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Biomedical subjects

X Phelip

Publications and source records attributed to X Phelip.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Bone manifestations disclosing Hodgkin's disease and non-Hodgkin's malignant lymphoma. Analysis of 11 cases].

Bone localizations revealing Hodgkin's disease or non-Hodgkin's malignant lymphoma, are unusual. We are reporting 11 recent cases collected in rheumatology and haematology departments, including 4 where a comprehensive study of X-rays, scintigrams, axial tomograms and nuclear magnetic resonance imaging was performed. Review of the literature as well as our experience concerning the type of onset of the bone involvement, the clinical correlation, the imaging techniques, have led us to consider nuclear magnetic resonance as a decisive factor which should be offered at an early stage in the diagnostic approach.

Adult↗
PubMed1988

[Spinal biomechanics and the sitting position].

Our study was conducted in two stages. In a first stage, elaboration of a reliable biomechanical model for the lumbar spine, permitting to calculate for each lumbar level, for a definite posture and a given patient, the normal and tangential forces as well as the overall stresses applied to the disc, and represented by the intradiscal pressure of the nucleus pulposus and the overall stresses in the annulus fibers. This biomechanical model was constructed with the help of radiographs and formulas of forces and moments balance in comparison with a reference axis system. This biomechanical model was then used to compare stresses on the disc in various sitting positions, in order to determine an ergonomic adaptation of the sitting position at work.

Biomechanical Phenomena↗
PubMed1987

[Horton's disease and rhizomelic pseudopolyarthritis. Developmental data apropos of 95 cases].

The many common factors linking rhizomelic pseudopolyarthritis and Horton's disease prompt to compare their respective evolutions and the long-term results of their treatments. The comparative study of 28 patients with temporal Horton's arteritis, proven histologically, and 28 rhizomelic pseudopolyarthritis without arteritis on biopsy, in a total population of 95 patients, confirms the similarity of their clinical and biological signs and show a closely related evolution in the three groups. The evolution leads to a cure approximately 16.4 +/- 14 months in 41 p. cent of the cases. 34 p. cent of the patients are at an advanced stage with a mean follow-up of 37 months and relapses during the weaning period were frequent. 25 p. cent of the patients died. Most deaths occur in the first month of the disease, and occur readily in patients who have received a short treatment with steroids discontinued because of a iatrogenic accident. Cerebral vascular accidents and coronary accidents, arterial hypertension and iatrogenic gastro-intestinal ulcerations are the most frequent complications.

Aged↗
PubMed1986

[Periungual capillaroscopy in rheumatoid arthritis. Prospective study of 80 cases].

This study involved the screening for dermal microcirculatory abnormalities using periungueal capillaroscopy in a group of 80 cases of rheumatoid arthritis, so-defined in terms of ARA criteria. Excessive erythrocyte aggregation and/or pericapillary edema were detected in 74% of cases and were statistically correlated with ESR, reflecting an inflammatory syndrome. Capillary neogenesis, probably in reaction to subclinical cutaneous vascularity, was detected in 59% of cases (86% of subjects presenting extra-articular rheumatism). In 28% of cases this was accompanied by spontaneous hemorrhage, suggesting a progressive condition. Stigmata of cutaneous atrophy were present in 54% of subjects. These findings demonstrate the frequency of subclinical cutaneous damage in rheumatoid disease and suggest the possibility of the clinical usefulness of capillaroscopy, a non-invasive technic, in the follow-up of this disease.

Arthritis, Rheumatoid↗
PubMed1986

[Bone histomorphometry in monoclonal dysglobinemia. Diagnostic and prognostic value].

Data of bony histomorphometry by transiliac biopsy were studied in 35 cases of multiple myeloma and 26 cases of benign monoclonal dysglobulinemia. In a first stage, the comparison between the two groups showed an osteoclastic resorption which was significantly higher in myeloma patients in osteolytic forms as well as asymptomatic forms, showing the diagnostic advantage of this measurement in these forms of the disease. Also, the association of a preservation of the bony trabecular volume with an osteoclastic hyper-resorption was only observed in myeloma patients. In a second stage, study of the evolution of myeloma patients permitted to demonstrate the pejorative prognostic value of an intense hyper-resorption (STRO greater than or equal to 6) from a vital point of view as well as the future of the bone; patients with an initial hyper-resorption develop an osteolysis during the first year and/or a hypercalcemia during the first 24 months; the search for a correlation between these parameters of bony resorption and known prognostic factors, has proven negative except for calcemia and the level of beta 2 serum microglobulins. This fact emphasizes the advantage of a treatment toward osteoclasts associated with the classic chemotherapy of multiple myeloma.

Adult↗
PubMed1985

[Muscular ultrasonic diagnosis. Etiological approach to various backaches].

Certain cases of mechanical back pain present unusual clinical and ultrasonographic features involving the posterior lumbar muscle groups, which can be used to distinguish various types. The clinical examination may isolate a juxta-vertebral territory in which pressure triggers or exacerbates the back pain; anaesthesia of this territory is accompanied by pain relief. Ultrasonography may reveal a hypoechogenic area in this muscle territory in which histomorphometric and ultrastructural studies, performed in three cases, revealed endomysial and perimysial adiposis associated with atrophy probably due to peripheral neuropathy.

Adipose Tissue↗
PubMed1983

[Acupuncture and sciatica in the acute phase. Double-blind study of 30 cases].

Responses to acupuncture were studied in 30 patients with acute sciatica. Objective and subjective criteria were analyzed before treatment and after five sessions of acupuncture. The study was double blind. Patients were randomly assigned to one of two groups: 15 were treated on electrically detected points and 15 on "placebo" points. In the "placebo" group, no significant improvement was recorded. Conversely, in the treated group, study of objective criteria showed improvement of the Lasegue sign. Among subjective symptoms, positive responses were recorded in the duration of improvement, degree of improvement in decubitus and after ten minutes standing, and use of analgesics. Compared to the "placebo" group these changes are statistically significant.

Acupuncture Therapy↗