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W Ursinus

Publications and source records attributed to W Ursinus.

At least 19 recordsLinked to original sources
PubMed1986

[Experimental animal studies on the problem of sealing a woven vascular prosthesis and a textile patch by direct-current activated autologous blood].

The results of our animal experiments showed that the sealing of a woven vascular prosthesis or a textile patch by in vitro electrically activated blood by means of direct current is an alternative for the sealing by fibrin adhesive. The materials sealed in this way are resistant to the endogenic fibrinolysis. This simple and non-expensive method is not useful for heparinised blood and in disturbances of coagulation.

Animals↗
PubMed1985

[Animal experimental and clinical studies on the behavior of an in vitro electrically produced thrombus mass].

In the electric field the solid blood components will move to the anode because of their negative surface charge. When influenced by a direct current of constant force and duration a thrombus differing in size will develop depending on the composition of the coagulation system. This regularity could be used for diagnostic purposes. By means of experiments with animals and clinical examinations the development of the "electro-clot" is observed in vitro before and after the administration of heparin. In addition, the behaviour of the thrombus developed in vitro in the electric field is checked in patients affected with obstructive lung diseases. Here a correlation existing between the mass of the thrombus and hematocrit could be proved.

Adult↗
PubMed1985

[Patent ductus arteriosus in premature infants with respiratory distress syndrome].

Since April 1983 10 premature infants suffering from patent ductus arteriosus combined with respiratory distress syndrome have been seen at our dept. for being treated surgically. One infant came to death due to bronchopulmonary dysplasia. The first 6 cases of this series were dealt with in detail. The possibility of conservative treatment (Indomethazin) or ligature of the duct are discussed.

Birth Weight↗
PubMed1985

[Experimental studies on the problem of improving the myocardial blood circulation in an intraoperatively resuscitated heart].

A pumping system for supporting an intraoperatively failured heart is presented. This system consists of a bell-shaped receptacle for the heart and a pump with a working volume of 49 ml and a working pressure of 220 Torr. The pumping power is transmitted to the heart by means of an external pneumatic pressure line. The efficacy of the pump in the high pressure system amounted to 20-30 per cent. An effective coronary perfusion in case of a cardiac failure is guaranteed by a venous underpressure pump of this pumping system. A favourable influence was also observed in case of the low pressure system.

Animals↗
PubMed1984

The sealing of vascular prostheses using autologous electrically activated blood.

Due to preclotting of the vascular prosthesis, autologous blood has shown good results provided that heparinization has not become necessary, or blood coagulation disorders are not present. In cases where replacement of the aorta is performed in the thoracic cavity with extracorporeal circulation or in the case of severe coagulopathies, preclotting with autologous blood does not show satisfactory results. In this presentation we report on a new method of sealing vascular prostheses with the help of autologous blood activated electrically "in vitro". The direct current changes the blood in vitro into a thrombogenic substance. Sealing is effected by placing the outer wall of the prosthesis in electrically activated blood.

Adult↗
PubMed1984

[Mitral commissurotomy or mitral valve replacement. Comparison of results of closed and open operative procedures in acquired mitral valve stenoses and combined mitral valve defects, predominantly stenosis].

1012 closed operations for mitral stenoses, mitral restenoses and combined mitral and aortic stenoses were performed from 1963 to 1981. Moreover 888 operations were performed at the mitral valve from 1973 to October 1983 as open heart procedures: 676 cases of mitral valve replacement (MVR) including 7 cases of coronary artery operations; 4 cases both of mitral, aortic and tricuspidal valve replacement or mitral and tricuspidal valve replacement; 9 cases of valve reinsertion; 20 cases of open commissurotomy and 4 cases of annular plastic according to Wooler. The functional results after open operation are quite better than those after closed procedures. The rate of reoperations after MVR is only 3% but after closed operations more than 25%. In this way we believe the open operation to be the better way of treating acquired mitral stenosis. In our opinion the closed method may be used in cases of late pregnancy and in those centres having an insufficient capacity for open heart surgery to be performed.

Aortic Valve↗
PubMed1983

[Surgical treatment of the scimitar syndrome].

Anomalous pulmonary venous drainage of the right lung into the inferior vena cava is an uncommon congenital defect. In 440 patients suffering from atrial septal defect (with or without anomalous pulmonary venous drainage) we could demonstrate the Scimitar-Syndrome in five cases. The described side-to-side-anastomosis between the anomalous vein and the left or right atrium is an alternative procedure to well-known operative methods.

Adolescent↗
PubMed1983

[Sound spectrographic studies in the diagnosis of dysfunctions of mechanical heart valve prostheses (Björk-Shiley prostheses)].

A newly developed real-time sound spectroanalyzer was found to be capable of diagnosing malfunction of prosthetic heart valves (Björk-Shiley prostheses). Sound spectroanalysis was carried out 430 times on 257 patients with a prosthetic heart valve. The valvular click of prosthetic heart valves shows a typical sound spectroanalysis pattern in real time, with a high-frequency peak which diminishes beyond 25 kHz. Thrombosis of the prosthetic heart valve causes loss of the valvular click and reduction in the intensity of the high-frequency components, as shown in 4 patients. Thus the sound spectroanalysis appears to be a noninvasive technique which may allow early diagnosis of a thrombosed prosthetic heart valve. We believe this method to be superior to phonocardiography and echocardiography.

Aortic Valve↗
PubMed1983

[Aneurysm of the membranous septum of the heart. A diagnostic and therapeutic challenge].

Aneurysms of the membranous portion of the interventricular septum are considered to be rare cardiac lesions. Left ventricular angiography appears to be the only method to establish the specific intravital diagnosis. Rupture, infection, thromboembolism, and obstruction of the right ventricular outflow tract have been documented for complications of this malformation. Early resection should be performed before complications occur. 4 patients underwent successful open heart correction of the aneurysm. In another patient a bundle branch block was present and a pacemaker was implanted.

Adolescent↗
PubMed1983

[Dynamics of the heart rate in active orthostasis of patients with hemodynamically effective mitral valve stenosis].

Heart rate dynamics in response to active orthostasis of 10 min duration were examined in 48 patients with mitral stenosis and compared with the mean and diastolic pulmonary artery pressure. Classification of the characteristics of the heart rate was done according Drischel and co-workers (1963) using amplitude and time values. In contrast to healthy subjects, in patients with mitral stenosis the best regulatory behavior was observed in type B with lower pulmonary artery pressure, the least favorable regulatory dynamics being predominant in type A with higher pulmonary artery pressure. From a functional diagnostic point of view, regulatory efficiency can be graded on the following descending scale: (1) the best regulatory behavior in type B; (2) a decrease in the amplitude values in type B; (3) transition of the dynamics to type A; and (4) prolongation of the time values in type A. The pathophysiological mechanisms are changes in the sensitivity of dilatation receptors in the intrathoracic low-pressure system and of the carotid baroreceptors.

Blood Pressure↗
PubMed1982

[Primary benign intramural intracavitary cardiac tumors--clinical, diagnostic and therapeutic aspects].

10 cases of benign primary tumours of the heart (5 myxomas of the left atrium, 2 myxomas of the right atrium, 1 right-ventricular endothelioma of the endocardium, 1 left-ventricular pseudorhabdomyoma, 1 tumour of the interventricular septum) are described. The diagnostically decisive method was in 5 cases the heart catheterization with angiocardiography, furthermore in one case each the roentgenogram of the thorax, the echocardiography, the histology of embolic material, the operation as well as the autopsy. The echocardiography was available for 4 patients; in one case it was diagnostically decisive, delivered important additional informations in 2 patients and failed in one patient. With increasing propagation of the echocardiography, which in the opinion of the authors at least in all cases should be used before a planned invasive cardiological diagnosis, is to be reckoned with an improvement of the diagnosis of tumours of the heart and with an increase of the chances of a causal, namely the timely cardiosurgical therapy.

Adult↗