Biomedical subjects

Walton Nosé

Publications and source records attributed to Walton Nosé.

9 recordsLinked to original sources

PubMed2006

[MALKS: specifications and development].

PURPOSE: To describe the characteristics of a new artificial anterior chamber (MALKS, Loktal, São Paulo, Brazil). METHODS: Characteristics analysis and description of a new artificial anterior chamber MALKS (Micro automated lamellar keratoplasty system). RESULTS: MALKS is composed of eight parts: a) artificial chamber; b) cornea's fix ring; c) nut to join the cornea's fix ring; d) rail and adjuster of lamellar diameter; e) flatteners, to pre-determine lamellar diameter; f) infusion system, that allows the digital objective peroperative control of the intracameral pressure; g) automated microkeratome, and h) marker. CONCLUSION: MALKS uses the same automated microkeratome developed for LASIK, can allow corneal lamella obtention with predetermined thickness and diameter, as well as the digital objective peroperative control of the intracameral pressure. This new artificial anterior chamber can be an important tool for superficial and endothelial keratoplasty.

Anterior Chamber↗

PubMed2006

[Evaluation of the cut quality of the Masyk microkeratome in obtaining corneal flap from porcine eyes].

PURPOSE: Evaluation of the cut quality of the Masyk microkeratome in obtaining corneal flap from porcine eyes. METHODS: Prospective study with 31 porcine eyes divided into two groups: 15 eyes with programmed flap thickness of 160 microm and 9.5 mm diameter (Group 1), and 16 eyes with programmed flap thickness of 140 microm and 8.5 mm diameter (Group 2). Corneal thickness was calculated with a P55 pachymeter (Paradigm, USA) and the diameter with compass. RESULTS: No complications were observed during the use of the microkeratome. In group 1, the central corneal thickness mean was 146.33 +/- 15.43 microm, range between 127 and 186 microm, and the vertical diameter mean was 9.39 +/- 0.26 mm, range from 8.90 to 9.85 mm. In group 2, the central corneal thickness mean was 128.75 +/- 18.83 microm, range from 71 to 178 microm, and the vertical diameter mean was 8.27 +/- 0.20 mm, range from 7.95 to 8.65 mm. CONCLUSION: The Masyk microkeratome showed to be effective and safe to produce corneal flaps with appropriate thickness and diameter in porcine eyes.

Animals↗

PubMed2006

Wavefront analysis and contrast sensitivity of aspheric and spherical intraocular lenses: a randomized prospective study.

PURPOSE: To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration, and other terms), and contrast sensitivity in 120 eyes implanted with one monofocal aspheric intraocular lens (IOL) and two spherical IOLs. DESIGN: Randomized prospective study. METHODS: Sixty patients were randomized to receive three IOL types: Alcon AcrySofIQ (40 eyes), AcrySofNatural (40 eyes), and advanced medical optic (AMO)Sensar (40 eyes). Complete ophthalmologic examination including uncorrected visual acuity (UCVA), best-spectacle corrected visual acuity (BSCVA), corneal topography, and wavefront analysis were performed preoperatively, 30 days, and 90 days postoperatively. Pelli-Robson chart test and functional acuity contrast testing (FACT-Optec6500) were performed approximately 50 days after surgery. Statistical analyses were performed using analysis chi(2), analysis of variance (ANOVA), and multiple comparisons Tukey test. RESULTS: After 90 days, all eyes had postoperative BSCVA > or =20/32. The AcrySofIQ IOL showed statistically significant less induction of spherical aberration (P < .001) when compared with the AMOSensar and the AcrySofNatural IOLs. The AMOSensar presented significantly less spherical aberration then the AcrySofNatural (P < .05). The AcrySofIQ also had lower values of total and high-order aberration (HOA) (P < .05) when compared with the AMOSensar and the AcrySofNatural. The mean values of trefoil 9, coma, and HOA root mean square (RMS) decreased between one and three months (P < .001, P < .001, P = .023, P < .001, respectively) in all groups. Mean Pelli-Robson contrast sensitivity values in photopic condition were similar between the groups. The AcrySofIQ showed better results in 3cpd spatial frequency in mesopic condition using FACT-Optec 6500 (P = .008), although there were no statistical differences in photopic and mesopic with glare conditions.

Aged↗

PubMed2006

Diagnosis of epithelial ingrowth after penetrating keratoplasty with confocal microscopy.

PURPOSE: To report confocal microscopy use in the clinical diagnosis of epithelial ingrowth after penetrating keratoplasty (PKP). METHODS: A 36-year-old female patient with keratoconus developed a well-delimited posterior hazy membrane covering the inferior two thirds of the cornea 3 months after an uneventful PKP. A posterior corneal line was present resembling an endothelial graft rejection line, but with no keratic precipitates or corneal edema. Ocular hypertension was not observed. Confocal microscopy was performed to elucidate the diagnosis. RESULTS: Confocal microscopy showed epithelium and stroma with normal findings. Two distinct cellular types were presented at the endothelium layer. Enlarged endothelial cells were observed in the superior part of the cornea up to the leading edge of the hazy membrane. In the middle and inferior part of the graft, the cells were larger, with polygonal shape and easily recognizable hyperreflective nuclei, suggestive of epithelial cells. With these confocal microscopy findings, the patient was promptly submitted to another PKP. Histologic analysis confirmed the diagnosis of epithelial ingrowth. CONCLUSION: Confocal microscopy imaging technique seems to be a useful tool in the early diagnosis of epithelial ingrowth after PKP.

Adult↗

PubMed2003

Ultrasound biomicroscopy and Scheimpflug photography of angle-supported phakic intraocular lens for high myopia.

PURPOSE: To evaluate the equivalence of Scheimpflug photography (SP) and ultrasound biomicroscopy (UBM) in determining corneal epithelium-intraocular lens (IOL) and border IOL-iris distances. SETTING: Universität Erlangen-Nuremberg, Erlangen, Germany. METHODS: In 26 eyes of 17 patients who had a NuVita MA20 angle-supported anterior chamber intraocular lens (Chiron-Domilens), SP and UBM were used to evaluate the distance between the endothelium and the anterior IOL face in central and peripheral regions (12 o'clock and 6 o'clock positions) and between the border of the anterior IOL face and the iris. The Wilcoxon test was used for statistical analysis. RESULTS: The mean central endothelium-anterior IOL face distance was 2.01 mm and 2.00 mm by SP and UBM, respectively. The mean peripheral endothelium-anterior IOL border distance was 1.28 mm and 1.58 mm, respectively, and the mean peripheral anterior IOL face-iris distance, 0.89 mm and 0.75 mm, respectively. CONCLUSIONS: The difference between the 2 methods in the central endothelium-anterior IOL face distance was not significant (methods were equivalent), but the difference in the peripheral endothelium-anterior IOL face distance was. This may be the result of difficulty in obtaining the exact transition point between the IOL and the haptics by SP examination. The difference between the 2 methods in the IOL border-iris distance was also significant because of the irregularity of the iris surface; therefore, measurements were performed at different sites along this structure. The significant differences in the peripheral endothelium-IOL and IOL border-iris distances indicate that although both methods are useful, they are not equivalent.

Adult↗

PubMed2002

Hyperopic laser-assisted in situ keratomileusis for radial keratotomy induced hyperopia.

PURPOSE: To evaluate hyperopic laser in situ keratomileusis (H-LASIK) for radial keratotomy (RK)-induced hyperopia. DESIGN: Noncomparative interventional retrospective nonconsecutive case series. PARTICIPANTS: Sixty-nine eyes of 47 patients who had undergone RK and were seen with induced hyperopia. METHODS: H-LASIK was performed with an excimer laser. MAIN OUTCOME MEASURES: The mean refractive error, in spherical equivalents (SE), uncorrected visual acuity (UCVA), and best spectacle-corrected visual acuity (BSCVA) before and after H-LASIK are reported. Safety was analyzed using a mean follow-up time of 6.6 plus minus 3.24 months. RESULTS: Preoperative mean SE was +3.4 plus minus 1.6 diopters (D). Postoperative mean SE was -0.32 plus minus 1.2 D. A high percentage of eyes (79.7%; n = 55) were between plus minus1.0 D of emmetropia and 88% within plus minus 2.0 D. Preoperative BSCVA was 20/20 in 53.6% of eyes (n = 37) and 20/40 or better in 100% (n = 69). Postoperative BSCVA was 20/20 in 55% of eyes (n = 38) and 20/40 or better in 95.6% (n = 66) of eyes. Preoperative UCVA was less-than-or-equal20/50 in 52 cases (75.4%). Postoperative UCVA was 20/20 in 13 cases (18.8%) and greater-than-or-equal20/40 in 45 cases (65.2%). Four eyes lost 2 Snellen lines because of epithelial ingrowth in the interface (n = 3) and diffuse lamellar keratitis (Sands of the Sahara syndrome; n = 2). One of the eyes with Sahara syndrome also had epithelial ingrowth and flap necrosis. Thirteen eyes lost 1 Snellen line, and 50 eyes maintained or gained Snellen lines. The only intraoperative complication was incision opening (n = 8) while the flap was lifted; there were no further complications. These patients did not lose any Snellen lines of their BSCVA. CONCLUSIONS: H-LASIK can be used successfully to correct RK-induced hyperopia.

Adult↗

PubMedDate not supplied

[In vivo confocal microscopy in the diagnosis of fungal keratitis: case report].

The authors describe a case of fungal keratitis that the in vivo confocal microscopy helped in the diagnosis and follow-up. Confocal microscopy was done in a patient's ulcer that did not improve with several topical medicines. Corneal scrapings were obtained and culture results were without conclusion. We observed hyphae and infectious collections on confocal microscopy. New corneal culture showed Fusarium sp ten days after confocal diagnosis.

Eye Infections, Fungal↗

PubMedDate not supplied

[Endothelial damage after planned extracapsular cataract extraction and phacoemulsification of hard cataracts].

PURPOSE: To evaluate and compare the endothelial damage after planned extracapsular cataract extraction (ECCE) and phacoemulsification of very hard cataracts. METHODS: In this prospective, randomized study, 41 patients with age-related and very hard cataract were divided into two groups: in group 1 (21 patients) an extracapsular cataract extraction was performed and in group 2 (20 patients), phacoemulsification. In both groups, intraocular lenses were implanted in the capsular bag. Preoperatively and 1, 3 and 6 months postoperatively, a complete ophthalmological examination, endothelial specular microscopy, and ultrasonic pachymetry were done. Endothelial cell loss, pleomorphism, polymegathism and corneal thickness were studied. RESULTS: Both groups presented an endothelial cell loss in the postoperative time, as compared with the preoperative values, but there were no significant differences among the postoperative values (1, 3 and 6 months). Six months after surgery, mean cell loss was 28.50% in group 1 and 34.77% in group 2. There were no differences among the indexes of pachymetry, polymegathism and pleomorphism between the two groups. CONCLUSIONS: Endothelial response was not statistically different between the two studied groups.

Aged↗

PubMedDate not supplied

[Evaluation of the cut quality of Masyk microkeratome in obtaining corneal flap from human eyes of an eye bank].

PURPOSE: To evaluate the cut quality of Masyk microkeratome in obtaining a corneal flap from human eyes of Eye Banks. METHODS: Prospective study with 20 human eyes from Eye Banks. All flaps were programmed to obtain 160 microm thickness and 9.5 mm diameter. The thicknesses were calculated with P55 pachymeter (Paradigm, USA), and diameter with compass. RESULTS: No complications were observed during the use of the microkeratome. The central corneal thickness average was 160.34+/-5.10 microm and range from 149 to 181 microm. The vertical diameter average was 9.64+/-0.16 mm and range from 9.30 to 9.85 mm. CONCLUSION: Masyk microkeratome showed to be effective for obtention of corneal flap with appropriate thickness and diameter from human corneas of Eye Banks.

Corneal Stroma↗