Molecular biology of carcinogenesis. II. Complementarity between cell and virus nucleic acids in viral carcinogenesis.
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Biomedical subjects
Publications and source records attributed to Y Alvarez.
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OBJECTIVES: To describe how nurses assess and manage pain in critically ill children. DESIGN: Descriptive, comparative research design, with use of the Indicators of Pain in Critically Ill Children assessment tool. SETTING: Twelve-bed pediatric intensive care unit in a metropolitan general hospital with a level II pediatric trauma center. PARTICIPANTS: Twenty-four pediatric intensive care unit nurses who conducted 112 assessments of 25 critically ill children. RESULTS: Pain indicators selected most frequently by nurses included cardiovascular and respiratory changes (increased heart rate, respiratory rate, and blood pressure), followed by behavioral indicators (irritable/fussy, verbalizing pain, crying), and neuromuscular responses (tenseness/rigidity, squirming, drawing up legs). The average number of pain indicators selected during each medication event was 5.3. More indicators were selected for trauma, surgery, and younger patients; fewer indicators were selected for patients receiving ventilation treatment. CONCLUSION: Pain assessment of critically ill children includes unique indicators, as compared to less sick children, and must take into account the child's decreased ability to communicate pain.
Testudo graeca is an endangered species of tortoise that inhabits Mediterranean areas of Africa, Asia, and Europe. Western populations are found on both sides of the Straits of Gibraltar. The effects of geographical isolation on genetic divergence were assessed by the sequence analysis of two mitochondrial DNA regions of the 12S rRNA and cytochrome b genes. Four different haplotypes were identified. A single haplotype was shared by all Spanish and some east Moroccan specimens. Two haplotypes were unique to the west Moroccan T. graeca populations and allowed the clear discrimination between individual specimens found west of the Moulouya River. Phylogenetic analysis based on the estimation of nucleotide sequence distances of the haplotypes suggests an African origin for the Spanish populations and a subspecies status for the west Moroccan pool.
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