Biomedical subjects

W de Decker

Publications and source records attributed to W de Decker.

At least 55 records · Page 3Linked to original sources

PubMed1975

[Investigations on the effectiveness of a new antimycotic through experimental keratomycosis in rabbits (author's transl)].

Thirty-two rabbits infected with Fumigatus keratitis were treated for a period of 10 to 20 days with a new antifungal agent known as "BAY b 5097" (Canesten). It was administered to 6 animals (500 mg/kg body weight; 12 eyes) orally; 20 received unilateral topical treatment. In both groups the therapy failed to supress mycosis in the avascular cornea. In topical treatment problems concerning common solvents arise: They are unable to reach the intracorneal infection, and most of them are incompatible for conjunctival use.

Administration, Oral↗

PubMed1975

[Standard candida mycosis in the rabbit eye (author's transl)].

Whole-body X-irradiation administered to rabbits prior to intracorneal inoculation with Candida albicans is required to produce a verifiable mycotic keratitis. Damage to the corneal tissue, which in rabbits is generally resistant to Candida, can thus be avoided. The mycosis usually lasts for a period of 12 to 14 days. Twenty-four animals (48 eyes) were infected. The fungi were recultivated in 21 animals (24 eyes). All attempts were successful.

Animals↗

PubMed1975

[Artificial divergence in treatment of anomalous correspondence (author's transl)].

Artificial divergence causes a change of correspondence in about 60% of cases of alternating comitant convergent strabismus. This means a merely formal normalisation, since only one third of the cases can be cured to a level of +/-1degree of arc related to the true position of the eyes. These cases do not show any scotoma under campimetry on the phase difference haploscop (Aulhorn). An other third achieved a status with a tolerance of +/- 2 degrees and microscotomata. The last third did not show a normalisation, mostly due to a preexisting angle smaller than 5 degrees of arc. The number of full cures was limited, since the onset of squint was early in the majority of cases. One half of the 271 cases were treated by surgical overcorrection and following reoperation. The other half by small initial surgery, prismatic overcorrection followed by prismatic compensation and small second operation.

Humans↗

PubMed1975

[Cüppers' "Fadenoperation" for complicated eye-muscle disturbances and non-accomodative convergence-excess (author's transl)].

More than ever the "Fadenoperation" according to Cüppers has become an important method to improve the pathological relation between eye position, innervation, and resulting motility. This is achieved by sutural fixation of an over-acting muscle far behind its original insertion. In particular a palsy can be influenced by making a handicap for the contralateral yoke muscle. 40 patients (palsies, nystagmus, strabismus incomitans), who have been treated so far, may demonstrate how the purpose of changing the innervation rather than the length of muscles can be integrated in general therapeutic schemes. The procedure is also helpful in weakening the over-acting int. rectus muscle in strabismus cases with habitual excessive convergence.

Accommodation, Ocular↗

PubMed1975

[Classification of nonparetic vertical strabismus related to vertical rectus surgery (author's transl)].

Results following vertical rectus muscle recession and classification of vertical strabismus due to the field of action of the vertical recti. 100 cases of vertical squint underwent surgery of the vertical recti (recession of the superior rectus muscle in 92 cases). One third achieved binocular functions partly based upon microtropia. It may be of special interest that 5 of 19 patients with "dissociated" alternating deviations could be cured by bilateral recession of the superior rectus. The authors try to give their own modification of the difficult classification of the different clinical types of vertical squint, since the results following the treatment of the various types were quite different.

Child↗

PubMed1975