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Wiesław Grzesiuk

Publications and source records attributed to Wiesław Grzesiuk.

7 recordsLinked to original sources
PubMed2005

[Effectiveness of iodine prophylaxis in hypertensive patients on salt restricted diet].

BACKGROUND: Iodine prophylaxis in Poland started in 1935 however it has been interrupted during Second World War, and also in 1980. In January 1997 a new approach of preventing iodine deficiency was introduced as obligatory iodination model of household salt to be extent of 30 mg KI/kg. The aim of the study was to determine iodine intake after introduction of mandatory salt iodization in group of persons being on low salt diet because of hypertension. Investigated group and methods: The study was performed on 227 persons (94 males and 133 females), aged 18-89 years (average age 56 +/- 15,2 years). Each person answered questions concerning salt consumption and other products being additional source of iodine (fishes, pharmaceutical preparations containing iodine). Subjects were divided into two groups: according to the amount of salt consumption (119 persons restricted to household salt and 108 persons used kitchen salt) and according to the value of blood pressure (170 persons was hypertensive and 57 persons was normotensive). The urine iodine concentration (UIC) was determined in morning urine samples by the method of Sandell and Kolthoff. RESULTS: The average UIC in the whole studied group was 156,1 +/- 124,9 microg/l. Woman showed lower UIC than man (132,9 microg/l vs 177,5 microg/l). In 8% of patients iodine concentration was below 50 microg/l and in 64% of patients it was 100 microg/l or more. In the case of persons consuming limited, low amount of salt, the average urine iodine concentration was 150,3 microg/l, whereas those who add some salt to a dish was 162,4 microg/l. In hypertension patients ioduria was lower than in persons with normal blood pressure (153,1 microg/l vs 164,9 microg/l). CONCLUSIONS: The model of iodine prophylaxis has used in Poland is effective. It also concerns persons consuming limited amount of salt in the our studies group. The amount of consumed salt should be determined by measuring of Na+ concentration in 24-hour urine collection. Additional monitoring of iodine supply is necessary because of possible consumption of iodine from other sources than salt.

Adult↗
PubMed2005

[Adrenal tuberculosis as a cause of primary adrenal insufficiency--case report].

Adrenal tuberculosis is relatively infrequent cause of primary adrenocortical insufficiency in developed countries. Adrenal involvement is most often the result of hematogenous spread of the pulmonary tuberculosis. Isolated adrenal tuberculosis, especially with enlargement of adrenal glands can cause diagnostic problems and requires differentiation from primary or secondary neoplastic disease. In this paper we present a case of 61-year-old man with several months history of adrenocortical insufficiency without signs of pulmonary tuberculosis. Computed tomography scan revealed asymmetrical mass-like enlargement in adrenal glands. Despite of consecutive investigations, the diagnosis remained uncertain. Because of the possibility of neoplastic process of unknown origin, the patient was qualified for surgical exploration during which both enlarged glands were removed. The diagnosis of tuberculosis was made on microscopic examination.

Addison Disease↗
PubMed2004

[Iodine supply in school children three years after introduction of obligatory salt iodization].

Three years after introduction of obligatory salt iodization in Poland we evaluated iodine supply in children from Mazovia region. Urinary iodine concentration (UIC) was estimated in morning samples from 779 schoolchildren aged 6-14 years. Previous investigation 7 years ago revealed mild or moderate iodine deficiency in this area. UIC was lower than 100 micrograms/l in 80% of samples and mean UIC was 56.9 +/- 42.3 micrograms/l. According to WHO and ICCIDD recommendations median value of UIC at least 100 micrograms/l in the representative sample of population indicates satisfactory iodine supply. Recent data revealed that UIC was much higher than in the first phase of study, 7 years ago--mean 115.5 +/- 76.6 micrograms/l and median 100.69 micrograms/l. UIC lower than 100 micrograms/l occurred in 48% of samples, more frequently in rural regions. Iodine supply in the region was diversified--we revealed rural cohort where mean and median values of UIC (corresponding 78.96 +/- 47 micrograms/l and 67.8 micrograms/l) were unexpectedly low. Our results confirm the improvement of iodine supply in Poland after 1997. Nevertheless, taking under consideration that daily iodine supply in children and adolescents should reach 120-150 micrograms, the situation is not fully satisfactory--almost in half of schoolchildren iodine consumption hardly reaches recommended value for the whole population. We stress the necessity of continuous monitoring of the adequacy of iodine supplementation and its results.

Adolescent↗
PubMed2004

[Diagnostic difficulties in Grave's orbitopathy--case report].

Graves' orbitopathy is caused by intraorbital inflammatory reaction due to autoimmune thyroid disease. In most cases the diagnosis is based on the coexistence of typical eye signs and hyperthyroidism symptoms. In presented case, the absence of thyroid dysfunction implicated performance of differential diagnosis. Among many available diagnostic tools nuclear magnetic resonance seems to be the most accurate in confirmation of diagnosis of Graves' orbitopathy.

Aged↗
PubMed2002

Salt iodination as a effective method of iodine supplementation.

BACKGROUND: In January 1997 a new approach to preventing iodine deficiency was introduced in Poland. The goal of the present study was to determine whether the mandatory iodization of kitchen salt (30 mg KI/kg) has had any impact on ioduria. MATERIAL/METHODS: The study was performed on 29 healthy volunteers, aged 22-29 (average age 23.93 +/- 1.14), examined in 1996 and retested after 36 months of iodine supplementation in 1999. Each person underwent a physical examination and thyroid ultrasonography. The iodine level was determined using morning urine samples. RESULTS: For the duration of the study thyroid volume remained unchanged, ranging from 11.48 I3.89 ml in 1996 to 12.11 +/- 3.85 ml in 1998. The echostructure was normal in all subjects both in 1996 and in 1999. In 1996 the iodine concentration in urine (ICU) in the study group averaged 100.4 +/- 41.5 mg/L (range from 43.3 to 175.6 microg/L). Seventeen persons had an iodine concentration below 100 microg/L. In 1999 the average ICU was 140.7 +/- 78.87 microg/L. Three subjects had a lower ICU in 1999 (53.93 +/- 24.65 microg/L) than in 1996 (104.1 +/- 24.6 microg/L). These persons claimed to have completely eliminated the use of added salt in their diet. CONCLUSIONS: We conclude that mandatory iodine supplementation method is sufficiently effective when salt is used in the diet. In the case of restrictions on salt consumption the use of preparations containing iodine should be recommended.

Adult↗
PubMed2002

[Diagnosis and treatment of thyroid nodules].

The paper presents current diagnostic and therapeutic approach of thyroid nodules. TSH and iodine are the main goitrogenic agents, but there are also other auto- para-endocrinal factors that play very important roles in goiter growth as well as in the intrinsic growth potential of some thyroid follicular cells. The diagnosis of thyroid nodule demands further investigation such as thyroid function evaluation and distinction between benign from malignant nodules using FNAB. The confirmation or suspicion of malignancy or presence of compressive symptoms is indication for surgery. In benign lesions, without features of hyperthyroidism observation may be advised. Thyroxine therapy may be proposed to some patients but the possibility of side-effects should always be taken into account, as well as the low efficacy of this treatment.

Goiter, Nodular↗