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Biomedical subjects

W T Chu

Publications and source records attributed to W T Chu.

8 recordsLinked to original sources
PubMed2004

Optimization of an accelerator-based epithermal neutron source for neutron capture therapy.

A modeling investigation was performed to choose moderator material and size for creating optimal epithermal neutron beams for BNCT based on a proton accelerator and the (7)Li(p,n)(7)Be reaction as a neutrons source. An optimal configuration is suggested for the beam shaping assembly made from polytetrafluoroethylene and magnesium fluorine to be placed on high current IPPE proton accelerator KG-2.5. Results of calculation were experimentally tested and are in good agreement with measurements.

Boron Neutron Capture Therapy↗
PubMed1999

Measurements of low-energy (d,n) reactions for BNCT. Boron Neutron Capture Therapy.

Neutron yields and energy spectra have been measured for various deuteron-induced reactions at low energy. Neutrons of energy > 100 keV emitted in the 9Be(d,n)10B, 12C(d,n)13N, and 13C(d,n)14N reactions at Ed= 1.5 MeV were detected at five angles by means of liquid scintillator detectors. While low-energy neutrons were observed in all studied reactions, only 13C(d,n)14N is characterized by a relatively large yield with spectral features potentially interesting for an accelerator-based neutron source for BNCT.

Beryllium↗
PubMed1976

Antiinflammatory reaction associated with murine L1210 leukemia.

Mice bearing L1210 leukemia did not show impaired humoral or cellular immune response to antigenic stimulation druing the early stage of the tumor, and a depressed response was noted only in the terminal stage. L1210 cells were shown to suppress inflammatory reaction in vivo.

Animals↗
PubMedDate not supplied

Direct data link between a CT scanner and a radiation treatment planning system.

A direct data link between a CT scanner and a radiation treatment planning system has been developed. The link transmits the data serially over a coaxial cable using the pseudo-paper-tape punch and reader (serial PIO) interfaces. The data transmission rate with error-check is approximately 25,000 8-bit bytes/s. This translates to about 7 s for transferring a CT scan with a 320-pixel diameter.

Computers↗
PubMedDate not supplied

Wobbler facility for biomedical experiments.

A system for spreading relativistic heavy ion beams into large uniform radiation fields has been developed. The charged particles passing through the system are deflected into azimuthally symmetric distributions which can then be superimposed to produce dose distributions as large as 30 cm in diameter with less than +/- 3.5% variation in uniformity.

Ions↗
PubMedDate not supplied

Accelerated helium-ion beams for radiotherapy and stereotactic radiosurgery.

A new beam line for radiotherapy and radiosurgery with accelerated helium-ion beams has been set up at the Bevalac. The new treatment room has been equipped with a very precise patient positioner in order to utilize the superior dose localization properties of light-ion beams. The beam spreading and shaping system is described, the trade-offs involved in positioning the beam modifying devices are discussed, and the physical properties of the generated radiation fields are reported. The Bragg peak modulation by axial beam stacking employing a variable range shifter is explained and the control system including beam monitoring and dosimetry is presented.

Helium↗