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Biomedical subjects

W Wertelecki

Publications and source records attributed to W Wertelecki.

At least 55 records · Page 3Linked to original sources
PubMed1986

Diet, blood pressure, and hematologic variables of nulliparous women attending a prenatal clinic.

Diet, hematology, and blood pressures of 1800 black and white nulliparous women were surveyed at a prenatal clinic. Although black women had higher blood pressure and lower hemoglobin and hematocrit means that white women, no racial differences were found for prevalence of anemia or hypertension. White women reported less adequate intakes of protein/iron and vitamins B and C compared with black women. No associations between dietary intake and anemia or hypertension were found in univariate analysis. Failure to find racial differences in prevalence of hypertension and anemia may reflect improvements in the dietary supplementation and health care available to lower socioeconomic, black women in the last decade.

Adolescent↗
PubMed1986

Trend associations of smoking with maternal, fetal, and neonatal morbidity.

Smoking habits, prenatal health, and pregnancy outcome were surveyed among 1700 nulliparous women. During pregnancy, increases in levels of hemoglobin and hematocrit and the frequency of women reporting bleeding and decreases in diastolic pressure and frequency of toxemia were observed with increased maternal smoking. A higher frequency of fetal bradycardia was detected among women smoking greater than or equal to one-half pack per day. With increased smoking there was an increased frequency of abnormal placentas. Mean birth weight and crown-heel length decreased with increased smoking, and neonates born to women smoking greater than or equal to one-half pack per day had a higher frequency of jaundice. The association between smoking and reduced birth weight and crown-heel length persisted after controlling for gestational age, maternal weight gain, prenatal visits, and other confounding variables.

Birth Weight↗
PubMed1985

Earlier maturation of pregnant black and white adolescents.

A survey was made of the menarcheal age and anthropometry of 1,844 lower income, nulliparous female patients receiving prenatal care. No differences were observed between black and white patients in height and maximum pregnant weight. A significantly earlier mean menarcheal age was observed in adolescents (12 to 16 years) compared with adults (17 to 31 years). Younger adolescents (12 to 14 years) of both races were taller and heavier (prepregnancy) than National Center for Health Statistics standards and had a significantly greater weight-for-height. Menarcheal age and body habitus were consistent with other reports that younger pregnant adolescents tend to be earlier maturers than older pregnant adolescents and adults. Compared with their age-group cohorts (13 to 31 years) in the two-decades-old Collaborative Perinatal Study of the National Institute of Neurological Communicative Disorders and Stroke, these female patients were larger and had greater pregnancy weight gains. These anthropometric findings may reflect the two decades of improvements in social assistance and prenatal care for lower income women.

Adolescent↗
PubMed1985

Similarity of effects--experimental hyperthermia as a teratogen and maternal febrile illness associated with oromandibular and limb defects.

Experimental hyperthermia in pregnancy causes oromandibular and limb anomalies. In humans, hyperthermia has been suspected of being teratogenic. Two patients were investigated; both had limb defects and one had oromandibular anomalies. Their mothers had a febrile illness at about the 10th wk of gestation. The similarity of defects produced by experimental hyperthermia and those reported here is striking.

Abnormalities, Multiple↗
PubMed1985

Non-neural malignancy complicating neurofibromatosis in two relatives.

In a family with neurofibromatosis, an affected 16-year-old male developed undifferentiated lymphoma that evolved into acute lymphocytic leukemia. Five years later, his 7-month-old nephew with neurofibromatosis developed a prostatic embryonal rhabdomyosarcoma. This illustrates familial neurofibromatosis complicated by non-neural malignancy in relatives.

Adolescent↗
PubMed1985

Maternal sociomedical characteristics and birth weights of firstborns.

Pregnancy outcome and sociomedical characteristics were examined in a sample of 1844 black and white primiparous females who received prenatal care. White females were more frequently married and more likely to live with their husbands than with their parents. Black females were better educated and more interested in obtaining further education. White women smoked significantly more cigarettes. There were no differences in contraceptive use in black and white females. Number of prenatal visits was least frequent among adolescent black females. With the exception of a higher incidence of vaginal infection among black females, there were no significant differences in general health status. There were no differences in birth weights between the firstborns of black and white adolescents, but adult white females had significantly heavier firstborns than blacks. Nonetheless, no differences were found in prevalence of low birth weight-for-gestational neonates between black and white females. Infrequent prenatal visits, maternal diabetes and smoking were the only significant multivariate factors associated with the occurrence of a low birth weight-for-gestational age neonate among the total sample.

Adolescent↗
PubMed1985

Abnormal centromere-chromatid apposition (ACCA) and Peters' anomaly.

Abnormal centromere-chromatid apposition (ACCA) was noted in a patient with Peters' anomaly. Previous reports of ACCA emphasized its association with tetraphocomelia and other congenital malformations (Roberts, SC Phocomelia, Pseudothalidomide Syndromes). This report expands the array of congenital malformations associated with ACCA and emphasizes the diagnostic importance of ocular defects for the ascertainment of additional cases of ACCA and its possible relationship with abnormal cell division.

Centromere↗
PubMed1982

Evidence that sister chromatid exchanges and chromatid breaks are two independent events.

The relative frequencies of sister chromatid exchanges (SCE) and chromatid breaks in BrdU (5-bromodeoxyuridine) - sensitive site (lq22 leads to lq23) in Chinese hamster cells after BrdU incorporation were studied. The results show that chromatid breaks do not follow the "exchange hypothesis" and provide evidence that chromatid breaks and SCEs are two independent events despite some common features.

Animals↗
PubMed1981

Utilization of prenatal genetic diagnosis in women 35 years of age and older in the United States, 1977 to 1978.

As a measure of access to and acceptability of prenatal chromosomal diagnosis among older gravidas, we determined the ratio of use of prenatal diagnosis among women 35 years of age and older in Alabama, California, Manhattan, and Nebraska for the period 1977-1978. Utilization ratios were higher in 1978. Overall, utilization ratios were between 6% and 28%, well below the adjusted rates of 40% to 50% found in certain United States and British localities. Urban women tended to have higher utilization ratios than had rural women, and white women had higher ratios than had black women. Ratios were extremely low for black and rural residents. The oldest women (those greater than or equal to 40 years), who were at fivefold greater risk than women 35 to 36 years of age, had less than a onefold increase in utilization over the latter groups. The vast majority of older gravidas initiated prenatal care sufficiently early in their pregnancies to receive prenatal diagnosis. Current program strategies need to ensure access to prenatal diagnosis, especially for women greater than or equal to 40 years of age, women who are black, and women who live in rural areas.

Adult↗