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Biomedical subjects

Y Anavi

Publications and source records attributed to Y Anavi.

At least 37 records · Page 2Linked to original sources
PubMed1990

Primary malignant melanoma in the parotid gland.

Reports of primary malignant melanoma arising from the parotid salivary gland are extremely rare and, to date, have been sporadic. We report a pertinent case, and tabulate and correlate the clinical findings of the 13 cases reported thus far in the literature. The most common symptom is a progressively enlarging, asymptomatic, firm, and fixed mass. Total excision has been the established treatment of choice. The contribution of radiotherapy, chemotherapy, and immunotherapy remains unclear, and it is not possible at present to predict the outcome of treatment in individual patients. Although rare, primary malignant melanoma should be considered in the differential diagnosis of parotid tumors. The clinical significance of establishing the diagnosis of primary malignant melanoma of the parotid gland is emphasized.

Adult↗
PubMed1990

Head, neck, and maxillofacial childhood Burkitt's lymphoma: a retrospective analysis of 31 patients.

Thirty-one children with Burkitt's lymphoma of the head, neck, and maxillofacial region diagnosed between 1976 and 1988 were reviewed. The age range was 2 to 17 years (median, 7.2 years), and 77.4% were males. The most common presenting symptoms were detectable masses, floating and/or painful teeth, enlarged cervical lymph nodes, sore throat, and neurologic signs. The predominant primary tumor sites were the jaws and tonsils. All patients were staged by a clinical staging system, 17 of them having stage I-II, and 14 stage III-IV. Levels of lactate dehydrogenase and ferritin were the only significant laboratory parameters correlating with initial staging and disease-free survival. Radiologic features in the jaws were poorly circumscribed destructive lytic lesions with migration and crypt destruction of unerupted teeth buds. Complete disappearance of these findings was noted after successful chemotherapy and clinical regression of the tumor. Eighteen (58.1%) patients attained complete remission with a follow-up of 5 to 100 months. Stage was the most significant variable affecting outcome, with 90.2% disease-free survival of stage I patients, 72.4% of stage II, and 18.2% of stage III-IV. Based on these results, it is concluded that localized (stage I and II) Burkitt's lymphoma is responsive to chemotherapy and thus has a favorable prognosis.

Adolescent↗
PubMed1990

Peripheral ameloblastoma of the gingiva. A case report.

Reports of gingival peripheral ameloblastoma are extremely rare and have been sporadic. This paper reports a pertinent case of a 40-year-old woman who for 2 years had a progressively enlarging asymptomatic firm mass in the buccal gingival region of the lower premolars. Cupping of the underlying bone was radiographically demonstrated. The lesion was excised surgically together with extraction of the first premolar, and no evidence of recurrence was seen 5 years later. The clinical, radiological, and histopathological characteristics of gingival peripheral ameloblastoma were analyzed in the 33 previously reported cases. The differential diagnosis and treatment of this case report are discussed.

Adult↗
PubMed1990

Prader-Labhart-Willi syndrome.

Prader-Labhart-Willi Syndrome is a complex, multisystem sporadic disorder which presents during childhood and proceeds into adulthood. The major features include infantile hypotonia, developmental delay, hypogonadism with abnormal sexual maturation, mental retardation and behavior abnormalities, short stature with small hands and feet, massive obesity with diabetes mellitus, dysmorphic facial features, and marked dental caries and enamel hypoplasia. Recently, a deletion of chromosome 15 has been found in a large percentage of these patients, but the exact cause and genetic transmission has not yet been determined. Two cases of Prader-Labhart-Willi Syndrome are presented with emphasis on the differential diagnosis of enamel hypoplasia associated with sexual maturation.

Adult↗
PubMed1990

Sarcoidosis with oral involvement.

A case of sarcoidosis with bilateral hilar lymphadenopathy and multiple submucosal papular oral mucosa lesions is presented. The clinical signs and symptoms described in this case are not uncommon, and their distinguishing features may expedite accurate diagnosis. Early incisional biopsy of the oral mucosa appears useful for histopathologic proof of the diagnosis.

Acute Disease↗
PubMed1989

Malignant fibrous histiocytoma of the mandible.

Malignant fibrous histiocytoma of the mandible has appeared frequently enough in the world literature in recent years to assume a legitimate place in the differential diagnosis of neoplastic masses of the lower jaw. This article reports a pertinent case and tabulates and correlates the findings of all cases reported thus far. The report also explores the contribution of immunohistochemistry to proper diagnosis and emphasizes the advantages of a cojoint effort between surgeon and pathologist at the time of initial patient evaluation. The case reported also demonstrates the poor prognostic characteristics of this lesion and the uncertainty as to proper mode of treatment.

Adolescent↗
PubMed1988

Squamous cell carcinoma arising in an odontogenic cyst.

Squamous cell carcinoma arising is an odontogenic cyst is rare, Eversole finding 36 cases in his review of the literature in 1975. Since then, a further 10 have been recorded in the English literature. We now report another case and describe its management. The need to histologically examine all odontogenic cysts is stressed.

Carcinoma, Squamous Cell↗
PubMed1981

Dental extractions during anticoagulant therapy.

1. 15 patients, whose therapy with the anticoagulant Coumarin was not discontinued, were observed for bleeding following dental extractions. 2. There was no significant bleeding in these patients as compared to 15 others whose Coumarin therapy was temporarily interrupted. 3. Patients with prosthetic heart valves should preferably be hospitalized for dental extractions. but Coumarin/anticoagulant therapy need not be discontinued. The procedures can safely be done within a therapeutic range of 20-30% P.T.

Adult↗
PubMed1979

Local reaction to gingival injections of MER/BCG in guinea pigs.

The local reaction to gingival injections of methanol extraction residue of BCG (MER/BCG) was investigated in guinea pigs to help determine the potential of this agent in treating oral carcinoma. The drug was used in a standard and diluted form. Both concentrations were well tolerated and caused no ulceration or necrosis. Histological examinations performed at predetermined intervals showed an inflammatory response to the standard and the diluted solution. This reaction was more pronounced when the higher concentration was used. No changes in the alveolar bone were found in either of the groups. Complete healing with scar formation was evident four to six weeks later. The absence of severe reactions after injections of MER should encourage further investigations of this agent in the local treatment of neoplastic processes in the oral cavity.

Animals↗
PubMed1976

Salivary IgA and serum IgG and IgA in recurrent aphthous stomatitis.

Salivary flow rate and sIgA were measured in twenty-one patients suffering from recurrent aphthous stomatitis (RAS). Out of this group ten volunteered for continuous study. In these patients salivary IgA and serum IgA and IgG were measured every 3 days for 3 weeks. All parameters were in the physiologic range of healthy people. No correlation with the clinical condition of the patients was found.

Adolescent↗