Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH(2) and synthesized. The natural and synthetic materials share biological properties. It appears that this peptide represents the hypothalamic hormone regulating the secretion of both luteinizing hormone and follicle-stimulating hormone.

Amino Acid Sequence↗