Biomedical subjects

Xiang-yin Kong

Publications and source records attributed to Xiang-yin Kong.

2 recordsLinked to original sources

PubMed2005

[IRF6 gene mutation analysis in a van Der Woude syndrome family in Henan province].

PURPOSE: To investigate IRF6 gene mutation in a van Der Woude syndrome (VWS) family in Henan province. METHODS: PCR and DNA sequencing was employed to detect the mutation of IRF6.Secondary construction transformation analysis was performed using PIX-Protein Identification software. RESULTS: A CGC>TGC(r.279c-->t) transversion of IRF6 was identified in condon 6, showing complete segregation with the disease phenotypes and was resulting in changes of the secondary constructure of IRF6. CONCLUSION: VWS is caused by mutations in IRF6 gene, and IRF6 is closely related to the development of lip, palate and tooth.

Abnormalities, Multiple↗

PubMed2005

[GNU Pattern: open source pattern hunter for biological sequences based on SPLASH algorithm].

OBJECTIVE: To construct a high performance open source software engine based on IBM SPLASH algorithm for later research on pattern discovery. METHODS: Gpat, which is based on SPLASH algorithm, was developed by using open source software. RESULTS: GNU Pattern (Gpat) software was developped, which efficiently implemented the core part of SPLASH algorithm. Full source code of Gpat was also available for other researchers to modify the program under the GNU license. CONCLUSION: Gpat is a successful implementation of SPLASH algorithm and can be used as a basic framework for later research on pattern recognition in biological sequences.

Algorithms↗