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Biomedical subjects

W T Poh

Publications and source records attributed to W T Poh.

30 records · Page 2Linked to original sources

Clinics in diagnostic imaging (17). Chronic eosinophilic pneumonia (CEP).

A 24-year-old Chinese woman presented with cough, chest pain, weight loss, low grade fever and bronchial breath sounds on auscultation. The diagnosis of chronic eosinophilic pneumonia was made on characteristic systemic and pulmonary clinical manifestations, blood eosinophilia and the striking chest radiographic appearance. This rare, idiopathic but benign condition responds well to corticosteroid treatment and the long term prognosis is excellent. The typical chest radiographic pattern of 'photographic negative of pulmonary oedema' in this condition is emphasised.

Adrenal Cortex Hormones↗

Use of prostate specific antigen (PSA) and transrectal ultrasound (TRUS) in the diagnosis of prostate cancer--a local experience.

Prostate specific antigen (PSA) and transrectal ultrasound (TRUS) are two new modalities added to improve our ability to diagnose prostate cancer at an early stage. We reviewed our own experience of 100 cancers among 579 men from August 1991 to October1994. The detection rate was 17.3%. Digital rectal examination (DRE) alone had a positive predictive value (PPV) of 39.9%. The PPV for PSA was 23%. The combination of PSA and DRE gave a PPV of 47.2%. TRUS had a PPV of 30.6%. Features of cancer on TRUS may be both hypoechoic or hyperechoic nodules which appeared to have almost equal proportions associated with cancer. The addition of age-specific ranges did not affect the PPV of PSA. The PPV of the combination of TRUS and DRE was 53%. With all 3 modalities combined, the PPV was 58.8%. An interesting finding from the study was the higher average PSA for benign and malignant disease in the local population and cases of acute retention of urine. There was a higher incidence of prostatitis and lower incidence of cancer in cases with retention of urine.

Adult↗

Fibro-inflammatory pseudotumour in the maxillary sinus.

We describe a rare case of fibro-inflammatory pseudotumour in the right maxillary sinus of a 13-year-old Chinese girl who presented with proptosis and radiological appearance suspicious of malignancy but was histologically benign. She underwent Caldwel-Luc operation and received prolonged steroid therapy. She is now free of the disease both clinically and radiologically 33 months after cessation of therapy.

Adolescent↗

Malignant granular cell tumour of the lower limb--a case report and review of the literature.

Granular cell tumour is a rare tumour of undetermined origin. Fewer than 1000 cases have been reported and less than 40 cases of malignant forms of this tumour have been described in the literature. We report a single case of the malignant form of granular cell tumour in the lower limb and review the literature regarding the possible origin of this tumour. Presently, wide surgical excision is the only modality of treatment for this lesion.

Granular Cell Tumor↗

Pulmonary alveolar proteinosis--a case report.

Pulmonary alveolar proteinosis is a relatively rare disease. Its etiology is unknown but it has been found associated with various opportunistic infections as well as immunological conditions. The clinical and radiological features may be indistinguishable from other respiratory disorders and diagnosis is often dependent on histology. Its course can vary from progressive deterioration to spontaneous improvement and treatment with bronchopulmonary lavage may not always be necessary. Many theories regarding pathogenesis have been put forward and most of these centre upon the roles of alveolar macrophages. We describe a case of Pulmonary Alveolar Proteinosis in a local Oriental male and reviewed the current understanding of its pathogenesis.

Humans↗

Thyroid papillary carcinoma with unusual breast metastasis.

Breast metastasis from thyroid carcinoma is a rare occurrence. We report a case of immunohistologically proven breast metastasis from a thyroid papillary carcinoma. The association of primary breast carcinoma and thyroid carcinoma is noted and the usefulness of immunohistological techniques emphasised especially when histological assessment is difficult.

Aged↗