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Biomedical subjects

X Q Pan

Publications and source records attributed to X Q Pan.

35 records · Page 2Linked to original sources

Effect of ketotifen on the ultrastructure of the erythrocytic stages of Plasmodium yoelii.

The effect on the morphology of Plasmodium yoelii of ketotifen treatment was different from that of chloroquine and other antimalarial drugs. Following administration of a low dosage of ketotifen, the parasite first developed a multilamellate pellicular complex which resembled a medullary sheath and then developed vacuoles and cavitations. The development of large multilamellate whorls consisting of a pellicular structure enclosing cytoplasm was the typical change which occurred.

Animals↗

[Determination of allopurinol in tablets and urine by oscillopolarography].

Determination method of allopurinol has been studied by the second derivative oscillopolarography. Well-defined linear relationship between concentrations and the wave height in the range 3 X 10(-7)-1 X 10(-4) mol/L and 5 X 10(-7)-1 X 10(-4) mol/L was observed, respectively, in 0.50 mol/L H2SO4 and pH 5.5 HAc-NaAc buffer. The contents of allopurinol in tablets and urine were determined. The character of the electrode reaction was explored preliminarily.

Allopurinol↗

The relation of urinary cations to blood pressure in boys aged seven to eight years.

A study on the relation between urinary cations and blood pressure was conducted in Wuhan, China. A total of 148 boys aged 7-8 years entered the study from November 23, 1984, to January 13, 1985. Seven consecutive 24-hour urine specimens were collected and blood pressure was measured on the seven successive days corresponding to urine collection. The multiple regression showed that none of the sodium, potassium, calcium, and magnesium cations was statistically significantly related to blood pressure. However, the ratio of sodium/calcium or potassium/calcium in the urine was positively correlated with systolic pressure in multivariate analysis. The results suggest that there may be a complex interaction between sodium and calcium in their effects on blood pressure, and genetic background might have some influences on the sodium/calcium (or potassium/calcium)-blood pressure relation in the 7-8-year-old boys in the study.

Blood Pressure↗

Rapid screening of monoclonal antibodies: new 'microstick' radioimmunoassay.

A new system for assaying monoclonal antibodies consisting of an 8 x 12 array of sticks which fits into a 96-well microtiter plate is described. Tests using virus specific monoclonal antibodies and virus proteins demonstrated sensitivity equivalent to the conventional microtiter plate assay. Antibody production, antigen specific antibody, and immunoglobulin isotypes could be measured under sterile conditions directly in the original fusion mixture wells and with much greater rapidity than with the microtiter plate assay.

Antibodies, Monoclonal↗