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Biomedical subjects

W Vincken

Publications and source records attributed to W Vincken.

At least 109 records · Page 6Linked to original sources

Effect of neck position during radionuclide superior cavography. Its value in the diagnosis of superior vena cava obstruction due to retrosternal goiter.

In five patients with substernal goiter, three of whom presented with superior vena cava (SVC) syndrome, and in five normal subjects, radionuclide superior cavography (RNSC) was performed with extension and flexion of the neck during tracer administration (simultaneous bilateral injection of Tc-99m pertechnetate). When the tracer was injected during neck extension, venous flow pattern was abnormal in four of five patients, and transit time (TT) prolonged in three of five patients. In this posture, mean TT +/- 1 standard deviation (SD) was 6.3 +/- 2.6 s (range 3.5 to 9 s) for the five patients and 3.5 +/- 0.7 s (range 2.5 to 4.5 s) for a group of five control subjects. When the tracer was injected during neck flexion, all five patients showed abnormal flow patterns and prolonged TT (mean +/- 1 SD 10.1 +/- 4.1 s; range 4.4 to 16 s), in contrast to the control group where a slight decrease in TT was found (mean +/- 1 SD 3 +/- 0.6 s; range 2 to 3.5 s). In the presence of a substernal goiter, or any mobile mass at the thoracic inlet, impairment of venous flow through the SVC system appears to be a common occurrence, readily detectable by RNSC. RNSC should be performed with neck flexion during tracer injection, since in this posture its ability to detect compromised venous flow through the SVC system is enhanced, even in patients without a clinically apparent SVC syndrome.

Adult↗

Isolated paratracheal mass of tuberculous origin in an adult patient.

A 40-year-old man presented with a solitary mediastinal (right paratracheal) mass which proved to be due to Mycobacterium tuberculosis. While the incidence of tuberculosis has diminished in our countries, such unusual manifestations of tuberculosis as the present case, are still encountered. Tuberculosis, the "perfect imitator", should be included in the differential diagnosis of a mediastinal mass. Excision for therapeutic, as well as histological and bacteriological diagnostic, purposes should be supplemented by appropriate antituberculous chemotherapy.

Adult↗

Demonstration of a bronchopleural communication by inhalation of Kr-81m gas.

Suspicion of a persisting communication between the bronchial tree and the pleural space in a patient with surgically drained pneumothorax was confirmed by the inhalation of Kr-81m gas. Compared to other diagnostic methods, this technique is harmless and repeatable, and hence very convenient for the assessment and follow-up of persisting pneumothorax due to air-leaks and of bronchopleural fistulas of any cause.

Bronchial Fistula↗

[Legionnaire's disease contracted in Brussels. One case (author's transl)].

A 71-year-old patient living in a street where major road works were taking place developed diffuse bronchopneumonia with changes in hepatic and renal biochemical tests. Since neutrophilia was moderate and all bacteriological investigations were negative, the patient was given erythromycin and was tested for antibodies directed against Legionella pneumophila. The titers of these antibodies rose from 32 to 2048 after one month. The patient was cured.

Aged↗

Clinical usefulness and safety of bronchoalveolar lavage (BAL) in elderly patients.

Little is known about the indications, safety and clinical usefulness of bronchoalveolar lavage (BAL) in elderly patients. In order to address these issues, we reviewed our last 200 consecutive BAL procedures, of which 23 (11.5%) were performed in patients older than 75 years (range 75-90, mean age 80.7 years, 13 men and 10 women). All procedures were well tolerated and no complications were observed. In 17 of the 23 patients (74%), BAL results were compatible with or diagnostic for infectious pneumonia (6 cases), idiopathic pulmonary fibrosis (5 cases), lung cancer (2 cases), hypereosinophilic syndrome (2 cases), chronic eosinophilic pneumonia (1 case) and lymphoma (1 case). In 6 of the 23 patients (26%), BAL yielded no specific diagnostic information. These data indicate that BAL is a safe procedure with a high diagnostic yield in an elderly population with pulmonary disease of unknown origin.

Journal Article↗

Localised obliterative bronchitis due to non-occupational mineral dust inhalation.

We present a 56-year-old woman with an infiltrate in the right middle lobe secondary to obstruction of the right middle lobe bronchus by extensive submucosal fibrosis. This unique stenotic lesion of a central bronchus was caused by a domestically acquired localised central obstructive bronchitis due to the inhalation of mixed dust fibers, in the absence of advanced silicosis. This complication is a rare presentation of the myriad of pulmonary diseases associated with mineral dust inhalation.

Air Pollution, Indoor↗

Bronchoscopic cryotherapy: preliminary experience.

Our preliminary experience with the bronchoscopic application of cryotherapy using rapid decompression of liquid nitrous oxide as cooling agent is reported. Seventeen applications through rigid bronchoscopy in twelve patients were performed. A single cryotherapy session was successful in the debulking of obstructive malignant lesions of the central airways in five patients (four non-small cell carcinoma, one renal cell cancer metastasis), and in the treatment of a capillary haemangioma (one patient). Two sessions were successful in the treatment of a metastatic melanoma (one patient) and benign granulation tissue (one patient). Cryotherapy was also successful in the treatment of early bronchial cancer (carcinoma in situ) in four patients, requiring repetitive sessions in two. There were no complications or side-effects. These preliminary findings confirm the safety and efficacy of bronchoscopic cryotherapy in a variety of airway lesions.

Adult↗

Toxic intrathoracic goiter and mediastinal lymphadenopathy: an unusual presentation of systemic primary AL amyloidosis.

Mediastinal lymphadenopathy and goiter have been associated with primary amyloidosis, although not in the same patient. One previous case report described the association of an amyloid goiter and hyperthyroidism (due to Graves' disease) with primary amyloidosis. Till now no case reports of patients presenting simultaneously with mediastinal lymphadenopathy, intrathoracic amyloid goiter and hyperthyroidism as the first manifestation of systemic primary (idiopathic) amyloidosis have been described. The present case report describes the clinical, biological radiological and histological features in such a male patient.

Aged↗

Diaphragmatic pacing in the treatment of chronic respiratory insufficiency of quadriplegic patients.

Following our experience with diaphragmatic pacing in 2 quadriplegic patients with bilateral diaphragmatic paralysis, we here present the indication for and the surgical technique of bilateral implantation of a diaphragmatic pacemaker. This mode of artificial ventilation appears to be superior to positive pressure ventilation for longterm ventilatory assistance of these patients.

Adult↗