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Biomedical subjects

W Torinuki

Publications and source records attributed to W Torinuki.

54 records · Page 3Linked to original sources
PubMed1982

Chemiluminescence of UV-irradiated linolenic acid and squalene.

An emission spectral analysis was carried out on ultraweak chemiluminescence emitted from UVB-irradiated linolenic acid and squalene. The main emission species produced by the transition of (1 delta g) (1 delta g) dimer and an additional weak band near 477.5 nm (0, 0) by the transition of (1 delta g (1 epsilon g+) to (3 epsilon g-) (3 epsilon g-) were found by spectroscopic analysis of chemiluminescence in both cases of irradiated linolenic acid and of squalene. A distinct peak around 410-420 nm was observed in irradiated squalene and the emitter seems to be due to the excited carbonyl compound.

Linolenic Acids↗
PubMed1982

Effect of beta-carotene on ultraweak chemiluminescence of UVB-irradiated squalene.

An emission spectral analysis was carried out on chemiluminescence emitted from UVB-irradiated squalene. The main emission species produced by the transition of (1 delta g) (1 delta g) and (1 delta g) (1 sigma g +) to (3 sigma g -) (3 sigma g -) were found by spectroscopic analysis of the chemiluminescence. When beta-carotene was added to the irradiated squalene, its spectral pattern changed drastically and many peaks disappeared.

Carotenoids↗
PubMed1981

Histopathological studies on sun-exposed hexachlorobenzene-induced porphyric rat skin.

Hexachlorobenzene (HCB) is a porphyrogenic agent. The inducement of skin changes was attempted through repeated exposure of the skin of HCB-induced porphyric rats to sunlight. The following skin changes were produced in the porphyric rats; erythema, erosion, crust, skin thickening and scarring. Histopathological examination revealed the presence of acanthosis, vacuolization of the malpighian cells, subepidermal vesicle, fibrosis, dilatation and increase of the blood vessels and perivascular cell infiltration composed of lymphocytes, histiocytes and mast cells. The PAS stainability of blood vessel walls was slightly intensified. The assumption is that photosensitive flares were elicited within the short 2-month period though destruction of endothelial cells was not prominent. There were no distinct skin changes, clinically or histopathologically, in any of the three control groups.

Animals↗
PubMed1980

Lysosome destruction and lipoperoxide formation due to active oxygen generated from haematoporphyrin and UV irradiation.

The lysosomal enzymes, acid-phosphatase and beta-glucuronidase, were released from rat liver lysosome when exposed to 400 nm irradiation in the presence of haematoporphyrin, and the release was prevented by adding vitamin E, diazabicyclo-octane, bovine serum albumin, superoxide dismutase or D-mannitol to the reaction mixture. Monochromatic irradiation with wavelengths from 380 to 410 nm caused no significant differences in the release of lysosomal enzymes, but 420 nm irradiation caused three-fifths of that of 400 nm irradiation. The malondialdehyde level in rat liver homogenate increased after 400 nm irradiation in the presence of haematoporphyrin. Reduction of nitroblue-tetrazolium was not observed when haematoporphyrin was excited by 400 nm; it was considered that superoxide anion radical (O2--) was not primarily generated. The following mechanism was assumed: that porphyrin which had been excited by 400 nm, converted ground-state molecular oxygen (3O2) to excited singlet oxygen (1O2), which formed lipid peroxides in lysosomal membrane resulting in destruction of the membrane; skin changes would occur from these released lysosomal enzymes.

Acid Phosphatase↗
PubMed1980

A high skin protoporphyrin level in erythropoietic protoporphyria.

A high skin protoporphyrin level (4.36 micrograms/g wet weight) was detected in a 14-year-old girl with erythropoietic protoporphyria who died of protoporphyrin hepatopathy cirrhosis. Excess protoporphyrin was detected in the skin by our assay technique which was assumed to cause severe skin photosensitivity.

Adolescent↗
PubMed1977

Clinical course of atrophie blanche.

Lesions of atrophie blanche which developed in 2 patients with systemic lupus erythematosus have been followed up for 3 years. The observation was made that atrophie blanche was not always preceded by ulcers but healed directly as scars. It was assumed that atrophie blanche might not be a terminal stage of necrotizing angitis but an intermediate one in the healing process.

Adult↗
PubMed1977

Thin layer chromatography and fluorescent scanning analysis of porphyrins.

A combined technique of two dimensional thin layer chromatography with fluorescent scanning was applied to the estimation of urinary porphyrins in 2 patients with porphyria cutanea tarda. Porphyrin patterns were also examined with the technique on urine, liver and skin samples obtained from a hexachlorobenzene-induced porphyric rat. Results obtained showed that uroporphyrin and hepta-carboxylic porphyrin were predominant in the urine, liver and skin.

Adult↗
PubMed1976

Atrophie blanche examined with thermography.

Atrophie blanche developed in a 25-year-old man with systemic lupus erythematosus is reported. A thermographic examination was applied to estimate skin temperature, and the temperature was low on areas where lesions were distributed.

Adult↗
PubMed1975

Cat scratch disease.

Cat scratch disease developed on a 40-year-old wife was reported. Umbilicated papules closely resembling those in herpetic skin infection development on the areas which had been scratched by a cat a week ago. Obtained findings in the present case led us to a speculation that this disease was caused by herpes virus. 72 cases of this disease have been reported in Japan, and they were reviewed in the present paper.

Adolescent↗