[Posterior luxations of the elbow in children].
Explore the source record for details and available documents.
Adolescent↗
Biomedical subjects
Y Aubard
Publications and source records attributed to Y Aubard.
Magnetic resonance imaging of the pelvic floor.
Magnetic resonance imaging is a novel noninvasive imaging modality for the assessment of pelvic floor dysfunction. It relies on static sequences with a high spatial resolution to study muscle morphology (levator ani) and fast imaging dynamic sequences during contraction, rest, and straining. Prolapse of the various pelvic compartments is detected with respect to organ position relative to the pubococcygeal line during dynamic phases. Compared with clinical examination, its input appears to be especially invaluable in the posterior compartments (peritoneal and digestive) and to assess complex prolapses involving more than one pelvic compartment. It is also useful for understanding postsurgical recurrences.
Female↗
Transplantation in reproductive medicine: previous experience, present knowledge and future prospects.
The use of transplantation in reproductive medicine has been considered by physicians and scientists alike for many years. Despite being side-tracked into futile pursuits of rejuvenation in the early days, the possibility of usefulness remains, particularly for preserving fertility in patients undergoing ablative chemo- or radiotherapy. These aims have been enhanced by advances in tissue cryopreservation. When isolated primordial follicles are transferred in the mouse, or ovarian tissue slices are grafted into sheep, it is possible to obtain follicular survival with subsequent maturation and oestrogen secretion and even restore fertility to sterilized hosts. For preservation of fertility, autografts avoid both the immunological problems of allografts and the ethical dilemmas when using donor tissue. In the male, the concept of spermatogonial cell transfer after isolation and frozen storage of cells recovered from a testicular biopsy is most attractive, since it may provide another option for rescuing fertility in cancer patients, and provide a much needed one in children. Recent results demonstrate that gonocytes from immature mice injected into the tubules of sterilized hosts restore spermatogenesis and produce fertile spermatozoa. Furthermore, the gonocytes can be stored frozen prior to transfer and still produce fertile tubules. This review presents a broad history of transplantation in the male and female genital tracts as well as attempts to anticipate possible future developments.
Animals↗
Primary fetal hydrothorax: A literature review and proposed antenatal clinical strategy.
OBJECTIVE: To investigate the prognostic factors for primitive fetal hydrothorax (PFHT) and propose a clinical strategy based on systematic literature review. METHODS: We reviewed 64 articles describing 204 cases of PFHT. For each case we focused on 11 criteria. We investigated prognostic factors in the 89 cases where no in utero treatment was undertaken. We also studied the impact of different in utero treatments on the evolution of PFHT. RESULTS: We have found 4 factors correlated with the course of PFHT: the presence of hydrops, gestational age at time of birth, the unilateral or bilateral nature of the effusion, and the occurrence of spontaneous resolution. With multivariate analysis, only hydrops remained determinant as a prognostic factor. CONCLUSIONS: Studies such as ours, reviewing case reports or series, are subject to the biases of literature underreporting of therapeutic failures or nonintervention. However (with the best available data) we propose a clinical approach to PFHT discovered in utero.
Female↗
A rare cause of fetal ascites: A case report of Günther's disease.
Despite an arsenal of ever-improving diagnostic tools, determining the precise etiology of fetal ascites is not always possible. We report a case history where moderately-severe fetal ascites was retrospectively determined to be due to Günther's disease (congenital erythropoietic porphyria). The infant was found to carry the mutation associated with the most severe disease phenotype in which fetal hydrops has been described.
Adult↗
[Value of Tissucol in cervical anastomosis of esophagoplasty].
There is an important fistula rate associated with the cervical anastomosis of oesophagoplasties. The authors report their experience with reinforcement of these anastomoses by adhesion using a fibrinogen based biological tissue glue. They propose that this technique be used in all high risk anastomoses, in particular, for those affecting a non peritonealized section of the digestive tract.
Anastomosis, Surgical↗
[Indications for the cryopreservation of ovarian tissue. Study Group for the Cryopreservation of Ovarian Tissue].
A number of questions should be envisioned before proposing the indications for clinical use of ovarian tissue cryopreservation (OTC). With what goal is ovarian tissue being preserved? To protect ovarian function which includes the ovarian endocrine secretions and the monthly release of a mature oocyte assuring the fertility of the patient; preservation of fertility is in fact the key goal. To whom should OTC be offered? In theory, to all women whose ovarian function is threatened in a physiological, pathological or iatrogenic manner. In practice, the threat to the follicular reservoir occurring with cancer chemotherapy is the best established indication. Other indications may in the future also be deemed appropriate-when human clinical use of OTC will have proven itself effective. For the present, it is preferable to reserve OTC use to patients under 35 years old who, in whatever manner, would have undergone a very severe cutback of their follicular reserve. What quantity of ovarian tissue should be extracted? It seems to us preferable to only remove one ovary, thereby leaving the patients with the possibility of undergoing spontaneous fertility, so that the frozen tissue need only be used if the ovary left in place should lose its function. How should use of the frozen tissue be directed? Among the three theoretic possibilities: of tissue autograft, follicular maturation in vitro, and heterograft, only the autograft appears realizable in the near future. However, presently, pregnancies using this technology have only been obtained in three animal species. For the near future, it appears to us that resort to OTC must remain infrequent and only performed in the setting of clinical research protocols. Priority should be given to continued basic research as many key points of OTC practice still need to be clarified.
Cryopreservation↗