Biomedical subjects

Willem B Verwey

Publications and source records attributed to Willem B Verwey.

8 recordsLinked to original sources

PubMed2005

Comparing endoscopic systems on two simulated tasks.

Endoscopes are slender instruments for performing medical procedures through small incisions or natural body orifices. Three experiments examined the performance effects of various endoscope systems when naive participants executed tasks in a bladder-like environment. The systems involved a direct endoscope, requiring the user to look through a lens at the outer part of the endoscope, and a video endoscope that picks up the image via a camera attached to the endoscope and displays it on a video monitor. The results indicate that the participants performed the tasks better with video than with direct endoscopes, and showed more transfer of practice with video endoscopic surgery from a small to a large task environment than vice versa. The optimal position of the monitor with video endoscopic surgery appeared to involve a reasonable angle relative to the operating area (45 degrees was used). Performance was less at a greater angle (90 degrees), but also at a small angle (10 degrees). It did not matter whether the monitor was located left, right or above the operating area. As performance did not fully transfer to differently sized task environments, endoscopists should initially train with task environments of different, and especially small, sizes.

Adult↗

PubMed2004

Effector dependent sequence learning in the serial RT task.

At least five earlier studies could not find effector-dependent learning in the keying version of the serial reaction time (RT) task. Experiment 1 examined whether effector-dependent learning occurs when participants practice the serial RT task with three fingers of one hand for about 1,300 sequence repetitions instead of the more common 50-100 repetitions. The results confirm that, following extended practice, sequence learning produces an effector-dependent component. Specifically, an unpracticed hand executed a practiced sequence slower than a practiced hand. However, Experiment 2 showed that effector-dependent sequence learning develops only when fingers of one hand are used, suggesting that effector-dependent sequence learning involves adjustment to the mechanical interactions between the fingers of one hand. In addition, when sequences had been practiced with one hand, mirror versions of the practiced sequences in both experiments showed moderate transfer. But when practiced with two hands no transfer to a mirrored version of the sequence was observed. This suggests that only practice with one hand produces a representation that facilitates the execution of mirror sequences. Generally, the same results were found in more or less aware participants, congruent with the idea that the effector-dependent representation and the representation allowing transfer to mirror sequences are implicit.

Adult↗

PubMed2004

Learning and production of movement sequences: behavioral, neurophysiological, and modeling perspectives.

A wave of recent behavioral studies has generated a new wealth of parametric observations about serial order behavior. What was a trickle of neurophysiological studies has grown to a steady stream of probes of neural sites and mechanisms underlying sequential behavior. Moreover, simulation models of serial behavior generation have begun to open a channel to link cellular dynamics with cognitive and behavioral dynamics. Here we review major results from prominent sequence learning and performance tasks, namely immediate serial recall, typing, 2 x N, discrete sequence production, and serial reaction time. These tasks populate a continuum from higher to lower degrees of internal control of sequential organization and probe important contemporary issues such as the nature of working-memory representations for sequential behavior, and the development and role of chunks in hierarchical control. The main movement classes reviewed are speech and keypressing, both involving small amplitude movements amenable to parametric study. A synopsis of serial order models, vis-a-vis major empirical findings leads to a focus on competitive queuing (CQ) models. Recently, the many behavioral predictive successes of CQ models have been complemented by successful prediction of distinctively patterned electrophysiological recordings. In lateral prefrontal cortex, parallel activation dynamics of multiple neural ensembles strikingly matches the parallel dynamics predicted by CQ theory. An extended CQ simulation model--the N-STREAMS neural network model--exemplifies ongoing attempts to accommodate a broad range of both behavioral and neurobiological data within a CQ-consistent theory.

Animals↗

PubMed2004

Changes in the incidental context impacts search but not loading of the motor buffer.

During a retention test, a change in the nature of the incidental contextual information present during training can have a deleterious impact on response selection by not activating particular subsets of information in memory that help direct the retrieval process. The present experiment addressed whether a change in the incidental context also impacted the completion of processes associated with loading and searching the motor buffer during motor programming. A self-select paradigm was used to describe the planning and execution of one- and four-element sequences that consisted of short and long duration key-presses. During a test phase following training, changes in the incidental contextual information impeded the search of the motor buffer. However, loading specific timing information into the motor buffer was unaffected by shifts in contexts. These data support the contention that contextual information plays a fundamental role in a broad array of movement-planning operations that involve search and retrieval type activity.

Auditory Perception↗

PubMed2003

Effector-independent and effector-dependent learning in the discrete sequence production task.

This study examined whether skill in the discrete sequence production task involves, apart from the typical effector-independent component, an effector-dependent component. To that end, 12 participants practiced two 5-key sequences, each for 1,060 trials. One group practiced with three fingers of one hand, the other group with three fingers of two hands. In a subsequent test phase, participants in both groups executed the same sequences and two new sequences with the hand configuration they had used during practice, and with the hand configuration of the other group. The results provide support for an effector-dependent component in that both groups performed the practiced sequences faster with the hand configuration they had used during practice than with the hand configuration that was new to them. In addition, the unpracticed hand configuration performed the practiced sequences faster than the new sequence, which demonstrated the effector-independent component.

Adult↗

PubMed2003

Effect of sequence length on the execution of familiar keying sequences: lasting segmentation and preparation?

The author assessed the mechanisms underlying skilled production of keying sequences in the discrete sequence-production task by examining the effect of sequence length on mean element execution rate (i.e., the rate effect). To that end, participants (N = 9) practiced fixed movement sequences consisting of 2, 4, and 6 key presses for a total of 588 trials per sequence. In the subsequent test phase, the sequences were executed with and without a verbal short-term memory task in both simple and choice reaction time (RT) paradigms. The rate effect was obtained in the discrete sequence-production task-including the typical quadratic increase in sequence execution time (SET, which excludes RT) with sequence length. The rate effect resulted primarily from 6-key sequences that included 1 or 2 relatively slow elements at individually different serial positions. Slowing of the depression of the 2nd response key (R2) in the 2-key sequence reduced the rate effect in the memory task condition, and faster execution of the 1st few elements in each sequence amplified the rate effect in simple RT. Last, the time to respond to random cues increased with position, suggesting that the mechanisms that underlie the rate effect in new sequences and in familiar sequences are different. The data were in line with the notion that coding of longer keying sequences involves motor chunks for the individual sequence segments and information on how those motor chunks are to be concatenated.

Adult↗

PubMed2002

Processing modes and parallel processors in producing familiar keying sequences.

Recent theorizing indicates that the acquisition of movement sequence skill involves the development of several independent sequence representations at the same time. To examine this for the discrete sequence production task, participants in Experiment 1 produced a highly practiced sequence of six key presses in two conditions that allowed little preparation so that interkey intervals were slowed. Analyses of the distributions of moderately slowed interkey intervals indicated that this slowing was caused by the occasional use of two slower processing modes, that probably rely on independent sequence representations, and by reduced parallel processing in the fastest processing mode. Experiment 2 addressed the role of intention for the fast production of familiar keying sequences. It showed that the participants, who were not aware they were executing familiar sequences in a somewhat different task, had no benefits of prior practice. This suggests that the mechanisms underlying sequencing skills are not automatically activated by mere execution of familiar sequences, and that some form of top-down, intentional control remains necessary.

Adult↗

PubMed2002

On the role of the SMA in the discrete sequence production task: a TMS study. Transcranial Magnetic Stimulation.

Participants practiced two discrete six-key sequences for a total of 420 trials. The 1 x 6 sequence had a unique order of key presses while the 2 x 3 sequence involved repetition of a three-key segment. Both sequences showed a long interkey interval halfway the sequence indicating hierarchical sequence control in that not only the 2 x 3 but also the 1 x 6 sequence was executed as two successive motor chunks. Besides, the second part of both sequences was executed faster than the first part. This supports the earlier notion of a motor processor executing the elements of familiar motor chunks and a cognitive processor triggering either these motor chunks or individual sequence elements. Low-frequency, off-line transcranial magnetic stimulation (TMS) of the supplementary motor area (SMA) counteracted normal improvement with practice of key presses at all sequence positions. Together, these results are in line with the notion that with moderate practice, the SMA executes short sequence fragments that are concatenated by other brain structures.

Adult↗