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Biomedical subjects

X H Hu

Publications and source records attributed to X H Hu.

28 records · Page 2Linked to original sources
PubMed1991

[The mongoloid nose].

The more precise term "mongoloid" should be used in the place of "oriental" and "asian". The nose of the Han race constitutes the most typical example. The description of "intermediary", usually used to describe this nose is insufficient, as it has a very particular type which contributes to the "Asian triad". A study conducted by Chengdu tries to overcome this deficiency. This information is particularly useful in that aesthetic rhinoplasty, performed increasingly frequently for this type of nose, raises specific problems and requires particular caution to avoid excessive correction which may be disastrous in a small face.

Asian People↗
PubMed1990

[Endoscopic microwave treatment of 53 cases with esophageal and cardiac cancer].

Fifty-three cases with moderate or advanced esophageal and cardiac cancer treated by endoscopic microwave therapy are reported. The results showed that after 2 to 4 treatments, dysphagia was relieved in 52 (98%), esophageal re-expansion was seen in 48 (90%). Improvement was most pronounced in lesions predominantly shown as localized polypoid projection type. Biopsy after treatment was confirmed pathologically as necrosis in 24 cases. After treatment, the follow-up of 22 cases for over 3 months and 8 cases for over 6 months was carried out. 22/22 could maintain the therapeutic effectiveness and 5/8 were on soft diet (noodles and steamed bread). Microwave therapy is a palliative measure that can definitely improve the dysphagia in short term courses and prolong the survival. Microwave endoscopy, being easy in manipulation without complications, is very useful in the treatment of esophageal and cardiac cancers contra-indicated for surgery.

Adenocarcinoma↗
PubMed1986

Toxicity of dipterex: a field study.

This study summarises historical surveillance data collected from 1977 to 1982 and the results of a field study conducted thereafter (1983-4) in a dipterex packing workshop. The findings suggest that both airborne dipterex and dermal contamination contribute to the inhibition of blood cholinesterase (ChE) and that cases of poisoning in hot seasons can be attributed mainly to dermal absorption. At a level of 0.5 mg/m3, dipterex is shown to lead to a mild but appreciable inhibition of ChE activity. The results also indicate that blood ChE monitoring was sensitive both for long term and short term exposed workers. As a result, the recommendation that the maximum allowable concentration for airborne exposure to dipterex be revised to 0.5 mg/m3, can be regarded at providing only for relative safety.

Air↗
PubMedDate not supplied

Lead cytotoxicity in primary cultured rat astrocytes and Schwann cells.

The cytotoxic effects of lead acetate on primary cultured astrocytes and Schwann cells (SCs) were studied for comparing the sensitivity of the two kinds of cells and exploring the possible mechanism of lead cytotoxicity. The results indicated that the number of astrocytes detached from the culture surfaces were dependent on the concentration and time of lead exposure. Under phase contrast microscopy, increases in the number of vacuoles were observed at doses of 50 and 100 micrograms ml-1 lead after 96 h of lead exposure for astrocytes and 1, 5 and 10 micrograms ml-1 lead after 24 h of lead exposure for SCs. By scanning electron microscopy, the surface changes in astrocytes began to appear at the dose of 10 micrograms ml-1 lead, whereas in SCs it began in 1 microgram ml-1 lead. By transmission electron microscopy, astrocytes exposed to 10, 50 and 100 micrograms ml-1 lead had increased lysosomal densities, the presence of nuclear inclusions and enlargement of rough endoplasmic reticulum, whereas SCs exposed to 1 microgram ml-1 lead began to show swelling of mitochondria and endoplasmic reticulum, cytoplasmic vacuolizations and numerous myelinoid bodies. Increases in the content of lactic dehydrogenase (LDH) leakage from the astrocytes exposed to 100 micrograms ml-1 lead and SCs exposed to 1, 5 and 10 micrograms ml-1 lead were observed, respectively. Decreases in sulphydryl group (SH) levels in astrocytes exposed to 50 and 100 micrograms ml-1 lead and SCs exposed to 1, 5 and 10 micrograms ml-1 lead were also observed. A dose of 1.0 mmol l-1 reduced glutathione (GSH) and 2.0 mmol l-1 dithiothreitol (DTT) could protect astrocytes from lead-induced SH decrease and LDH leakage. Doses of 10-100 mumol l-1 cAMP were shown to have a protective effect on lead-induced SH decrease in SCs. No significant changes of GSH or lipid peroxidation (LPO) were observed in astrocytes. The results indicated that SH was involved in lead-induced cytotoxicity of astrocytes and SCs, and SCs were more sensitive to lead-induced cytotoxicity than astrocytes.

Animals↗
PubMedDate not supplied

Epidural sufentanil for analgesia for labor and delivery.

Six groups of ten women each in active labor at term had epidural catheters placed in the usual manner and received a 3 mL test dose of 2% lidocaine with epinephrine. Groups 1-6 received, respectively, 5, 10, 20, 30, 40 and 50 micrograms of sufentanil diluted to 10 mL with normal saline. Significantly effective analgesia was provided at all sufentanil doses studied, with pain scores decreasing from 8.1 +/- 0.2 at baseline to 2.9 +/- 0.3 at 10 minutes and 1.1 +/- 0.2 at 30 minutes (mean +/- SEM, average for all groups). The duration of analgesia showed a significant (p less than 0.05) relation to sufentanil dose, increasing from 79.1 +/- 11.3 minutes (5-micrograms group) to 137.8 +/- 17.2 minutes (50-micrograms group). There were no serious maternal side effects, although ten patients developed pruritus, four became dizzy, two experienced mild sedation, and one had transient hypotension. No neonatal side effects occurred. Maternal serum sufentanil levels remained below the sensitivity of the assay, or 0.1 ng/ml.

Adult↗