Search PubMed⌕ Search

Biomedical subjects

Y Akagawa

Publications and source records attributed to Y Akagawa.

At least 73 records · Page 4Linked to original sources

The three-dimensional bone interface of an osseointegrated implant: a method for study.

To clarify the three-dimensional bone structure around a plasma-sprayed hydroxyapatite-coated endosseous dental implant, bone contact with the implant at 75 microns intervals was evaluated. Based on digitized data, three-dimensional graphics of the bone around the implant was clearly shown. These graphics provide adequate information on the bone-implant interface and also suggest development of a realistic finite element model.

Animals↗

Clinical evaluation of the gingiva around single-crystal sapphire endosseous implant after experimental ligature-induced plaque accumulation in monkeys.

This study was performed to evaluate clinical changes of the gingiva with plaque accumulation around the single-crystal sapphire implant. Four implants were inserted into mandibular and maxillary edentulous regions, and the superstructure was inserted 1 month after insertion of the implants in each of nine monkeys. Plaque control was maintained for 3 months after insertion to set up the baseline. Plaque was allowed to accumulate on one side by placing the ligature around the implant and natural teeth without any plaque control, and on the other side plaque control was continued for 9 months. Both the implant and natural teeth on the ligature side showed a significant increase in the clinical parameters of plaque index, gingival index, and probing depth. No significant difference was obtained between the implant and natural teeth. These findings indicate that plaque control is of great importance for maintaining the health of peri-implant gingiva.

Aluminum Oxide↗

Tissue compatibility and stability of a new zirconia ceramic in vivo.

Tissue reaction and stability of partially stabilized zirconia ceramic in vivo was evaluated with the use of the subcutaneous implantation test. During the experimental period, zirconia ceramic was completely encapsulated by a thin fibrous connective tissue with less than 80 microns thickness. No changes of weight and 3-point bending strength were detected after 12 months of implantation. The result suggests that zirconia ceramic is biocompatible and no degradation of zirconia ceramic occurred.

Aluminum Oxide↗

Antifungal drugs affect adherence of Candida albicans to acrylic surfaces by changing the zeta-potential of fungal cells.

The effect of sub-inhibitory concentrations of antifungal drugs on the adherence of Candida albicans to acrylic surfaces was investigated. Among five antifungals tested, azalomycin F and aculeacin A significantly enhanced the adherence. The zeta-potential of fungal cells was affected by antifungal drugs, whereas no significant change in cell surface hydrophobicity was observed. The relationship obtained between the change in the adherence and that in zeta-potential suggests that the enhanced adherence was caused by decreased electric repulsive forces.

Acrylates↗

Prevention of acquired immunodeficiency syndrome and hepatitis B. Part III: Disinfection of hydrophilic silicone rubber impression materials.

The effect of glutaraldehyde solution, an effective disinfectant for viruses, on the dimensional stability of hydrophilic silicone rubber impression materials was evaluated in this study. Disinfection with 2% glutaraldehyde solution showed a slight expanding effect on the dimensional stability of the hydrophilic silicone rubber impression materials (less than 0.03%). It was revealed that glutaraldehyde can be used for the disinfection of hydrophilic silicone rubber impression materials. Attention should be paid, however, to the conditions for investment or casting to eliminate the expanding effect of this disinfecting procedure.

Acquired Immunodeficiency Syndrome↗

Initial interface between submerged hydroxyapatite-coated titanium alloy implant and mandibular bone after nontapping and tapping insertions in monkeys.

To clarify whether direct bone interface of submerged plasma-sprayed hydroxyapatite-coated implants could be achieved by nontapping insertion, histologic and histometric studies were made on the structure of the interface between the implant and the mandible in two monkeys. All hydroxyapatite-coated implants, whether by nontapping or tapping insertions, were healed with direct bone apposition. No histologic and histometric difference of interface structure was observed between nontapping and tapping insertions.

Alloys↗

Prevention of acquired immunodeficiency syndrome and hepatitis B. Part IV: The effect of impression material on glutaraldehyde solution.

Immersion of dental impressions in 2% glutaraldehyde has been shown to be an effective disinfection procedure for viral contamination. This study compared the effect of immersing impression materials on the concentrations of glutaraldehyde. Contamination with saliva slightly affected the concentration of glutaraldehyde. Irreversible hydrocolloid impression material markedly decreased the concentration of glutaraldehyde, whereas the immersion of silicone rubber impression material only slightly affected the concentration of glutaraldehyde. Attention should be paid to the concentration of glutaraldehyde solution when irreversible hydrocolloid impression material is immersed in the disinfectant.

Acquired Immunodeficiency Syndrome↗

[A study on mandibular incisal point movement of TM disorder patients].

In order to establish diagnostic and treatment system for temporomandibular (TM) disorder patients, data were collected on mandibular border and tapping movements at incisive point and compared with those from the subjects without any TM disorders. Significant differences on the ratio of left and right sides of maximum lateral deviation, maximum opening amount and length of pathway of lateral border movement were clearly obtained, the values of maximum speed and acceleration of closing phase in tapping movement obtained from TM disorder patients were also different significantly from those in the control subjects. These findings suggests that those measured indices in this study would be useful for diagnosis of TM disorders.

Dental Occlusion↗

[A study of the effectiveness of denture cleanser on human breath].

The purpose of this study is to measure the human breathes of denture wearers by using breath sensor, and to evaluate the influence of denture cleansing. The following results were obtained. 1. There is a possibility that the human breathes of full denture wearers may originate from their dentures. 2. There is a possibility that the cleansed dentures may cover the smell of the patient's oral mucosa itself and may reduce the apparent human breathes. Anyhow, the human breathes of denture wearers reduce significantly by using the denture cleanser.

Breath Tests↗

An evaluation of chewing function of complete denture wearers.

Chairside scoring of chewing function of complete denture wearers has been difficult. This study presents a table for chairside evaluation of the chewing function of Japanese complete denture wearers. The concept can be effective in other countries and permit international comparisons among complete denture wearers.

Aged↗

A short-term evaluation of the effectiveness of stabilization-type occlusal splint therapy for specific symptoms of temporomandibular joint dysfunction syndrome.

To clarify the short-term effectiveness of stabilization-type occlusal splint therapy, a specific symptom approach was used toward 30 temporomandibular joint dysfunction patients with more than two major symptoms (temporomandibular joint and/or masticatory muscle pain, temporomandibular joint sounds, and limitation of mandibular movement). Eighty-seven percent of the patients with pain responded with this therapy and more than 50% had complete relief of pain 4 weeks after insertion of the splint. Temporomandibular joint sounds and limitation of mandibular movement responded more slowly than pain. These results suggest that the stabilization-type occlusal splint should be selected as a first choice among several therapies and that temporomandibular joint pain is particularly susceptible to this therapy.

Acrylic Resins↗

Ultrastructure of the peri-implant junctional epithelium on single-crystal sapphire endosseous dental implant loaded with functional stress.

To elucidate the ultrastructure of peri-implant junctional epithelium (IJE) on single-crystal sapphire dental implants connected to the adjacent teeth by a metal superstructure, the peri-implant gingivae of ten monkeys were examined using a transmission electron microscope (TEM) at 3, 6 and 12 months after implant insertion. At the time of examination, the ultrastructural features of the IJE were almost identical to those of junctional epithelium (JE) attached to natural teeth, i.e. developed Golgi complexes, rough-surfaced endoplasmic reticulum, numerous free ribosomes and mitochondria. The innermost cells of IJE were attached to the implant surface by means of basal lamina-like structures (500-1000 A in thickness) and hemidesmosomes, but lacked a dental cuticle as seen on teeth. Such epithelial attachment of the IJE was often indistinct or absent at the apical portion of the IJE which terminated at the level of alveolar crest. A continuous basal lamina-like structure was also present along basal cells at the interface between the IJE and gingival connective tissue except at its apical portion.

Aluminum↗

Correlation between clinical and histological evaluations of the peri-implant gingiva around the single-crystal sapphire endosseous implant.

The correlation between clinical periodontal parameters and histological structure of the gingiva around a single-crystal sapphire implant has been evaluated in two volunteer subjects. The implants had functioned after 6 years as the distal abutment of implant bridges in the Kennedy class II mandible. First, clinical evaluation was performed (gingival bleeding index, crevicular fluid volume, plaque index and probing depth) of the gingiva around the implant and natural teeth abutments and then a small piece of peri-implant gingiva was excised from the lingual site of the implant of each subject for histological evaluation. The clinical evaluation using the periodontal parameter indices corresponded with the histological evaluation of the peri-implant gingiva. The result suggests that it is possible for such parameters to be used in practice for judging the success of an implant.

Adult↗

[Electromyographic study on masticatory function of the telescope denture wearers in the Kennedy Class II mandible].

Masticatory function of 10 telescope denture wearers in the Kennedy class II mandible patients was evaluated with electromyography. Electromyographic activity during mastication with kamaboko and peeled raw carrot was recorded from bilateral masseter and the anterior part of temporal muscles at each interval: Before treatment, immediately after denture insertion and 2, 4, 6, 8 weeks after respectively. Mean of duration, interval and cycle of EMG activities, coefficient of variation and average variation were calculated. The results were as follows: 1. Means of duration and cycle times decreased immediately to 2 weeks after denture insertion. 2. EMG activities during raw carrot chewing became regular immediately to 2 weeks after denture insertion, and within 4 weeks in kamaboko chewing. These results suggest that telescope dentures would be adapted to stomatognathic system within short period after denture insertion.

Denture, Overlay↗

Comparative evaluation of chewing function with removable partial dentures and fixed prostheses supported by the single-crystal sapphire implant in the Kennedy Class II partially edentulous mandible.

Differential chewing function with removable partial dentures (RPDs) and fixed prostheses supported by the single-crystal sapphire implant was evaluated in five subjects with Kennedy Class II partially edentulous mandibles by means of electromyography. Rehabilitation with the single-crystal sapphire implant resulted in regular chewing patterns with a low variation coefficient and higher activity of chewing-side masticatory muscles compared to RPD rehabilitation. This difference in chewing function between the two rehabilitation modalities could be the result of differences in stability of occlusion and neurophysiologic feedback systems.

Aluminum Oxide↗