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Biomedical subjects

X Q Xu

Publications and source records attributed to X Q Xu.

32 records · Page 2Linked to original sources
PubMed1986

[Chromosome study on the Tca8113 cell line derived from squamous cell carcinoma of the human tongue].

A squamous cell line, derived from human tongue carcinoma, was designated as Tca8113. Its chromosome and G-banding karyotype were studied. The chromosome number of the Tca8113 was considered as hypotriploid (58-68, 93.5%). Trisomy was commonly found in No.1, No.7, No.16, No.17 and No.18 and was observed in all (25/25) of No.7. The modal number of chromosome was always 66 in each of the nine studies made from the 7th to the 135th passage. In the analysis of unclassifiable abnormal chromosomes, an abnormally large metacentric one--M1 had an incidence of 100% (32/32). As a marker, both arms of this M1 were similar to q. of No. 5 chromosome. This implies that M1 marker chromosome may originate from the isochromosome of the long arms of No.5 chromosome. The karyotype of this Tca8113 cell line is 66XX, +1, +4, +7, +14, +15, +16, +17, +18, M1, M2, M3, M4, M5, M6, M7, M8, M9, M10, M11, M12.

Carcinoma, Squamous Cell↗
PubMed1984

Evaluation of free flaps transferred by microvascular anastomosis in oral and maxillofacial surgery.

The authors discuss indications for the use of microvascular free flaps transferred to the oral and maxillofacial region. A series of 139 cases, involving 145 free flaps, is reported over a three year period. The overall success rate for all types of flaps was 89.3%. Advantages and disadvantages of the use of various flaps are presented and suggestions are offered to avoid complications.

Adolescent↗
PubMedDate not supplied

Determination of extra renal clearance and generation rate of beta2-microglobulin in hemodialysis patients using a kinetic model.

Beta-2-microglobulin (beta2-m) has been proposed as a marker of middle molecules to assess one aspect of the efficacy of dialysis. Until now, few data have been published about extra renal (metabolic) clearance and generation rates of beta2-microglobulin, which are necessary for calculation of total clearance and mass removal of beta2-m in hemodialysis patients. We have developed a simple method to derive extra renal clearance and generation rates of beta2-m by measuring the pre and post dialysis blood concentrations of beta2-m using kinetic modeling. Ten stable hemodialysis patients were included in this study. Pre and post dialysis concentrations of beta2-m were measured during dialysis with low flux dialyzers (F6 HPS) and after 10 days switching to high flux dialyzers (F60S or Superflux). With a validated two pool model, the generation rate of beta2-m can be determined if extra renal clearance is known. Assuming the generation rate of beta2-m to be constant in each patient, the computer reiterated the calculation of extra renal clearance until the calculated generation rate was equal for both the low flux and the high flux dialyzer. Extra renal clearance was found to be between 1.97 and 4.11 ml/min (average, 3.2 ml/min). Generation rate was found in a rather narrow range between 1.63 and 2.56 mg/kg per day (average, 2.09 mg/kg per day). There was no correlation between extra renal clearance and generation rates. With this simple method, extra renal clearance and generation rates of beta2-m can be determined using data by switching hemodialysis patients from impermeable to permeable membranes.

Age Factors↗