Biomedical subjects

W van Delft

Publications and source records attributed to W van Delft.

4 recordsLinked to original sources

PubMed1990

[Lead poisoning in cattle in north Netherlands. October 1989-January 1990].

By the end of 1989 a serious lead intoxication of cattle occurred in the northern part of the Netherlands (provinces Groningen and Friesland). This intoxication appeared to be caused by contaminated feed. Over 300 farms were stricken, with about 15,500 animals (mostly dairy cattle). In a period of one to four weeks these animals consumed about 1,000 kg of lead. This resulted in lead levels in milk, livers, and kidneys above the regulatory safety limits. Thanks to the chelating therapy that was rapidly applied by the local veterinarians, only about 30 animals died of an acute lead intoxication. The cooperating governmental and private authorities took action to prevent exposure of consumers to lead-contaminated animal products. Based on careful estimations, predictions were made of the lead levels to be expected in animals products and the time needed for depletion of these levels. The appropriate animals were marked to ensure their identification, and the decline in time of the lead levels in milk and offals was conscientiously monitored. In the second week of 1990 the lead concentrations were decreased to levels well below the regulatory limits, and hence the marks were removed from the animals.

Animal Feed↗

PubMed1988

Arsenic, cadmium, lead and mercury in meat, livers and kidneys of sheep slaughtered in The Netherlands.

The results obtained between 1981 and 1986 in a Dutch monitoring programme investigating the presence of arsenic, cadmium, lead and mercury in meat, livers and kidneys of sheep are presented. For the meat, livers and kidneys, the median values were 0.001, 0.003, and 0.007 mg/kg (fresh weight) for arsenic; 0.003, 0.054, and 0.098 mg/kg for cadmium; 0.04, 0.85, and 0.36 mg/kg for lead; and 0.001, 0.002, and 0.007 mg/kg for mercury. During the reported period, no clear trends were observed. The results are compared with the data from other countries. The mercury and arsenic concentrations in meat and organs may be regarded as low, but the levels of lead in livers are relatively high. The lead concentrations in livers showed seasonal fluctuations, the highest concentrations usually being found during the winter. Significant linear relationships were found between the concentrations in livers and kidneys for arsenic, cadmium and mercury. Tissue trace element levels were not related to the age of the investigated animals.

Animals↗

PubMed1986

Arsenic, cadmium, lead and mercury in meat, livers, and kidneys of swine slaughtered in The Netherlands during the period 1980-1985.

The results obtained between 1980 and 1985 in a Dutch monitoring programme on the presence of arsenic, cadmium, lead and mercury in meat and organs of swine are presented. For meat, livers and kidneys the median values were, respectively, 0.001, 0.001, and 0.003 mg/kg (fresh weight) for arsenic, 0.002, 0.044, and 0.260 mg/kg for cadmium, 0.01, 0.03, and 0.08 mg/kg for lead and 0.001, 0.002, and 0.005 mg/kg for mercury. No significant changes were observed in the tissue arsenic and mercury levels during the investigated period. A decrease was observed in the cadmium and lead concentrations in livers and kidneys. The provisional Dutch legal limits were exceeded only for lead in one kidney sample. A significant recti linear relation was found between the cadmium concentrations in livers and kidneys. In general the cadmium and lead levels found are comparable with published data, reported from other countries. Compared with data from the literature, the arsenic and mercury concentrations found in the present study are low.

Animals↗

PubMedDate not supplied

Lead intoxication in cattle: a case report.

During the autumn of 1989 a feed contamination induced a widespread lead intoxication of cattle in the northern provinces of The Netherlands (Groningen and Friesland). Over 300 farms were involved, affecting about 15,500 animals (mostly dairy cattle). For a period of one to four weeks these animals took up a thousand kg of lead. This resulted in lead levels in milk, livers, and kidneys above the regulatory safety limits. Due to the chelating therapy, which was rapidly applied by the local veterinarians, only about 30 animals died of an acute lead intoxication. A joint action of the governmental and private authorities prevented exposure of consumers to lead-contaminated animal products. Based on observations, measurements and literature data, predictions were made of the lead levels to be expected in animal products and the time needed for depletion of these levels. The appropriate animals were ear-tagged to ensure their identification, and the decline in time of the lead levels in milk and offals was conscientiously monitored. In the second week of 1990 the lead concentrations were decreased to levels well below the regulatory limits, and hence the tags were removed. The present paper reports our observations and conclusions, especially regarding treatment, predictions and outcome of this incident.

Animal Feed↗