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PubMed2005

Clinical observation on juvenile macular hole without trauma and hypermyopia.

PURPOSE: To investigate the clinical characteristics of juvenile macular hole without trauma and hypermyopia, and research the mechanism of macular hole. METHODS: Sixty-seven patients less than 40 years of age were studied retrospectively from June 1998 to March 2003. Five cases (7 eyes) aged from 22 to 38 years were reported and the clinical characteristics that had macular hole without trauma or hypermyopia were summed up. RESULTS: There was 1 male and 4 females with visual acuity from 0.08 to 0.8. The images of optical coherence tomography (OCT) showed full thickness macular hole in 5 patients (7 eyes), and the diameters were from 87 to 1043 microm. Among them, 2 cases were combined with retina pigmentosa; 1 case with binocular Coat's disease; 1 case had bilateral macular hole combined with Eagles' disease; 1 case was combined with 2-2.5PD old retinochoroidal lesion under middle-peripheral fundus, and 1.5 PD retinal pigment epithelium (RPE) defect on the optical disk. CONCLUSION: The juvenile macular hole without trauma and hypermyopia combined the different retina vascular damages and the RPE defects.

Adult↗

PubMed2002

[Contrast sensitivity function in myopic LASIK].

OBJECTIVE: To evaluate near contrast sensitivity function before and after myopic laser in situ keratomileusis (LASIK). METHODS: With FACT 101 test chart, static near contrast sensitivity was measured in randomly selected 47 subjects (93 eyes) before, 1 month and 6 months after LASIK. The contrast sensitivity was measured at 1.5, 3.0, 6.0, 12.0 and 18.0 cycles per degree (c/d) spatial frequency respectively and made comparison in them. RESULTS: The patients achieved the mean uncorrected visual acuity (UCVA) of 1.07 +/- 0.18 and 1.12 +/- 0.20 at postoperative 1-month and 6-months respectively. There was a general reduction in near contrast sensitivity in all spatial frequencies at postoperative 1-month when they were compared with the preoperative contrast sensitivity. The difference at 12 and 18 c/d spatial frequency was statistically significant (t test, P < 0.01). By the 6-month visit, all eyes showed a recovery of static contrast sensitivity function. The group of high myopia (preoperative > or = -6.00 D) and group with complaining of glare and halos after the surgery had a higher decrease rate of contrast sensitivity compared with that of the group preoperative < - 6.00 D and the group of patients without such complaints respectively. The differences at 6.0, 12.0 and 18.0 c/d spatial frequency at 1-month visit was statistically significant (t test, P < 0.05). CONCLUSIONS: The contrast sensitivity function test offers a more sensitive and comprehensive measure of functional vision than does standard Snellen acuity. The near contrast sensitivity in post-LASIK patients at early stage is reduced despite normal visual acuity and this can affect the quality of vision.

Adolescent↗