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Biomedical subjects

William A Suk

Publications and source records attributed to William A Suk.

6 recordsLinked to original sources

The Superfund Basic Research Program--making a difference: past, present, and future.

Understanding exposure continues to be a paramount challenge and critical element in successfully managing Superfund sites. The Superfund Basic Research Program, administered by the National Institute of Environmental Health Sciences, an institute of the National Institutes of Health, is committed to providing the nation's decision makers with better tools to identify the routes and effects of exposure and develop innovative technologies to reduce exposures. In this article, we demonstrate how the program contributes to understanding the exposure disease link, highlight the cutting-edge and practical nature of this very fundamental research program and discuss its approach to addressing these problems. We also identify several broad themes that are likely to direct the program's future research endeavors.

Environmental Exposure↗

The origin, fate, and health effects of combustion by-products: a research framework.

Incomplete combustion processes can emit organic pollutants, metals, and fine particles. Combustion by-products represent global human and environmental health challenges that are relevant not only in heavily industrialized nations, but also in developing nations where up to 90% of rural households rely on unprocessed biomass fuels for cooking, warmth, and light. These issues were addressed at the Seventh International Congress on Combustion By-Products, which convened 4-6 June 2001 in Research Triangle Park, North Carolina. This congress included a diverse group of multidisciplinary researchers and practitioners who discussed recent developments and future goals in the control of combustion by-products and their effects of exposure on human and ecologic health. Participants recommended that interdisciplinary, coordinated research efforts should be focused to capitalize on the important potential synergisms between efforts to reduce the adverse human health effects linked to exposures to combustion by-products and broader efforts to reduce greenhouse gas emissions and save energy through efficiency. In this article we summarize the principal findings and recommendations for research focus and direction.

Bioelectric Energy Sources↗

Indicators of ocean health and human health: developing a research and monitoring framework.

We need to critically assess the present quality of the marine ecosystem, especially the connection between ecosystem change and threats to human health. In this article we review the current state of indicators to link changes in marine organisms with eventual effects to human health, identify research opportunities in the use of indicators of ocean and human health, and discuss how to establish collaborations between national and international governmental and private sector groups. We present a synthesis of the present state of understanding of the connection between ocean health and human health, a discussion of areas where resources are required, and a discussion of critical research needs and a template for future work in this field. To understand fully the interactions between ocean health and human health, programs should be organized around a "models-based" approach focusing on critical themes and attributes of marine environmental and public health risks. Given the extent and complex nature of ocean and human health issues, a program networking across geographic and disciplinary boundaries is essential. The overall goal of this approach would be the early detection of potential marine-based contaminants, the protection of marine ecosystems, the prevention of associated human illness, and by implication, the development of products to enhance human well-being. The tight connection between research and monitoring is essential to develop such an indicator-based effort.

Animal Diseases↗

Indicators of ocean and human health.

The interactions between humans and the ocean are significant, and necessitate more comprehensive study on an international scale. The world's oceans provide great health benefits to humans ranging from food and nutritional resources, to recreational opportunities and new treatments for human disease. However, recently, human health effects from exposure to substances present in the marine ecosystem such as synthetic organic chemicals (e.g., chlorobiphenyls, chlorinated dioxins and some industrial solvents), polycyclic aromatic hydrocarbons (PAHs), metals (both introduced and anthropogenic), marine toxins, and pathogens have been recorded and are of great concern. This paper reviews our state of knowledge of the interactions between oceans and human health and proposes indicators and a research strategy to investigate and monitor these relationships more closely. Four approaches to gathering information on indicators included here are: biomarkers; cellular pathology; physiological and behavioural responses; and changes in populations. All hold the potential to enhance our understanding of marine environmental quality and far-reaching effects on human health. Monitoring systems that include the rapid assessment of contaminants in the ecosystem and subsequent risk to human populations, with appropriate internationally distributed data bases, need to be developed and validated. Such tools would provide early detection of potential environmental threats, and enhance the ability to prevent human illness.

Ecosystem↗