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Biomedical subjects

W Yamamoto

Publications and source records attributed to W Yamamoto.

61 records · Page 4Linked to original sources
PubMed1977

Contrast nasopharyngography.

Contrast nasopharyngography was performed in 25 cases of nasopharyngeal lesions, 15 of which were carcinoma, six malignant lymphoma, and four benign lesions including neurofibroma, haemangioma, angiofibroma and tuberculosis. Nasopharyngography was also performed in 22 cases with extranasopharyngeal lesions, including nine of head and neck malignant lymphoma and 13 of tumours originating in adjacent organs. To describe the extent and site of the tumour, the nasopharyngeal walls were labelled segment 1 to 15 on axial and lateral views. The lateral skull films were negative in five of eight small malignancies involving no more than five wall segments, and also negative in six of 10 cases of unilateral involvement. Small lesions involving the unilateral fossa of Rosenmueller and/or the superolateral wall were frequently undetected. Nasopharyngography is indicated in cases where clinical suspicions of a lesion remain after a normal straight film. When malignancies were treated with radiation therapy a pre-irradiation nasopharyngogram clearly depicted the site and extent of the disease, and a post-irradiation study showed a marked shrinkage of the tumour mass and/or markedly improved raggedness of the wall of the nasopharynx. Four benign lesions showed large space-occupying lesions. In the case of tuberculosis, for example, the nasopharyngeal cavity was totally obliterated by the granulomatous tissue. In nine cases of malignant lymphoma involving the neck nodes or the palatine tonsil, the nasopharyngogram was normal.

Contrast Media↗
PubMedDate not supplied

Management of unruptured intracranial aneurysm in Japan: a Markovian decision analysis with utility measurements based on the Glasgow Outcome Scale.

The purpose of this study was to analyze the management of individual patients with unruptured intracranial aneurysms (UN-ANs) using a decision-analytic approach. Transition probabilities among Glasgow Outcome Scale (GOS) categories were estimated from the published literature and data from patients who had been treated at Kitasato University Hospital. Utilities were obtained from 140 health providers based principally on the GOS. Baseline analysis for a healthy 40-year-old man with an anterior UN-AN less than 10 mm in diameter showed that the quality-adjusted life expectancies for preventive operation and follow-up were 15.34 and 14.66 years, respectively. For a follow-up strategy to be preferred, the annual rupture rate had to be as low as 0.9%. These results were sustained through extensive sensitivity analysis. The results support preventive operation for UN-ANs, and identify problems that can be clarified with a well-designed stratified clinical trial.

Adult↗