Biomedical subjects

W Wegscheider

Publications and source records attributed to W Wegscheider.

At least 19 recordsLinked to original sources

PubMed2003

An uncertainty budget for trace analysis by isotope-dilution ICP-MS with proper consideration of correlation.

Isotope-dilution mass spectrometry (IDMS) is considered to be a method without significant correction factors. It is also believed that this method is well understood. But unfortunately a large number of different uncertainty budgets have been published that consider different correction factors. These differences lead to conflicting combined uncertainties especially in trace analysis. It is described how the known correction factors must be considered in the uncertainty budget of values determined by IDMS combined with ICP-MS (ICP-IDMS). The corrections applied are dead time, background, interference, mass discrimination, blank correction and air buoyancy.IDMS measurements consist always of a series of isotope abundance ratio measurements and can be done according to different measurement protocols. Because the measurement protocols of IDMS are often rather sophisticated, correlations of influence quantities are difficult to identify. Therefore the measurement protocol has to be carefully considered in the specification of the measurand and a strategy is presented to properly account for these correlations. This will be exemplified for the estimation of mass fractions of platinum group elements (PGEs) and Re in the geological reference material UB-N (from CRPG-CNRS, Nancy in France) with ICP-IDMS. The PGEs with more than one isotope and the element Re are measured with on-line cation-exchange chromatography coupled to a quadrupole ICP-MS. All contents are below 10 microg kg(-1). Only osmium is separated from the matrix by direct sparging of OsO(4) into the plasma. This leads to transient signals for all PGEs and Re. It is possible to estimate the combined uncertainties and keep them favourably small despite the low contents, the transient signals and the sophisticated correction model.

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PubMed2003

Kondo effect in a few-electron quantum ring.

A small quantum ring with less than ten electrons was studied by transport spectroscopy. For strong coupling to the leads a Kondo effect is observed and used to characterize the spin structure of the system in a wide range of magnetic fields. At small magnetic fields Aharonov-Bohm oscillations influenced by Coulomb interaction appear. They exhibit phase jumps by pi at the Coulomb-blockade resonances. Inside Coulomb-blockade valleys the Aharonov-Bohm oscillations can also be studied due to the finite conductance caused by the Kondo effect. Astonishingly, the maxima of the oscillations show linear shifts with increasing magnetic field and gate voltage.

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PubMed2003

Observation of retardation effects in the spectrum of two-dimensional plasmons.

Retardation effects, theoretically predicted more than 35 years ago, are observed in the spectrum of two-dimensional plasmons in high-electron-mobility GaAs/AlGaAs quantum wells. In zero magnetic field, a strong reduction of the resonant plasma frequency is observed due to the hybridization of the plasma and light modes. In a perpendicular magnetic field B, hybrid cyclotron-plasmon modes appear with a very unusual dependence of the frequency on B field. Experimental results are in excellent agreement with the theory.

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PubMed2002

From quantum Hall ferromagnetism to huge longitudinal resistance at the 2/3 fractional quantum Hall state.

We observe the transition from a spin-unpolarized to a polarized nu=2/3 fractional quantum Hall state at low currents (<5 nA), recently described in terms of quantum Hall ferromagnetism, versus density and parallel magnetic field. At larger currents the time and current dependent huge longitudinal resistance (HLR) is always initiated at the transition. Transport in the HLR regime is linear and the amount of current-induced nuclear polarization in the HLR is comparable to the thermal nuclear polarization at approximately 20 mK and 10 T. A current-induced disorder in the nuclear polarization is speculated to cause the enhanced resistance in the HLR regime.

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PubMed2002

Spin-galvanic effect.

There is much recent interest in exploiting the spin of conduction electrons in semiconductor heterostructures together with their charge to realize new device concepts. Electrical currents are usually generated by electric or magnetic fields, or by gradients of, for example, carrier concentration or temperature. The electron spin in a spin-polarized electron gas can, in principle, also drive an electrical current, even at room temperature, if some general symmetry requirements are met. Here we demonstrate such a 'spin-galvanic' effect in semiconductor heterostructures, induced by a non-equilibrium, but uniform population of electron spins. The microscopic origin for this effect is that the two electronic sub-bands for spin-up and spin-down electrons are shifted in momentum space and, although the electron distribution in each sub-band is symmetric, there is an inherent asymmetry in the spin-flip scattering events between the two sub-bands. The resulting current flow has been detected by applying a magnetic field to rotate an optically oriented non-equilibrium spin polarization in the direction of the sample plane. In contrast to previous experiments, where spin-polarized currents were driven by electric fields in semiconductor, we have here the complementary situation where electron spins drive a current without the need of an external electric field.

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PubMed2002

Cyclotron resonance of composite fermions.

It is occasionally possible to interpret strongly interacting many-body systems within a single-particle framework by introducing suitable fictitious entities, or 'quasi-particles'. A notable recent example of the successful application of such an approach is for a two-dimensional electron system that is exposed to a strong perpendicular magnetic field. The conduction properties of the system are governed by electron-electron interactions, which cause the fractional quantum Hall effect. Composite fermions, electrons that are dressed with magnetic flux quanta pointing opposite to the applied magnetic field, were identified as apposite quasi-particles that simplify our understanding of the fractional quantum Hall effect. They precess, like electrons, along circular cyclotron orbits, but with a diameter determined by a reduced effective magnetic field. The frequency of their cyclotron motion has hitherto remained enigmatic, as the effective mass is no longer related to the band mass of the original electrons and is entirely generated from electron-electron interactions. Here we demonstrate enhanced absorption of a microwave field in the composite fermion regime, and interpret it as a resonance with the frequency of their circular motion. From this inferred cyclotron resonance, we derive a composite fermion effective mass that varies from 0.7 to 1.2 times that of the electron mass in vacuum as their density is tuned from 0.6 x 10(11) cm(-2) to 1.2 x 10(11) cm(-2).

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PubMed2002

Gate-voltage control of spin interactions between electrons and nuclei in a semiconductor.

Semiconductors are ubiquitous in device electronics, because their charge distributions can be conveniently manipulated with voltages to perform logic operations. Achieving a similar level of control over the spin degrees of freedom, either from electrons or nuclei, could provide intriguing prospects for both information processing and the study of fundamental solid-state physics issues. Here we report procedures that carry out the controlled transfer of spin angular momentum between electrons-confined to two dimensions and subjected to a perpendicular magnetic field-and the nuclei of the host semiconductor, using gate voltages only. We show that the spin transfer rate can be enhanced near a ferromagnetic ground state of the electron system, and that the induced nuclear spin polarization can be subsequently stored and 'read out'. These techniques can also be combined into a spectroscopic tool to detect the low-energy collective excitations in the electron system that promote the spin transfer. The existence of such excitations is contingent on appropriate electron-electron correlations, and these can be tuned by changing, for example, the electron density via a gate voltage.

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PubMed2002

Spin-sensitive bleaching and monopolar spin orientation in quantum wells.

Spin-sensitive bleaching of the absorption of far-infrared radiation has been observed in p-type GaAs/AlGaAs quantum well structures. The absorption of circularly polarized radiation saturates at lower intensities than that of linearly polarized light due to monopolar spin orientation in the first heavy-hole subband. Spin relaxation times of holes in p-type material in the range of tens of ps were derived from the intensity dependence of the absorption.

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PubMed2002

Nonlinear charge spreading visualized in voltage-controlled lateral superlattices.

Voltage-controlled lateral potential superlattices are used to dramatically increase the lifetime of photogenerated carriers in a quantum well. These long lifetimes, together with the ability to deliberately trigger radiative recombination, enable us to directly visualize the spreading character of nonlinear Maxwell relaxation of 2D charges along narrow channels. Our system allows for temporal and spatial resolution of Maxwell kinetics, usually a very fast process and difficult to observe. The observed spreading dynamics of a 2D hole plasma is in perfect agreement with our nonlinear model.

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PubMed2001

Energy spectra of quantum rings.

Quantum mechanical experiments in ring geometries have long fascinated physicists. Open rings connected to leads, for example, allow the observation of the Aharonov-Bohm effect, one of the best examples of quantum mechanical phase coherence. The phase coherence of electrons travelling through a quantum dot embedded in one arm of an open ring has also been demonstrated. The energy spectra of closed rings have only recently been studied by optical spectroscopy. The prediction that they allow persistent current has been explored in various experiments. Here we report magnetotransport experiments on closed rings in the Coulomb blockade regime. Our experiments show that a microscopic understanding of energy levels, so far limited to few-electron quantum dots, can be extended to a many-electron system. A semiclassical interpretation of our results indicates that electron motion in the rings is governed by regular rather than chaotic motion, an unexplored regime in many-electron quantum dots. This opens a way to experiments where even more complex structures can be investigated at a quantum mechanical level.

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PubMed2001

Conversion of spin into directed electric current in quantum wells.

A nonequilibrium population of spin-up and spin-down states in quantum well structures has been achieved applying circularly polarized radiation. The spin polarization results in a directed motion of free carriers in the plane of a quantum well perpendicular to the direction of light propagation. Because of the spin selection rules the direction of the current is determined by the helicity of the light and can be reversed by switching the helicity from right to left handed. A microscopic model is presented which describes the origin of the photon helicity driven current. The model suggests that the system behaves as a battery which generates a spin polarized current.

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PubMed2001

Ising ferromagnetism and domain morphology in the fractional quantum Hall regime.

The density driven quantum phase transition between the unpolarized and fully spin polarized nu = 2/3 fractional quantum Hall state is accompanied by hysteresis in accord with 2D Ising ferromagnetism and domain formation. The temporal behavior is reminiscent of the Barkhausen and time-logarithmic magnetic after-effects ubiquitous in familiar ferromagnets. It too suggests domain morphology and, in conjunction with NMR, intricate domain dynamics, which is partly mediated by the contact hyperfine interaction with nuclear spins of the host semiconductor.

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PubMed2001

Signatures of spin pairing in chaotic quantum dots.

Coulomb blockade resonances are measured in a GaAs quantum dot in which both shape deformations and interactions are small. The parametric evolution of the Coulomb blockade peaks shows a pronounced pair correlation in both position and amplitude, which is interpreted as spin pairing. As a consequence, the nearest-neighbor distribution of peak spacings can be well approximated by a modified bimodal Wigner surmise, in which interactions are taken into account beyond the constant interaction model.

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PubMed2001

Quantum interference in artificial band structures.

Magnetotransport experiments on two-dimensional electron systems with an atomically precise, one-dimensional potential modulation reveal striking quantum interference oscillations. Within a semiclassical framework, they are recognized either as self-interference along closed orbits, many of them rendered possible by magnetic breakdown between Fermi contour segments of the artificial band structure, or as interference-enhanced backscattering. The known commensurability oscillations appear as a special case of the latter mechanism.

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PubMed2001

Recognizing heterogeneous distribution of platinum group elements (PGE) in geological materials by means of the Re-Os isotope system.

The identification of uncertainties caused by sample inhomogeneity, as distinct from those caused by sample preparation and measurement, is a challenging task. Use of chemometric methods to separate and estimate these contributions to the combined standard uncertainty of a measurement (uc) of an analytical result requires complex experiments. The difficulty of platinum group element measurement makes this task even more complex. But unless it can be demonstrated that sample inhomogeneity is the major contributor to the high variability of an analytical result one should be careful not to mistakenly attribute this to a nugget effect. In this contribution we are able to demonstrate in two special cases that irreproducible results (up to 90% RSD) for analysis of Os and Re in the pg g(-1) to ng g(-1) range are truly caused by a nugget effect and not by inadequacies of the analytical method.

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PubMed2001

Quantifying the measurement uncertainty of results from environmental analytical methods.

The Eurachem-CITAC Guide Quantifying Uncertainty in Analytical Measurement was put into practice in a public laboratory devoted to environmental analytical measurements. In doing so due regard was given to the provisions of ISO 17025 and an attempt was made to base the entire estimation of measurement uncertainty on available data from the literature or from previously performed validation studies. Most environmental analytical procedures laid down in national or international standards are the result of cooperative efforts and put into effect as part of a compromise between all parties involved, public and private, that also encompasses environmental standards and statutory limits. Central to many procedures is the focus on the measurement of environmental effects rather than on individual chemical species. In this situation it is particularly important to understand the measurement process well enough to produce a realistic uncertainty statement. Environmental analytical methods will be examined as far as necessary, but reference will also be made to analytical methods in general and to physical measurement methods where appropriate. This paper describes ways and means of quantifying uncertainty for frequently practised methods of environmental analysis. It will be shown that operationally defined measurands are no obstacle to the estimation process as described in the Eurachem/CITAC Guide if it is accepted that the dominating component of uncertainty comes from the actual practice of the method as a reproducibility standard deviation.

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PubMed2001

Simplified method for the determination of Ru, Pd, Re, Os, Ir and Pt in chromitites and other geological materials by isotope dilution ICP-MS and acid digestion.

A method for the determination of low Ru, Pd, Re, Os, Ir and Pt abundances in geological reference materials by isotope dilution inductively coupled plasma mass spectrometry (ICP-MS) after acid digestion in a high pressure asher (HPA-S) is presented. The digestion technique is similar to that using Carius tubes but easier to handle and reaches higher temperatures. Osmium can be determined as OsO4 with ICP-MS directly after digestion through a sparging technique. The remaining elements are preconcentrated by means of anion column chromatography. The resin is digested directly without elution leading to high yields but this causes problems if Zr is present at higher levels in the silicate rich materials. The analytical results for international platinum group element (PGE) reference materials, chromitite CHR-Bkg, basalt TDB-1 and gabbro WGB-1, are presented and compared with literature data, demonstrating the validity of the described method. Although higher in concentration, PGEs determined for reference material WGB-1 were worse than for TDB-1 indicating a more inhomogeneous distribution of the platinum group mineral phases. The low PGE abundance chromitite standard, CHR-Bkg, is likely to be homogeneous for Ru, Re, Os and Ir and is recommended as a reference material for the study of chromitites. Detection limits (3s x total procedure blank) range from 0.012 ng (Re and Os) to 0.77 ng (Pt), which could be further improved by applying higher quality acids.

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PubMed2000

Quantum hall ferromagnetism in a two-dimensional electron system

Experiments on a nearly spin degenerate two-dimensional electron system reveals unusual hysteretic and relaxational transport in the fractional quantum Hall effect regime. The transition between the spin-polarized (with fill fraction nu = 1/3) and spin-unpolarized (nu = 2/5) states is accompanied by a complicated series of hysteresis loops reminiscent of a classical ferromagnet. In correlation with the hysteresis, magnetoresistance can either grow or decay logarithmically in time with remarkable persistence and does not saturate. In contrast to the established models of relaxation, the relaxation rate exhibits an anomalous divergence as temperature is reduced. These results indicate the presence of novel two-dimensional ferromagnetism with a complicated magnetic domain dynamic.

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