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Biomedical subjects

W W Stewart

Publications and source records attributed to W W Stewart.

At least 37 records · Page 2Linked to original sources
PubMed1985

Parvovirus infection in pigs with necrotic and vesicle-like lesions.

Porcine parvovirus was isolated from many visceral organs and also from the brain, serum and skin specimens of swine with vesicular-like conditions. Severe lesions were reported to have occurred in the mouth, on the tongue and snout, on the coronary band and in the interdigital spaces. Also, parvoviral antigens were demonstrated, by immunofluorescence, in the outer layers of hair follicles in skin adjacent to coronary band lesions.

Animals↗
PubMed1985

Body composition in the cirrhotic patient with ascites: assessment of total exchangeable sodium and potassium with simultaneous serum electrolyte determination.

The precise mechanism of initiation and maintenance of the disturbed fluid and electrolyte balance in cirrhotic patients remains unclear. Measurement of total exchangeable potassium in 11 cirrhotic patients with ascites revealed marked depletion compared to 9 healthy volunteers. Total exchangeable potassium was 50.8 +/- 5.1 m moles/L TBW in the patient group compared to 75.2 +/- 3.4 m moles/L TBW in the control group (P less than 0.01, Mann-Whitney U Test). Total body exchangeable sodium measured 80.1 +/- 3.7 m mole/L TBW in the cirrhotic group, which is not significantly elevated compared to the value in healthy volunteers of 74.1 +/- 1.9 m mole/L TBW. Serum sodium was low in four of the cirrhotic patients (129-133 mEq/L); exchangeable sodium was low in only one of these four (53.4 m mole/L TBW). Serum potassium was low in two of the cirrhotics (2.6-2.9 mEq/L); total body potassium was depressed in both of these patients (43.5-50.1 m mole/L TBW). An additional three patients had a low total body potassium (29.6-48.9 m mole/L TBW) with normal serum levels (4.0-4.2 mEq/L). There was no correlation between serum and total exchangeable electrolyte levels (Pearson's regression, r = 0.16 and 0.23). This work confirms that serum levels are not reliable indicators of true body sodium and potassium stores. The decreased total exchangeable potassium appears to be related to loss of body cell mass rather than intracellular potassium depletion.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1984

Influence of propranolol on weight and salt and water homoeostasis in chronic liver disease.

Sixteen patients with chronic liver disease were treated with propranolol or placebo in a double-blind study. Skinfold thickness, total body water and exchangeable sodium, and urinary sodium were measured every 6 months for a year; body weight was measured every 2 (later every 3) months for 15 months. Propranolol treatment was associated with a significant rise in body weight after 9 months and significant rises in skinfold thickness and body fat after 12 months. Propranolol-treated patients showed a fall in total body water at 6 months and a rise in urinary sodium concentration at 12 months. They did not show the rise in total body exchangeable sodium that occurred in placebo-treated patients. Propranolol seems to affect salt and water homoeostasis favourably in patients with chronic liver disease.

Adipose Tissue↗
PubMed1981

Lucifer dyes--highly fluorescent dyes for biological tracing.

Lucifer dyes are intensity fluorescent 4-aminonaphthalimides which are readily visible in living cells at concentrations and levels of illumination at which they are nontoxic. Because of their low molecular weight they frequently pass from one cell to another; this widespread phenomenon, termed dye-coupling, is thought to reveal functional relationships between cells. Lucifer dyes can also be used for ultrastructural tracing by comparison of electron micrographs with light micrographs of the same thin section. In addition, they show promise for backfilling neurones through cut nerves, for visualizing the results of retrograde axonal transport and for the covalent labeling of macromolecules.

Animals↗
PubMed1979

Bacteriuria with intestinal loop urinary diversion in children.

Bacteriuria and intestinal loop urinary diversion with open (refluxing) ureterointestinal anastomoses did not prevent normal renal and body growth in 44 children, who were followed for 55.2 months. A comparison of the long-term use of sulfamethoxazole and nitrofurantoin with no treatment showed no statistically significant changes in the stoma, loop residual, renal function, serum electrolytes and treatment or prevention of bacteriuria.

Adolescent↗
PubMed1977

Vesical endometriosis in a postmenopausal woman: a case report.

A case of endometriosis of the bladder extending into the bowel in a postmenopausal woman is reported. The origin of the tissue is mere conjecture. Five years before the onset of bleeding the patient had had an abdominal hysterectomy that may have seeded the adjacent vesical and small bowel tissue. It is hypothesized that the exogenous estrogen stimulated this tissue until it penetrated the bladder mucosa.

Aged↗