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Biomedical subjects

W Thal

Publications and source records attributed to W Thal.

At least 37 records · Page 2Linked to original sources

[Bronchologic studies in East Germany: current status and perspectives].

Within a period of 8 years (1979 to 1986) there were performed in 21 centres of the German Democratic Republic 15,049 bronchoscopic investigations (in 49.6 per cent combined with a subsequent bronchography) in 11,717 children, including 2,054 (17.5 per cent) up to one year of age. The detailed analysis shows important trends, which allow a reasonable prognosis of the perspectives of pediatric bronchology in the GDR.

Bronchography↗

[Pulmonary alveolar microlithiasis].

Case report from a 12-years old russian girl with pulmonary alveolar microlithiasis. The diagnosis was confirmed by histologic examination from biopsy specimen of the lung. The differential diagnosis and the histomorphology are discussed.

Biopsy↗

[Electron microscopy studies of cilia of the bronchial tree in children with chronic bronchopulmonary diseases].

The results of an ultrastructural analysis of cilia in 30 children at the age of 11 month to 16 years are presented. Children with marked symptoms of chronic bronchitis were consciously chosen for examination. One group of 15 children was suffering from chronic bronchitis with bronchiectases. No bronchiectasis was found in the second group of 15 children with chronic bronchitis. Specific changes were more evident in the first group, whereas nonspecific changes were of equal frequency in both groups. Only in 3 patients of group I generalized specific defects could be demonstrated. In these cases mucociliary clearance was nearly not present. Ultrastructural changes of cilia in children with chronic nonspecific lung diseases enclose a wide spectrum. Compared to it generalized structural defects are rare and only in 3 cases of our study demonstrable (negative selection of a bronchological centre).

Adolescent↗

[What is established in the immotile cilia syndrome?].

For the first time in 1975 ultrastructural defects of the sperm tail and the cilia of the respiratory tract were recognized as causing male sterility and chronic bronchitis. A spectrum of ultrastructural defects leading to a restricted mucociliary clearance and chronic bronchitis was found by further investigations. Whereas genetically determined primary structural defects appear generally, secondary ciliary changes caused by chronic infections are found sporadically and not bound to a fixed pattern. Congenital and acquired specific ciliary alterations in the tubulin-dynein-system should be distinguished from nonspecific acquired alterations. A summary of the presently known ultrastructural changes is illustrated by findings of the authors.

Bronchi↗

[Value of computer tomography in bronchopulmonary diseases in childhood].

In 20 children with bronchopulmonary symptoms and striking x-ray-thorax-findings computer-tomography examinations were carried out in addition to the usual diagnosis. Mediastinal demand for room and screening for tumor are recognized as essential indications in infancy for the application of CT-diagnosis in the chest. Computerized tomography is also indicated if an anomaly of blood vessels is suspected. In all other pulmonal diseases CT gives valuable information but in no case it replaces a bronchologic examination.

Adolescent↗

[Decrease of tuberculosis in children in GDR - facts, data and conclusions].

With decrease of tuberculosis among children GDR to nearly insignificant numbers nonspecific respiratory diseases have taken precedence in the health care of children. Nevertheless tuberculosis must not be forgotten in differential diagnostic consideration. Prophylaxis of tuberculosis exposition is becoming a predominant task. Immunoprophylaxis by BCG-vaccination should be carried on, yet treatment of tuberculous children should be started centrally at the children's hospital for pulmonary diseases at Harzgerode (GDR) also further on. The following ambulatory therapy should be done under the control of the district centres for respiratory diseases among children in close cooperation with the appropriate policlinical department for pulmonary disease (PALT) and the hospital at Harzgerode. Tuberculosis has to remain an important component of medical education of students and postgraduate education of pediatricians in spite of its low incidence, in future too.

Adolescent↗